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Biosensors, Volume 12, Issue 11

November 2022 - 148 articles

Cover Story: Type-I, -II and -III interferons (IFNs) are crucial for the first line of cell-intrinsic host defense. While type-I (IFNα, IFNβ) and type-III (IFNλs) induce transcription of interferon-stimulated genes (ISGs) via the JAK/STAT pathway, type-II IFN (IFNγ) is secreted by T helper type-1 cells and fuels the adaptive immune response to the pathogen. In addition, the airway epithelial barrier is important for the host cell intrinsic defense and orchestrates antiviral immune response by producing cytokines such as IL-33. Using a genome-wide gene expression biosensor chip sensing the gene expression in organotypic 3D air-liquid interface cultures, we were able to show that all types of IFNs induced similar ISGs. Type-I and type-III IFN stimulation positively correlated with the expression of cell–cell adhesion and intercellular signaling, and IFNγ promoted cell proliferation. View this paper
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Articles (148)

  • Article
  • Open Access
24 Citations
4,376 Views
12 Pages

21 November 2022

Beta-amyloid (βA) peptides accompanying the physiological change in brain induce Alzheimer’s disease. In this work, a highly sensitive electrochemical (EC) immunosensor platform has been developed for the quantitative detection of βA...

  • Article
  • Open Access
16 Citations
3,547 Views
12 Pages

Development of Ic-ELISA and Colloidal Gold Lateral Flow Immunoassay for the Determination of Cypermethrin in Agricultural Samples

  • Lianrun Huang,
  • Fuxuan Zhang,
  • Fangxuan Li,
  • Yin Jia,
  • Minghua Wang,
  • Xiude Hua and
  • Limin Wang

21 November 2022

Cypermethrin (CYP) is an insecticide in the pyrethroid family and is used widely in agriculture and for public health purposes. However, CYP has been shown to have negative impacts on reproduction, immunity and nerves in mammals. In this study, a mon...

  • Review
  • Open Access
27 Citations
6,665 Views
18 Pages

21 November 2022

Multifunctional wearable sensors and systems are of growing interest over the past decades because of real-time health monitoring and disease diagnosis capability. Owing to the tremendous efforts of scientists, wearable sensors and systems with attra...

  • Article
  • Open Access
8 Citations
2,949 Views
12 Pages

Dual Response Site Fluorescent Probe for Highly Sensitive Detection of Cys/Hcy and GSH In Vivo through Two Different Emission Channels

  • Huiling Hou,
  • Qi Liu,
  • Xiangbao Liu,
  • Shuang Fu,
  • Hongguang Zhang,
  • Shuang Li,
  • Song Chen and
  • Peng Hou

21 November 2022

Much research has demonstrated that metabolic imbalances of biothiols are closely associated with the emergence of different types of disease. In view of the significant effect of biothiols, quantitative evaluation and discrimination of intracellular...

  • Article
  • Open Access
4 Citations
3,278 Views
10 Pages

Mechanical Force-Induced Blue-Shifted and Enhanced Emission for AIEgens

  • Chang-Sheng Guo,
  • Xiao-Long Su,
  • Yu-Ting Yin,
  • Bo-Xuan Zhang,
  • Xin-Yi Liu,
  • Rui-Peng Wang,
  • Pu Chen,
  • Hai-Tao Feng and
  • Ben-Zhong Tang

21 November 2022

Mechanochromic (MC) luminescence of organic molecules has been emerging as a promising smart material for optical recording and memory devices. At the same time, pressure-induced blue-shifted and enhanced luminescence are rarely reported now. Herein,...

  • Review
  • Open Access
48 Citations
6,812 Views
26 Pages

21 November 2022

In the past two decades, biomimetic tactile sensing technology has been a hot spot in academia. It has prospective applications in many fields such as medical treatment, health monitoring, robot tactile feedback, and human–machine interaction....

  • Article
  • Open Access
9 Citations
2,876 Views
14 Pages

Dual-Wavelength Fluorescence Polarization Immunoassay for Simultaneous Detection of Sulfonamides and Antibacterial Synergists in Milk

  • Changfei Duan,
  • Yingjie Zhang,
  • Peipei Li,
  • Qiang Li,
  • Wenbo Yu,
  • Kai Wen,
  • Sergei A. Eremin,
  • Jianzhong Shen,
  • Xuezhi Yu and
  • Zhanhui Wang

21 November 2022

Combinations of sulfonamides (SAs) and antibacterial synergists (ASGs) are frequently used for treating infectious diseases and promoting growth for animals, which cause potential hazards to food safety and human health. To realize the simultaneous d...

  • Perspective
  • Open Access
5 Citations
3,139 Views
12 Pages

Future Prospects of Luminescent Silicon Nanowires Biosensors

  • Maria Josè Lo Faro,
  • Antonio Alessio Leonardi,
  • Francesco Priolo,
  • Barbara Fazio and
  • Alessia Irrera

21 November 2022

In this paper, we exploit the perspective of luminescent Si nanowires (NWs) in the growing field of commercial biosensing nanodevices for the selective recognition of proteins and pathogen genomes. We fabricated quantum confined fractal arrays of Si...

  • Article
  • Open Access
5 Citations
2,483 Views
10 Pages

Terahertz Biosensor Based on Mode Coupling between Defect Mode and Optical Tamm State with Dirac Semimetal

  • Yuwen Bao,
  • Mengjiao Ren,
  • Chengpeng Ji,
  • Jun Dong,
  • Leyong Jiang and
  • Xiaoyu Dai

21 November 2022

Bulk Dirac semimetal (BDS) has emerged as a “3D graphene” material for the development of optical devices in the past few years. In this study, a BDS-based tunable highly sensitive terahertz (THz) biosensor is proposed by using a Dirac se...

  • Article
  • Open Access
4 Citations
3,387 Views
11 Pages

Micro-Raman Analysis of Sperm Cells on Glass Slide: Potential Label-Free Assessment of Sperm DNA toward Clinical Applications

  • Shengrong Du,
  • Qun Zhang,
  • Haohao Guan,
  • Guannan Chen,
  • Sisi Wang,
  • Yan Sun,
  • Yuling Li,
  • Rong Chen,
  • Youwu He and
  • Zufang Huang

21 November 2022

Routine assessment of sperm DNA integrity involves the time-consuming and complex process of staining sperm chromatin. Here, we report a Raman spectroscopy method combined with extended multiplicative signal correction (EMSC) for the extraction of ch...

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Biosensors - ISSN 2079-6374