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Journal of Functional Biomaterials, Volume 11, Issue 2

2020 June - 25 articles

Cover Story: Ag- and Cu-incorporated TiO2 layers were incubated in saline for a period of 0–28 days, and both the durability of the antibacterial effect and surface changes were investigated. As a result, the chemical state of Ag changed from Ag2O to metallic Ag, whilst that of Cu did not change. The concentrations of Ag and Cu were dramatically decreased by incubation. The antibacterial effect of Ag-incorporated specimens diminished, and that of Cu was maintained even after incubation in saline. Our study suggests the importance of time-transient effects of Ag and Cu on the development of antibacterial effects. View this paper
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Articles (25)

  • Article
  • Open Access
11 Citations
5,023 Views
16 Pages

Evaluation of the In Vivo Biocompatibility of Amorphous Calcium Phosphate-Containing Metals

  • Pio Moerbeck-Filho,
  • Suelen C. Sartoretto,
  • Marcelo J. Uzeda,
  • Maurício Barreto,
  • Alena Medrado,
  • Adriana Alves and
  • Mônica D. Calasans-Maia

Among the biomaterials based on calcium phosphate, hydroxyapatite has been widely used due to its biocompatibility and osteoconduction. The substitution of the phosphate group by the carbonate group associated with the absence of heat treatment and l...

  • Article
  • Open Access
28 Citations
4,819 Views
11 Pages

Time-Transient Effects of Silver and Copper in the Porous Titanium Dioxide Layer on Antibacterial Properties

  • Masaya Shimabukuro,
  • Akari Hiji,
  • Tomoyo Manaka,
  • Kosuke Nozaki,
  • Peng Chen,
  • Maki Ashida,
  • Yusuke Tsutsumi,
  • Akiko Nagai and
  • Takao Hanawa

Recently, silver (Ag) and copper (Cu) have been incorporated into a titanium (Ti) surface to realize their antibacterial property. This study investigated both the durability of the antibacterial effect and the surface change of the Ag- and Cu-incorp...

  • Article
  • Open Access
23 Citations
5,372 Views
9 Pages

Novel Coatings to Minimize Bacterial Adhesion and Promote Osteoblast Activity for Titanium Implants

  • Samira E. A. Camargo,
  • Tanaya Roy,
  • Patrick H. Carey IV,
  • Chaker Fares,
  • Fan Ren,
  • Arthur E. Clark and
  • Josephine F. Esquivel-Upshaw

Titanium nitride (TiN) and silicon carbide (SiC) adhesion properties to biofilm and the proliferation of human osteoblasts were studied. Quaternized titanium nitride (QTiN) was produced by converting the surface nitrogen on TiN to a positive charge t...

  • Article
  • Open Access
12 Citations
4,353 Views
19 Pages

CaSiO3-HAp Structural Bioceramic by Sol-Gel and SPS-RS Techniques: Bacteria Test Assessment

  • Evgeniy Papynov,
  • Oleg Shichalin,
  • Igor Buravlev,
  • Anton Belov,
  • Arseniy Portnyagin,
  • Vitaliy Mayorov,
  • Evgeniy Merkulov,
  • Taisiya Kaidalova,
  • Yulia Skurikhina and
  • Vladimir Apanasevich
  • + 2 authors

The article presents an original way of getting porous and mechanically strong CaSiO3-HAp ceramics, which is highly desirable for bone-ceramic implants in bone restoration surgery. The method combines wet and solid-phase approaches of inorganic synth...

  • Review
  • Open Access
12 Citations
5,550 Views
41 Pages

On the Interaction between 1D Materials and Living Cells

  • Giuseppe Arrabito,
  • Yana Aleeva,
  • Vittorio Ferrara,
  • Giuseppe Prestopino,
  • Clara Chiappara and
  • Bruno Pignataro

One-dimensional (1D) materials allow for cutting-edge applications in biology, such as single-cell bioelectronics investigations, stimulation of the cellular membrane or the cytosol, cellular capture, tissue regeneration, antibacterial action, tracti...

  • Article
  • Open Access
4 Citations
4,012 Views
16 Pages

A 2,5-Dihydroxybenzoic Acid–Gelatin Conjugate Inhibits the Basal and Hsp90-Stimulated Migration and Invasion of Tumor Cells

  • Anastasiya V. Snigireva,
  • Oleg S. Morenkov,
  • Yuri Y. Skarga,
  • Alexander V. Lisov,
  • Zoya A. Lisova,
  • Alexey A. Leontievsky,
  • Mariya A. Zhmurina,
  • Viktoria S. Petrenko and
  • Veronika V. Vrublevskaya

The extracellular cell surface-associated and soluble heat shock protein 90 (Hsp90) is known to participate in the migration and invasion of tumor cells. Earlier, we demonstrated that plasma membrane-associated heparan sulfate proteoglycans (HSPGs) b...

