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Nanomaterials, Volume 15, Issue 16 (August-2 2025) – 2 articles

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19 pages, 741 KiB  
Review
Gold Nanoparticles for Wound Healing in Animal Models
by Stephen Klavsen and Sten Rasmussen
Nanomaterials 2025, 15(16), 1213; https://doi.org/10.3390/nano15161213 (registering DOI) - 8 Aug 2025
Abstract
Background: Gold nanoparticles (GNPs) are increasingly studied for their potential to enhance wound healing, but their overall efficacy remains uncertain. Methods: We conducted a systematic meta-analysis (search date: 14 May 2025) across five databases. Included were randomized animal studies comparing GNPs to placebo, [...] Read more.
Background: Gold nanoparticles (GNPs) are increasingly studied for their potential to enhance wound healing, but their overall efficacy remains uncertain. Methods: We conducted a systematic meta-analysis (search date: 14 May 2025) across five databases. Included were randomized animal studies comparing GNPs to placebo, reporting wound closure percentages and relevant variance measures. Risk of bias was assessed using Cochrane and CAMARADES tools. Cohen’s d was used to estimate effect size under a random-effects model. Results: Thirty-one studies met the inclusion criteria. The pooled effect size was d = 4.52 (95% CI: 3.61 to 5.43; z = 9.73; p < 0.001), indicating a significant benefit of GNPs. Although heterogeneity was moderate to high, results consistently favored GNPs. Conclusion: GNPs significantly accelerate wound healing in animal models, supporting their potential as therapeutic agents. Full article
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15 pages, 2944 KiB  
Article
High-Responsivity UV–Blue Photodetector Based on Nanostructured CdS and Prepared by Solution Processing
by Jian-Ru Lai, Fang-Hsing Wang, Han-Wen Liu and Tsung-Kuei Kang
Nanomaterials 2025, 15(16), 1212; https://doi.org/10.3390/nano15161212 - 8 Aug 2025
Abstract
Ultraviolet (UV) and blue-light photodetectors are vital in environmental monitoring, medical and biomedical applications, optical communications, and security and anti-counterfeiting technologies. However, conventional silicon-based devices suffer from limited sensitivity to short-wavelength light due to their narrow indirect bandgap. In this study, we investigate [...] Read more.
Ultraviolet (UV) and blue-light photodetectors are vital in environmental monitoring, medical and biomedical applications, optical communications, and security and anti-counterfeiting technologies. However, conventional silicon-based devices suffer from limited sensitivity to short-wavelength light due to their narrow indirect bandgap. In this study, we investigate the influence of precursor concentration on the structural, optical, and photoresponse characteristics of nanostructured CdS thin films synthesized via chemical bath deposition. Among the CdS samples prepared at different precursor concentrations, the best photoresponsivity of 21.1 mA/W was obtained at 2 M concentration. Subsequently, a p–n heterojunction photodetector was fabricated by integrating a spin-coated CuSCN layer with the optimized CdS nanostructure. The resulting device exhibited pronounced rectifying behavior with a rectification ratio of ~750 and an ideality factor of 1.39. Under illumination and a 5 V bias, the photodetector achieved an exceptional responsivity exceeding 104 A/W in the UV region—over six orders of magnitude higher than that of CdS-based metal–semiconductor–metal devices. This remarkable enhancement is attributed to the improved light absorption, efficient charge separation, and enhanced hole transport enabled by CuSCN incorporation and heterojunction formation. These findings present a cost-effective, solution-processed approach to fabricating high-responsivity nanostructured photodetectors, promising for future applications in smart healthcare, environmental surveillance, and consumer electronics. Full article
(This article belongs to the Section Nanoelectronics, Nanosensors and Devices)
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