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Journal of Functional Biomaterials, Volume 15, Issue 6

June 2024 - 33 articles

Cover Story: Several factors can necessitate delaying regenerative treatments for severe muscle trauma, including infection, management of comorbidities, and the time required for biomanufacturing of the therapeutics themselves. This study investigated using a polyvinyl alcohol-based, in situ-forming muscle void filler (MVF) to provide initial stabilization following volumetric muscle loss injury. These MVFs were removed after four weeks and replaced with minced muscle grafts to promote the regeneration of functional skeletal muscle within the defect. While this multi-stage approach effectively maintained the defect volume and minimized complications, the delayed application of MMGs did not demonstrate significant regenerative benefits. View this paper
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Articles (33)

  • Article
  • Open Access
12 Citations
5,479 Views
14 Pages

Comparison between Conventional and Digital Workflow in Implant Prosthetic Rehabilitation: A Randomized Controlled Trial

  • Massimo Corsalini,
  • Giuseppe Barile,
  • Francesco Ranieri,
  • Edvige Morea,
  • Tommaso Corsalini,
  • Saverio Capodiferro and
  • Rosario Roberto Palumbo

The progress of digital technologies in dental prosthodontics is fast and increasingly accurate, allowing practitioners to simplify their daily work. These technologies aim to substitute conventional techniques progressively, but their real efficienc...

  • Article
  • Open Access
2 Citations
1,738 Views
14 Pages

Laser Ablation Facilitates Implantation of Dynamic Self-Regenerating Cartilage for Articular Cartilage Regeneration

  • Yingfang Fan,
  • Fernando P. S. Guastaldi,
  • Gem Runyan,
  • Ying Wang,
  • William A. Farinelli,
  • Mark A. Randolph and
  • Robert W. Redmond

Objectives: This study investigated a novel strategy for improving regenerative cartilage outcomes. It combines fractional laser treatment with the implantation of neocartilage generated from autologous dynamic Self-Regenerating Cartilage (dSRC). Met...

  • Article
  • Open Access
6 Citations
2,660 Views
15 Pages

Analysis of Gingival Fibroblasts Behaviour in the Presence of 3D-Printed versus Milled Methacrylate-Based Dental Resins—Do We Have a Winner?

  • Veaceslav Saramet,
  • Miruna S. Stan,
  • Alexandra Ripszky Totan,
  • Ana Maria Cristina Țâncu,
  • Bianca Voicu-Balasea,
  • Dan Sebastian Enasescu,
  • Florentina Rus-Hrincu and
  • Marina Imre

Computer-aided design and computer-aided manufacturing (CAD/CAM) techniques are based on either subtractive (milling prefabricated blocks) or additive (3D printing) methods, and both are used for obtaining dentistry materials. Our in vitro study aime...

  • Article
  • Open Access
1 Citations
2,319 Views
12 Pages

Biocompatibility of Subperiosteal Dental Implants: Changes in the Expression of Osteogenesis-Related Genes in Osteoblasts Exposed to Differently Treated Titanium Surfaces

  • Marco Roy,
  • Elisa Chelucci,
  • Alessandro Corti,
  • Lorenzo Ceccarelli,
  • Mauro Cerea,
  • Barbara Dorocka-Bobkowska,
  • Alfonso Pompella and
  • Simona Daniele

The use of endosseous dental implants may become unfeasible in the presence of significant maxillary bone atrophy; thus, surgical techniques have been proposed to promote bone regeneration in such cases. However, such techniques are complex and may e...

  • Review
  • Open Access
14 Citations
5,346 Views
44 Pages

The management and reconstruction of critical-sized segmental bone defects remain a major clinical challenge for orthopaedic clinicians and surgeons. In particular, regenerative medicine approaches that involve incorporating stem cells within tissue...

  • Article
  • Open Access
1 Citations
3,806 Views
11 Pages

Effect of Bleaching Agents on Composite Resins with and without Bis-GMA: An In Vitro Study

  • María Melo,
  • Bianca Dumitrache,
  • James Ghilotti,
  • José Luis Sanz and
  • Carmen Llena

The objective was to evaluate the change in color, hardness, and roughness produced by carbamide peroxide (CP) at two different concentrations on two resins. The 16% or 45% CP was applied to 66 resin discs with and without Bis-GMA. The color was meas...

  • Article
  • Open Access
1 Citations
2,363 Views
14 Pages

Simulation of Orbital Fractures Using Experimental and Mathematical Approaches: A Pilot Study

  • Patrik Eiba,
  • Karel Frydrysek,
  • Behrad Zanganeh,
  • Daniel Cepica,
  • Pavel Marsalek,
  • Petr Handlos,
  • Juraj Timkovic,
  • Jan Stembirek,
  • Jakub Cienciala and
  • Arnost Onderka
  • + 2 authors

This contribution gives basic information about the mechanical behavior of the facial part of the human skull cranium, i.e., the splanchnocranium, associated with external loads and injuries caused mainly by brachial violence. The main areas sufferin...

  • Article
  • Open Access
3 Citations
1,791 Views
14 Pages

Induction of Apoptosis with Silver Nanoparticles Obtained Using Thermophilic Bacteria

  • Kotryna Čekuolytė,
  • Diana Šapaitė,
  • Estera Žemgulytė,
  • Renata Gudiukaitė and
  • Eglė Lastauskienė

Yeasts resistant to antifungals have become an increasing risk to human health. One of the best antimicrobial properties is reported to be present in silver nanoparticles (AgNPs); however, little is known about the antimicrobial potential of AgNPs pr...

  • Article
  • Open Access
4 Citations
2,474 Views
22 Pages

Elasticity Modification of Biomaterials Used in 3D Printing with an Elastin–Silk-like Recombinant Protein

  • Violetta Cecuda-Adamczewska,
  • Agnieszka Romanik-Chruścielewska,
  • Katarzyna Kosowska,
  • Iwona Sokołowska,
  • Natalia Łukasiewicz,
  • Paulina Korycka,
  • Katarzyna Florys-Jankowska,
  • Agnieszka Zakrzewska,
  • Michał Wszoła and
  • Marta Klak

The recombinant structural protein described in this study was designed based on sequences derived from elastin and silk. Silk–elastin hybrid copolymers are characterized by high solubility while maintaining high product flexibility. The phase...

  • Article
  • Open Access
5 Citations
2,172 Views
14 Pages

Tissue engineering aims to develop bionic scaffolds as alternatives to autologous vascular grafts due to their limited availability. This study introduces a novel wet-electrospinning fabrication technique to create small-diameter, uniformly aligned t...

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J. Funct. Biomater. - ISSN 2079-4983