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Biosensors, Volume 12, Issue 3

2022 March - 49 articles

Cover Story: The status of lactate has evolved from being considered a waste product of cellular metabolism to a useful metabolic substrate, and more recently to a signaling molecule. The fluctuations of lactate levels within biological tissues, in particular in the interstitial space, are crucial to assess with high spatial and temporal resolution, best achieved using cellular imaging approaches. In this study, we evaluated the suitability of the lactate receptor, the hydroxycarboxylic acid receptor 1 (HCAR1, formerly named GPR81), as a basis for the development of a genetically encoded fluorescent lactate biosensor. View this paper
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Articles (49)

  • Article
  • Open Access
25 Citations
5,540 Views
13 Pages

Folic Acid-Modified Fluorescent-Magnetic Nanoparticles for Efficient Isolation and Identification of Circulating Tumor Cells in Ovarian Cancer

  • Yue Pan,
  • Zhili Wang,
  • Jialing Ma,
  • Tongping Zhou,
  • Zeen Wu,
  • Pi Ding,
  • Na Sun,
  • Lifen Liu,
  • Renjun Pei and
  • Weipei Zhu

21 March 2022

Ovarian cancer (OC) is a lethal disease occurring in women worldwide. Due to the lack of obvious clinical symptoms and sensitivity biomarkers, OC patients are often diagnosed in advanced stages and suffer a poor prognosis. Circulating tumor cells (CT...

  • Review
  • Open Access
121 Citations
17,044 Views
22 Pages

DNA-Based Biosensors for the Biochemical Analysis: A Review

  • Yu Hua,
  • Jiaming Ma,
  • Dachao Li and
  • Ridong Wang

20 March 2022

In recent years, DNA-based biosensors have shown great potential as the candidate of the next generation biomedical detection device due to their robust chemical properties and customizable biosensing functions. Compared with the conventional biosens...

  • Article
  • Open Access
24 Citations
7,841 Views
12 Pages

19 March 2022

Au nanoparticles (AuNPs) have been used as signal reporters in colorimetric lateral flow immunoassays (LFAs) for decades. However, it remains a major challenge to significantly improve the detection sensitivity of traditional LFAs due to the low brig...

  • Article
  • Open Access
20 Citations
5,260 Views
15 Pages

Microfluidic-Assisted Fabrication of Dual-Coated pH-Sensitive Mesoporous Silica Nanoparticles for Protein Delivery

  • Berrin Küçüktürkmen,
  • Wali Inam,
  • Fadak Howaili,
  • Mariam Gouda,
  • Neeraj Prabhakar,
  • Hongbo Zhang and
  • Jessica M. Rosenholm

18 March 2022

Microfluidics has become a popular method for constructing nanosystems in recent years, but it can also be used to coat other materials with polymeric layers. The polymeric coating may serve as a diffusion barrier against hydrophilic compounds, a res...

  • Review
  • Open Access
91 Citations
10,102 Views
17 Pages

17 March 2022

The advancement of science and technology has led to the recent development of highly sensitive pathogen biosensing techniques. The effective treatment of pathogen infections requires sensing technologies to not only be sensitive but also render resu...

  • Review
  • Open Access
16 Citations
5,558 Views
20 Pages

Microfluidics-Based Biosensing Platforms: Emerging Frontiers in Point-of-Care Testing SARS-CoV-2 and Seroprevalence

  • Elda A. Flores-Contreras,
  • Reyna Berenice González-González,
  • Iram P. Rodríguez-Sánchez,
  • Juan F. Yee-de León,
  • Hafiz M. N. Iqbal and
  • Everardo González-González

17 March 2022

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the ongoing COVID-19 (coronavirus disease-2019) outbreak and has unprecedentedly impacted the public health and economic sector. The pandemic has forced researchers to focus on the a...

  • Article
  • Open Access
13 Citations
5,056 Views
17 Pages

Application of a Novel Biosensor for Salivary Conductivity in Detecting Chronic Kidney Disease

  • Chen-Wei Lin,
  • Yuan-Hsiung Tsai,
  • Yen-Pei Lu,
  • Jen-Tsung Yang,
  • Mei-Yen Chen,
  • Tung-Jung Huang,
  • Rui-Cian Weng and
  • Chun-Wu Tung

17 March 2022

The prevalence of chronic kidney disease (CKD) is increasing, and it brings an enormous healthcare burden. The traditional measurement of kidney function needs invasive blood tests, which hinders the early detection and causes low awareness of CKD. W...

  • Perspective
  • Open Access
24 Citations
5,876 Views
15 Pages

Preparation and Applications of Electrospun Nanofibers for Wearable Biosensors

  • Tengzhou Xu,
  • Guojing Ji,
  • Hui Li,
  • Jiaduo Li,
  • Zhou Chen,
  • Desire Emefa Awuye and
  • Jie Huang

17 March 2022

The emergence of nanotechnology has provided many new ideas and innovations in the field of biosensors. Electrospun nanofibers have many excellent properties such as high specific surface area, high porosity, low cost, high efficiency, and they can b...

  • Article
  • Open Access
6 Citations
3,664 Views
14 Pages

Simultaneously Acquiring Optical and Acoustic Properties of Individual Microalgae Cells Suspended in Water

  • Hongjian Wang,
  • Ran Liao,
  • Zhihang Xiong,
  • Zhao Wang,
  • Jiajin Li,
  • Qian Zhou,
  • Yi Tao and
  • Hui Ma

15 March 2022

Microalgae play a vital role in aquatic ecological research, but the fine classification of these tiny and various microalgae cells is still challenging for the community. In this paper, we propose a multimodality technique to simultaneously acquire...

  • Article
  • Open Access
11 Citations
3,950 Views
17 Pages

Fluorescence Sensors Based on Hydroxycarbazole for the Determination of Neurodegeneration-Related Halide Anions

  • Víctor González-Ruiz,
  • Ángel Cores,
  • M. Mar Caja,
  • Vellaisamy Sridharan,
  • Mercedes Villacampa,
  • M. Antonia Martín,
  • Ana I. Olives and
  • J. Carlos Menéndez

14 March 2022

The environmental presence of anions of natural origin or anthropogenic origin is gradually increasing. As a tool to tackle this problem, carbazole derivatives are an attractive gateway to the development of luminescent chemosensors. Considering the...

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Biosensors - ISSN 2079-6374