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Biosensors, Volume 13, Issue 11

November 2023 - 43 articles

Cover Story: Prostate cancer is responsible for around 7.3% of cancer deaths in men. However, when detected early, the survival rate increases in almost 100% of patients. Techniques such as rectal examination and measuring the PSA level in the blood are used to detect cancer, but they have low specificity and sensitivity. Studies have revealed that Stanniocalcin-1 (STC-1) can be used as a biomarker for prostate cancer. In this work, four different STC-1 antibody sensors from a fish were deposited on interdigitated gold electrodes using layer-on-layer thin film preparation and self-assembly techniques. The detection of different STC-1 antigen concentrations was performed using impedance spectroscopy. The electrical characterization of the films was carried out using principal component analysis to validate them as effective sensors. View this paper
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Articles (43)

  • Feature Paper
  • Article
  • Open Access
2 Citations
2,567 Views
17 Pages

Biosensors Based on Stanniocalcin-1 Protein Antibodies Thin Films for Prostate Cancer Diagnosis

  • Renato Ferreira,
  • Paulo A. Ribeiro,
  • Adelino V. M. Canário and
  • Maria Raposo

10 November 2023

Prostate cancer is one of the most prevalent tumors in men, accounting for about 7.3% of cancer deaths. Although there are several strategies for diagnosing prostate cancer, these are only accurate when the tumor is already at a very advanced stage,...

  • Review
  • Open Access
13 Citations
11,645 Views
48 Pages

Chemical Trends in Sample Preparation for Nucleic Acid Amplification Testing (NAAT): A Review

  • Soo Min Lee,
  • Hari Kalathil Balakrishnan,
  • Egan H. Doeven,
  • Dan Yuan and
  • Rosanne M. Guijt

10 November 2023

Nucleic acid amplification testing facilitates the detection of disease through specific genomic sequences and is attractive for point-of-need testing (PONT); in particular, the early detection of microorganisms can alert early response systems to pr...

  • Article
  • Open Access
4 Citations
2,927 Views
15 Pages

9 November 2023

Raman enhancement techniques are essential for gas analysis to increase the detection sensitivity of a Raman spectroscopy system. We have developed an efficient Raman enhancement technique called the collision-enhanced Raman scattering (CERS), where...

  • Article
  • Open Access
5 Citations
2,607 Views
13 Pages

A Hand-Held Platform for Boar Sperm Viability Diagnosis Based on Smartphone

  • Yunhong Zheng,
  • Hang Yin,
  • Chengxian Zhou,
  • Wei Zhou,
  • Zhijie Huan and
  • Weicheng Ma

8 November 2023

The swine fever virus seriously affects pork production, and to improve pork production, pig breeding efficiency needs to be improved, and the detection of boar sperm activity is an important part of the pig breeding process. Traditional laboratory t...

  • Review
  • Open Access
17 Citations
6,377 Views
34 Pages

Plasmonic Nanoparticle-Enhanced Optical Techniques for Cancer Biomarker Sensing

  • Li Fu,
  • Cheng-Te Lin,
  • Hassan Karimi-Maleh,
  • Fei Chen and
  • Shichao Zhao

8 November 2023

This review summarizes recent advances in leveraging localized surface plasmon resonance (LSPR) nanotechnology for sensitive cancer biomarker detection. LSPR arising from noble metal nanoparticles under light excitation enables the enhancement of var...

  • Review
  • Open Access
64 Citations
13,253 Views
48 Pages

7 November 2023

The promising field of organic electronics has ushered in a new era of biosensing technology, thus offering a promising frontier for applications in both medical diagnostics and environmental monitoring. This review paper provides a comprehensive ove...

  • Article
  • Open Access
4 Citations
3,203 Views
12 Pages

7 November 2023

Clustered regularly interspaced short palindromic repeats (CRISPR)- CRISPR-associated protein 9 (Cas9) genome editing technology is widely used for gene editing because it provides versatility in genetic manipulation. Several methods for regulating C...

  • Article
  • Open Access
8 Citations
2,807 Views
15 Pages

A Novel Combination Therapy Tβ4/VIP Protects against Hyperglycemia-Induced Changes in Human Corneal Epithelial Cells

  • Abdul Shukkur Ebrahim,
  • Thomas W. Carion,
  • Thanzeela Ebrahim,
  • Jeff Win,
  • Hussein Kani,
  • Yuxin Wang,
  • Ashten Stambersky,
  • Ahmed S. Ibrahim,
  • Gabriel Sosne and
  • Elizabeth A. Berger

7 November 2023

Despite the prevalence of diabetic retinopathy, the majority of adult diabetic patients develop visually debilitating corneal complications, including impaired wound healing. Unfortunately, there is limited treatment for diabetes-induced corneal dama...

  • Article
  • Open Access
8 Citations
4,021 Views
15 Pages

Optical Diffraction Tomography and Raman Confocal Microscopy for the Investigation of Vacuoles Associated with Cancer Senescent Engulfing Cells

  • Silvia Ghislanzoni,
  • Jeon Woong Kang,
  • Arianna Bresci,
  • Andrea Masella,
  • Koseki J. Kobayashi-Kirschvink,
  • Dario Polli,
  • Italia Bongarzone and
  • Peter T. C. So

7 November 2023

Wild-type p53 cancer therapy-induced senescent cells frequently engulf and degrade neighboring ones inside a massive vacuole in their cytoplasm. After clearance of the internalized cell, the vacuole persists, seemingly empty, for several hours. Despi...

  • Article
  • Open Access
9 Citations
3,518 Views
12 Pages

7 November 2023

An accurate and simple screening method has been developed for the determination of fluoroquinolone antibiotics. Carbon dots were synthesized by simple hydrothermal treatment as highly fluorescent nano-sensors. They were subsequently used in the synt...

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Biosensors - ISSN 2079-6374