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Journal of Functional Biomaterials, Volume 15, Issue 6

June 2024 - 33 articles

Cover Story: Several factors can necessitate delaying regenerative treatments for severe muscle trauma, including infection, management of comorbidities, and the time required for biomanufacturing of the therapeutics themselves. This study investigated using a polyvinyl alcohol-based, in situ-forming muscle void filler (MVF) to provide initial stabilization following volumetric muscle loss injury. These MVFs were removed after four weeks and replaced with minced muscle grafts to promote the regeneration of functional skeletal muscle within the defect. While this multi-stage approach effectively maintained the defect volume and minimized complications, the delayed application of MMGs did not demonstrate significant regenerative benefits. View this paper
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Articles (33)

  • Review
  • Open Access
3 Citations
2,140 Views
20 Pages

Endogenous peptides, particularly those with post-translational modifications, are increasingly being studied as biomarkers for diagnosing various diseases. However, they are weakly ionizable, have a low abundance in biological samples, and may be in...

  • Article
  • Open Access
1,766 Views
12 Pages

In Vitro/Ex Vivo Release Study of a Ground Umbilical Cord Matrix Loaded with Dexamethasone

  • Florine Grossetete,
  • Charlotte Garot,
  • Emmanuel Crouzet,
  • Xavier Delavenne,
  • Philippe Gain,
  • Laurence Barnouin and
  • Gilles Thuret

Eye drops containing steroids and antibiotics are widely used to treat a large range of ocular diseases of the ocular surface. They require frequent instillation or a high dosage, which can affect quality of life. We developed a biomaterial from huma...

  • Article
  • Open Access
5 Citations
2,423 Views
12 Pages

Background: The advent of three-dimensional (3D) printing technology has revolutionized the field of dentistry, enabling the precise fabrication of dental implants. By utilizing 3D printing, dentists can devise implant plans prior to surgery and accu...

  • Article
  • Open Access
3 Citations
1,872 Views
14 Pages

Innovative Bioactive Ca-SZ Coating on Titanium Dental Implants: A Multidimensional Structural and Elemental Analysis

  • Alex Tchinda,
  • Aurélien Didelot,
  • Patrick Choquet,
  • Augustin Lerebours,
  • Richard Kouitat-Njiwa and
  • Pierre Bravetti

The design of new, biomimetic biomaterials is of great strategic interest and is converging for many applications, including in implantology. This study explores a novel approach to improving dental implants. Although endosseous TA6V alloy dental imp...

  • Article
  • Open Access
1 Citations
2,855 Views
14 Pages

Functionalized Surface Coatings for Rigid Contact Lenses

  • Roeya Refaei,
  • Kyueui Lee,
  • Goun Amy Lee,
  • Paul Demian,
  • Fouad El Mansouri,
  • Phillip B. Messersmith,
  • Mouad Lamrani,
  • Mohamed Khaddor and
  • Nabil Allali

This research evolves into a comparative study of three different phenolic composites as coatings for rigid contact lenses, with a particular emphasis on enhancing their antifouling properties and hydrophobicity. The primary layer, comprised of diver...

  • Article
  • Open Access
3 Citations
2,630 Views
13 Pages

Evidence of Lysosomal β-Hexosaminidase Enzymatic Activity Associated with Extracellular Vesicles: Potential Applications for the Correction of Sandhoff Disease

  • Eleonora Calzoni,
  • Giada Cerrotti,
  • Krizia Sagini,
  • Federica Delo,
  • Sandra Buratta,
  • Roberto Maria Pellegrino,
  • Husam B. R. Alabed,
  • Federica Fratini,
  • Carla Emiliani and
  • Lorena Urbanelli

Extracellular vesicles (EVs) can be isolated from biological fluids and cell culture medium. Their nanometric dimension, relative stability, and biocompatibility have raised considerable interest for their therapeutic use as delivery vehicles of macr...

  • Article
  • Open Access
3 Citations
2,366 Views
14 Pages

Silver nanoparticles (AgNPs) are known for their antibacterial properties and their ability to promote wound healing. By incorporating silver nanoparticles into medical gauze, the resulting composite material shows promise as an advanced wound dressi...

  • Systematic Review
  • Open Access
2 Citations
2,974 Views
16 Pages

Unlocking the Future: Bioprinting Salivary Glands—From Possibility to Reality

  • Dobromira Shopova,
  • Antoniya Yaneva,
  • Anna Mihaylova,
  • Atanaska Dinkova and
  • Desislava Bakova

Salivary gland biofabrication represents a promising avenue in regenerative medicine, aiming to address the challenges of salivary gland dysfunction caused by various factors such as autoimmune diseases and radiotherapy. This review examines the curr...

  • Review
  • Open Access
4 Citations
3,552 Views
23 Pages

Bone defects resulting from trauma, surgery, and congenital, infectious, or oncological diseases are a functional and aesthetic burden for patients. Bone regeneration is a demanding procedure, involving a spectrum of molecular processes and requiring...

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J. Funct. Biomater. - ISSN 2079-4983