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Journal of Functional Biomaterials, Volume 11, Issue 3

September 2020 - 22 articles

Cover Story: Over millions of years, nature has produced a wide variety of biological materials optimised for distinct functions. Many of these systems found in biology possess unique surface properties recognised to regulate cell behaviour. Integration of such natural surface properties in biomaterials can bring about novel cell responses and provide greater insights into the processes occurring at the cell–biomaterial interface. Using natural surfaces as templates for bioinspired design can stimulate progress in the field of regenerative medicine, tissue engineering and biomaterials science. This literature review aims to combine the state-of-the-art knowledge in natural and nature-inspired surfaces. View this paper
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Articles (22)

  • Review
  • Open Access
205 Citations
15,632 Views
36 Pages

Bio-Based Electrospun Fibers for Wound Healing

  • Bahareh Azimi,
  • Homa Maleki,
  • Lorenzo Zavagna,
  • Jose Gustavo De la Ossa,
  • Stefano Linari,
  • Andrea Lazzeri and
  • Serena Danti

22 September 2020

Being designated to protect other tissues, skin is the first and largest human body organ to be injured and for this reason, it is accredited with a high capacity for self-repairing. However, in the case of profound lesions or large surface loss, the...

  • Article
  • Open Access
18 Citations
4,069 Views
20 Pages

Biosynthesis, Characterization, and Biological Activities of Procyanidin Capped Silver Nanoparticles

  • Umar M. Badeggi,
  • Jelili A. Badmus,
  • Subelia S. Botha,
  • Enas Ismail,
  • Jeanine L. Marnewick,
  • Charlene W. J. Africa and
  • Ahmed A. Hussein

19 September 2020

In this study, procyanidin dimers and Leucosidea sericea total extract (LSTE) were employed in the synthesis of silver nanoparticles (AgNPs) and characterized by ultraviolet-visible (UV-Visible) spectroscopy, high-resolution transmission electron mic...

  • Article
  • Open Access
11 Citations
3,081 Views
12 Pages

Development of Bionanocomposites Based on Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate)/PolylActide Blends Reinforced with Cloisite 30B

  • Clément Lacoste,
  • Benjamin Gallard,
  • José-Marie Lopez-Cuesta,
  • Ozlem Ipek Kalaoglu-Altan and
  • Karen De Clerck

16 September 2020

In the present study, poly(3-hydroxybuturate-co-3-hydroxyvalerate) (PHBV) and plasticized polylactide acid (PLA) blends were processed by melt extrusion with different weight ratio (up to 20 wt.% of PHBV). Bionanocomposites were obtained through the...

  • Article
  • Open Access
13 Citations
4,766 Views
13 Pages

Biocompatibility of α-Al2O3 Ceramic Substrates with Human Neural Precursor Cells

  • Akrivi Asimakopoulou,
  • Ioannis Gkekas,
  • Georgia Kastrinaki,
  • Alessandro Prigione,
  • Vasileios T. Zaspalis and
  • Spyros Petrakis

16 September 2020

Background: Biocompatible materials-topography could be used for the construction of scaffolds allowing the three-dimensional (3D) organization of human stem cells into functional tissue-like structures with a defined architecture. Methods: Structura...

  • Article
  • Open Access
18 Citations
4,730 Views
30 Pages

Carbonate Apatite and Hydroxyapatite Formulated with Minimal Ingredients to Deliver SiRNA into Breast Cancer Cells In Vitro and In Vivo

  • Rowshan Ara Islam,
  • Hamed Al-Busaidi,
  • Rahela Zaman,
  • Syafiq Asnawi Zainal Abidin,
  • Iekhsan Othman and
  • Ezharul Hoque Chowdhury

10 September 2020

Introduction: Cancer is one of the top-ranked noncommunicable diseases causing deaths to nine million people and affecting almost double worldwide in 2018. Tremendous advancement in surgery, chemotherapy, radiation and targeted immunotherapy have imp...

  • Article
  • Open Access
55 Citations
6,906 Views
17 Pages

Electrosprayed Chitin Nanofibril/Electrospun Polyhydroxyalkanoate Fiber Mesh as Functional Nonwoven for Skin Application

  • Bahareh Azimi,
  • Lily Thomas,
  • Alessandra Fusco,
  • Ozlem Ipek Kalaoglu-Altan,
  • Pooja Basnett,
  • Patrizia Cinelli,
  • Karen De Clerck,
  • Ipsita Roy,
  • Giovanna Donnarumma and
  • Maria-Beatrice Coltelli
  • + 2 authors

Polyhydroxyalkanoates (PHAs) are a family of bio-based polyesters that have found different biomedical applications. Chitin and lignin, byproducts of fishery and plant biomass, show antimicrobial and anti-inflammatory activity on the nanoscale. Due t...

  • Article
  • Open Access
17 Citations
4,238 Views
9 Pages

Collagen films with proton conduction are a candidate of next generation of fuel-cell electrolyte. To clarify a relation between proton conductivity and formation of water networks in the collagen film originating from a tilapia’s scale, we sys...

  • Article
  • Open Access
28 Citations
4,525 Views
13 Pages

Antimicrobial Properties of the Polyaniline Composites against Pseudomonas aeruginosa and Klebsiella pneumoniae

  • Moorthy Maruthapandi,
  • Arumugam Saravanan,
  • John H. T. Luong and
  • Aharon Gedanken

CuO, TiO2, or SiO2 was decorated on polyaniline (PANI) by a sonochemical method, and their antimicrobial properties were investigated for two common Gram-negative pathogens: Pseudomonas aeruginosa (PA) and Klebsiella pneumoniae (KP). Without PANI, Cu...

  • Feature Paper
  • Review
  • Open Access
37 Citations
8,024 Views
20 Pages

Biodegradable Polymeric Micro/Nano-Structures with Intrinsic Antifouling/Antimicrobial Properties: Relevance in Damaged Skin and Other Biomedical Applications

  • Mario Milazzo,
  • Giuseppe Gallone,
  • Elena Marcello,
  • Maria Donatella Mariniello,
  • Luca Bruschini,
  • Ipsita Roy and
  • Serena Danti

Bacterial colonization of implanted biomedical devices is the main cause of healthcare-associated infections, estimated to be 8.8 million per year in Europe. Many infections originate from damaged skin, which lets microorganisms exploit injuries and...

  • Article
  • Open Access
33 Citations
5,325 Views
17 Pages

Electrospun Scaffolds Containing Silver-Doped Hydroxyapatite with Antimicrobial Properties for Applications in Orthopedic and Dental Bone Surgery

  • Thomas E. Paterson,
  • Rui Shi,
  • Jingjing Tian,
  • Caroline J. Harrison,
  • Mailys De Sousa Mendes,
  • Paul V. Hatton,
  • Zhou Li and
  • Ilida Ortega

Preventing the development of osteomyelitis while enhancing bone regeneration is challenging, with relatively little progress to date in translating promising technologies to the clinic. Nanoscale hydroxyapatite (nHA) has been employed as a bone graf...

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J. Funct. Biomater. - ISSN 2079-4983Creative Common CC BY license