Editorial Board Members’ Collection Series: New Strategies to Overcome Antibiotic Resistance

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".

Deadline for manuscript submissions: 20 September 2024 | Viewed by 132

Special Issue Editors

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Guest Editor
Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20133 Milan, Italy
Interests: Study of the effects of drugs on the internalization process of Helicobacter pylori; molecular studies of resistance to antimicrobial agents; effect of new molecules against H. pylori in sessile and planktonic form; pathogenicity of H. pylori; antimicrobial susceptibility testing of H. pylori to new synthetized drugs.
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Guest Editor
Department of Pharmacy, University “G. d'Annunzio” of Chieti-Pescara, Chieti, Italy
Interests: chemical modification of natural compounds; medicinal chemistry; food chemistry; antioxidants; antimicrobials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Antibiotic resistance is becoming a global public health issue due to the increasing morbidity, mortality, and healthcare costs attributed to resistant bacteria, as also reported in a recent publication by the World Health Organization. Non-rational antibiotic use, including overuse, abuse, misuse in terms of dose and duration, and use with the wrong indication, exacerbates the phenomenon. Furthermore, antibiotic resistance does not only concern human health, but it must be seen from a 'one health' perspective. Therefore, many approaches have to be considered. Despite the increasing failure of current antimicrobial therapy, no new antibiotics have been approved. Given that, multi drug-resistant bacteria have also been isolated. The aim of this Special Issue is to collect and analyze in-depth the approaches applied or proposed as alternatives (direct antibacterials or resistance modifiers) to traditional drugs. These strategies include combination therapy with natural and synthetic compounds, agents targeting enzymes or proteins responsible for antibacterial resistance (biofilm, Quorum Sensing, efflux pumps, virulence factors, and the content of bacterial extracellular vesicles), new bacterial targets, resistant bacteria, nanosystems, drug delivery systems, and physico-chemical methods (e.g., photodynamic therapy). Collectively, these strategies may holistically contribute to the treatment of multi-drug-resistant bacteria in clinical settings. Clinical and epidemiological studies, unravelling pharmacological potentials, are also welcome, as well as studies on the role of human gut microbiota modulation to limit or counteract the spread of these infections.

Dr. Francesca Sisto
Dr. Simone Carradori
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • antimicrobial resistance
  • biofilm
  • new targets
  • synthetic drugs
  • natural compounds
  • quorum sensing
  • in vivo models
  • checkerboard assay
  • resistance modifiers
  • probiotics

Published Papers

This special issue is now open for submission.
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