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Biosensors, Volume 12, Issue 5

May 2022 - 102 articles

Cover Story: Our research incorporates the DNA–gold affinity interaction into an electrochemical nucleic-acid-based direct adsorption platform for the voltammetric detection of HOTAIR long noncoding RNA. Our platform utilizes highly specific and sensitive nanomaterials coupled with screen-printed gold electrodes. The assay features three main steps: (i) magnetic bead capture of HOTAIR targets, (ii) magnetic purification and isolation of targets, and (iii) direct adsorption and detection via interfacial affinity interaction. We demonstrate detection as low as 1 pM for samples containing designated proportions of synthetic HOTAIR spiked in buffer as well as healthy plasma samples. Our method shows huge potential in diagnostics due to its disposable, simple, inexpensive, easy-to-store, and portable design. View this paper
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Articles (102)

  • Article
  • Open Access
23 Citations
5,836 Views
23 Pages

Portable Respiration Monitoring System with an Embroidered Capacitive Facemask Sensor

  • Mitar Simić,
  • Adrian K. Stavrakis,
  • Ankita Sinha,
  • Velibor Premčevski,
  • Branko Markoski and
  • Goran M. Stojanović

15 May 2022

Respiration monitoring is a very important indicator of health status. It can be used as a marker in the recognition of a variety of diseases, such as sleep apnea, asthma or cardiac arrest. The purpose of the present study is to overcome limitations...

  • Communication
  • Open Access
6 Citations
3,044 Views
9 Pages

14 May 2022

As a common herbicide in farmland, there has been wide concern over quinclorac residue because of its potential risks to the environment and human health. For the detection and monitoring of quinclorac residue in the environment, enzyme-linked immuno...

  • Article
  • Open Access
20 Citations
4,245 Views
16 Pages

Multilayered Mesoporous Composite Nanostructures for Highly Sensitive Label-Free Quantification of Cardiac Troponin-I

  • Mohsen Saeidi,
  • Mohammad Ali Amidian,
  • Sana Sheybanikashani,
  • Hossein Mahdavi,
  • Homayoon Alimohammadi,
  • Leila Syedmoradi,
  • Fatemeh Mohandes,
  • Ali Zarrabi,
  • Elnaz Tamjid and
  • Kobra Omidfar
  • + 1 author

14 May 2022

Cardiac troponin-I (cTnI) is a well-known biomarker for the diagnosis and control of acute myocardial infarction in clinical practice. To improve the accuracy and reliability of cTnI electrochemical immunosensors, we propose a multilayer nanostructur...

  • Article
  • Open Access
13 Citations
4,475 Views
12 Pages

13 May 2022

Enzymatic biosensors based on glucose oxidase has been proven to be one of the effective strategies for the detection of glucose and contributed to health improvements. Therefore, research and debates to date are ongoing in an attempt to find the mos...

  • Review
  • Open Access
11 Citations
5,258 Views
20 Pages

13 May 2022

Photoacoustic imaging (PAI) is an invaluable tool in biomedical imaging, as it provides anatomical and functional information in real time. Its ability to image at clinically relevant depths with high spatial resolution using endogenous tissues as co...

  • Article
  • Open Access
8 Citations
3,160 Views
14 Pages

Field-Effect Capacitors Decorated with Ligand-Stabilized Gold Nanoparticles: Modeling and Experiments

  • Arshak Poghossian,
  • Tobias Karschuck,
  • Patrick Wagner and
  • Michael J. Schöning

13 May 2022

Nanoparticles are recognized as highly attractive tunable materials for designing field-effect biosensors with enhanced performance. In this work, we present a theoretical model for electrolyte-insulator-semiconductor capacitors (EISCAP) decorated wi...

  • Article
  • Open Access
23 Citations
6,442 Views
13 Pages

A Patient-Ready Wearable Transcutaneous CO2 Sensor

  • Juan Pedro Cascales,
  • Xiaolei Li,
  • Emmanuel Roussakis and
  • Conor L. Evans

13 May 2022

Continuously monitoring transcutaneous CO2 partial pressure is of crucial importance in the diagnosis and treatment of respiratory and cardiac diseases. Despite significant progress in the development of CO2 sensors, their implementation as portable...

  • Communication
  • Open Access
17 Citations
4,410 Views
10 Pages

13 May 2022

The rates of diabetes throughout the world are rising rapidly, impacting nearly every country. New research is focused on better ways to monitor and treat this disease. Breath acetone levels have been defined as a biomarker for diabetes. The developm...

  • Article
  • Open Access
9 Citations
4,123 Views
16 Pages

Electrochemical Biosensor Using Nitrogen-Doped Graphene/Au Nanoparticles/DNAzyme for Ca2+ Determination

  • Zhixue Yu,
  • Hui Wang,
  • Yiguang Zhao,
  • Fan Zhang,
  • Xiangfang Tang and
  • Benhai Xiong

12 May 2022

An electrochemical biosensor for detecting Ca2+ concentration was proposed using glass carbon electrodes (GCEs) modified with nitrogen-doped graphene (NGR), gold nanoparticles (AuNPs) and DNAzyme. The resistance signal was amplified through two metho...

  • Article
  • Open Access
28 Citations
5,869 Views
14 Pages

12 May 2022

The dynamic immune response to various diseases and therapies has been considered a promising indicator of disease status and therapeutic effectiveness. For instance, the human peripheral blood mononuclear cell (PBMC), as a major player in the immune...

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Biosensors - ISSN 2079-6374