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Biosensors, Volume 12, Issue 5

May 2022 - 102 articles

Cover Story: Our research incorporates the DNA–gold affinity interaction into an electrochemical nucleic-acid-based direct adsorption platform for the voltammetric detection of HOTAIR long noncoding RNA. Our platform utilizes highly specific and sensitive nanomaterials coupled with screen-printed gold electrodes. The assay features three main steps: (i) magnetic bead capture of HOTAIR targets, (ii) magnetic purification and isolation of targets, and (iii) direct adsorption and detection via interfacial affinity interaction. We demonstrate detection as low as 1 pM for samples containing designated proportions of synthetic HOTAIR spiked in buffer as well as healthy plasma samples. Our method shows huge potential in diagnostics due to its disposable, simple, inexpensive, easy-to-store, and portable design. View this paper
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Articles (102)

  • Article
  • Open Access
5 Citations
3,569 Views
15 Pages

Analysis of Mn2+ and Zn2+ Ions in Macroalgae with Heteroelement-Doped Carbon-Based Fluorescent Probe

  • Hui Xu,
  • Xin You,
  • Yue Lu,
  • Peng Liang,
  • Zhihui Luo,
  • Yiwei Wang,
  • Shaoxiao Zeng and
  • Hongliang Zeng

22 May 2022

Kelp and laver are large economic macroalgae in China, which are rich in nutrients, especially Mn and Zn. Excessive intake of Mn and Zn can be harmful to the human body. Therefore, it is necessary to develop a convenient and efficient method to detec...

  • Article
  • Open Access
4 Citations
3,355 Views
11 Pages

Energy-Efficient, On-Demand Activation of Biosensor Arrays for Long-Term Continuous Health Monitoring

  • Jonathan Lundquist,
  • Benjamin Horstmann,
  • Dmitry Pestov,
  • Umit Ozgur,
  • Vitaliy Avrutin and
  • Erdem Topsakal

21 May 2022

Wearable biosensors for continuous health monitoring, particularly those used for glucose detection, have a limited operational lifetime due to biodegradation and fouling. As a result, patients must change sensors frequently, increasing cost and pati...

  • Review
  • Open Access
52 Citations
9,390 Views
26 Pages

Electronic Sensor Technologies in Monitoring Quality of Tea: A Review

  • Seyed Mohammad Taghi Gharibzahedi,
  • Francisco J. Barba,
  • Jianjun Zhou,
  • Min Wang and
  • Zeynep Altintas

20 May 2022

Tea, after water, is the most frequently consumed beverage in the world. The fermentation of tea leaves has a pivotal role in its quality and is usually monitored using the laboratory analytical instruments and olfactory perception of tea tasters. De...

  • Review
  • Open Access
32 Citations
6,936 Views
26 Pages

20 May 2022

Better diagnostics are always essential for the treatment and prevention of a disease. Existing technologies for detecting infectious and non-infectious diseases are mostly tedious, expensive, and do not meet the World Health Organization’s (WH...

  • Article
  • Open Access
13 Citations
3,945 Views
16 Pages

An Artifact-Resistant Feature SKNAER for Quantifying the Burst of Skin Sympathetic Nerve Activity Signal

  • Yantao Xing,
  • Yike Zhang,
  • Zhijun Xiao,
  • Chenxi Yang,
  • Jiayi Li,
  • Chang Cui,
  • Jing Wang,
  • Hongwu Chen,
  • Jianqing Li and
  • Chengyu Liu

20 May 2022

Evaluation of sympathetic nerve activity (SNA) using skin sympathetic nerve activity (SKNA) signal has attracted interest in recent studies. However, signal noises may obstruct the accurate location for the burst of SKNA, leading to the quantificatio...

  • Article
  • Open Access
9 Citations
3,239 Views
8 Pages

Bioluminescent-Inhibition-Based Biosensor for Full-Profile Soil Contamination Assessment

  • Elizaveta M. Kolosova,
  • Oleg S. Sutormin,
  • Aleksandr A. Shpedt,
  • Ludmila V. Stepanova and
  • Valentina A. Kratasyuk

19 May 2022

A bioluminescent-enzyme-inhibition-based assay was applied to predict the potential toxicity of the full profile of the following soil samples: agricultural grassland, 10-year fallow land (treated with remediation processes for 10 years) and uncontam...

  • Article
  • Open Access
17 Citations
3,628 Views
10 Pages

19 May 2022

We synthesized core-shell-shaped nanocomposites composed of a single-walled carbon nanotube (SWCNT) and heptadecafluorooctanesulfonic acid-doped polypyrrole (C8F-doped-PPy)/phenyllatic acid (PLA), i.e., C8F-doped-PPy/PLA@SWCNT, for detecting acetone...

  • Article
  • Open Access
7 Citations
3,603 Views
16 Pages

Fiber-Optic Distributed Sensing Network for Thermal Mapping of Gold Nanoparticles-Mediated Radiofrequency Ablation

  • Akbota Sametova,
  • Sabit Kurmashev,
  • Zhannat Ashikbayeva,
  • Aida Amantayeva,
  • Wilfried Blanc,
  • Timur Sh. Atabaev and
  • Daniele Tosi

18 May 2022

In this work, we report the design of an optical fiber distributed sensing network for the 2-dimensional (2D) in situ thermal mapping of advanced methods for radiofrequency thermal ablation. The sensing system is based on six high-scattering MgO-dope...

  • Article
  • Open Access
19 Citations
3,958 Views
12 Pages

Investigation and Comparison of Specific Antibodies’ Affinity Interaction with SARS-CoV-2 Wild-Type, B.1.1.7, and B.1.351 Spike Protein by Total Internal Reflection Ellipsometry

  • Ieva Plikusiene,
  • Vincentas Maciulis,
  • Silvija Juciute,
  • Ruta Maciuleviciene,
  • Saulius Balevicius,
  • Arunas Ramanavicius and
  • Almira Ramanaviciene

18 May 2022

SARS-CoV-2 vaccines provide strong protection against COVID-19. However, the emergence of SARS-CoV-2 variants has raised concerns about the efficacy of vaccines. In this study, we investigated the interactions of specific polyclonal human antibodies...

  • Article
  • Open Access
2 Citations
3,501 Views
10 Pages

Easy-to-Operate Co-Flow Step Emulsification Device for High-Throughput Three-Dimensional Cell Culture

  • Chunyang Wei,
  • Chengzhuang Yu,
  • Shanshan Li,
  • Tiejun Li,
  • Jiyu Meng and
  • Junwei Li

18 May 2022

Cell culture plays an essential role in tissue engineering and high-throughput drug screening. Compared with two-dimensional (2D) in vitro culture, three-dimensional (3D) in vitro culture can mimic cells in vivo more accurately, including complex cel...

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Biosensors - ISSN 2079-6374