  • Communication
  • Open Access
14 Citations
5,129 Views
10 Pages

This communication reports preliminary data towards the development of a live ex vivo model of persistent infection that is based on the chick embryo chorioallantoic membrane (CAM), which can be used for pre-screening biomaterials with antimicrobial...

  • Article
  • Open Access
12 Citations
6,246 Views
11 Pages

Bioactive mineral-based dentin desensitizers that can quickly and effectively seal dentinal tubules and promote dentin mineralization are desired. This in vitro study evaluated a novel nanohydroxyapatite-based desensitizer, Predicta (PBD, Parkell), a...

  • Article
  • Open Access
5 Citations
4,729 Views
13 Pages

Bioactive glass (BG) nanoparticles have wide applications in bone repair due to their bone-bonding and biodegradable nature. In this work, nanometric rod-shaped ternary SiO2-CaO-P2O5 bioactive glass particles were prepared through sol-gel chemistry f...

  • Article
  • Open Access
34 Citations
7,084 Views
17 Pages

Substituted Nano-Hydroxyapatite Toothpastes Reduce Biofilm Formation on Enamel and Resin-Based Composite Surfaces

  • Andrei C. Ionescu,
  • Gloria Cazzaniga,
  • Marco Ottobelli,
  • Franklin Garcia-Godoy and
  • Eugenio Brambilla

Background: Toothpastes containing nano-hydroxyapatite (n-HAp) substituted with metal ions provide calcium and phosphate ions to dental hard tissues, reducing demineralization, and promoting remineralization. Few data are available about the effect o...

  • Article
  • Open Access
13 Citations
6,196 Views
12 Pages

Coating Medpor® Implant with Tissue-Engineered Elastic Cartilage

  • Dong Joon Lee,
  • Jane Kwon,
  • Yong-Il Kim,
  • Yong Hoon Kwon,
  • Samuel Min and
  • Hae Won Shin

Inert biomaterials used for auricular reconstruction, which is one of the most challenging and diverse tasks in craniofacial or head and neck surgery, often cause problems such as capsule formation, infection, and skin extrusion. To solve these probl...

  • Article
  • Open Access
8 Citations
5,319 Views
16 Pages

Chitin Lignin nanoparticles (CN-NL), standalone and encapsulating glycyrrhetic acid (GA), were applied on novel substrates for textiles to obtain antibacterial, antioxidant properties. Their homogeneous application is an important parameter that can...

  • Article
  • Open Access
27 Citations
6,275 Views
13 Pages

Anti-Bacterial Properties and Biocompatibility of Novel SiC Coating for Dental Ceramic

  • Samira Esteves Afonso Camargo,
  • Azeem S. Mohiuddeen,
  • Chaker Fares,
  • Jessica L. Partain,
  • Patrick H. Carey,
  • Fan Ren,
  • Shu-Min Hsu,
  • Arthur E. Clark and
  • Josephine F. Esquivel-Upshaw

A 200 nm plasma-enhanced chemical vapor-deposited SiC was used as a coating on dental ceramics to improve anti-bacterial properties for the applications of dental prosthesis. A thin SiO2 (20 nm) in the same system was deposited first, prior to SiC de...

  • Review
  • Open Access
23 Citations
7,748 Views
13 Pages

Autologous Matrix of Platelet-Rich Fibrin in Wound Care Settings: A Systematic Review of Randomized Clinical Trials

  • Chayane Karla Lucena de Carvalho,
  • Beatriz Luci Fernandes and
  • Mauren Abreu de Souza

Platelet-rich fibrin (PRF) consists of a matrix that provides the necessary elements for wound healing, acting as a biodegradable scaffold for cell migration, proliferation, and differentiation, in addition to the delivery of growth factors and angio...

  • Article
  • Open Access
24 Citations
6,298 Views
16 Pages

Modification of PLA-Based Films by Grafting or Coating

  • Aleksandra Miletić,
  • Ivan Ristić,
  • Maria-Beatrice Coltelli and
  • Branka Pilić

Recently, the demand for the use of natural polymers in the cosmetic, biomedical, and sanitary sectors has been increasing. In order to meet specific functional properties of the products, usually, the incorporation of the active component is require...

  • Review
  • Open Access
29 Citations
6,534 Views
16 Pages

Background: Different augmentation techniques have been described in the literature in addition to the surgical treatment of proximal humeral fractures. The aim of this systematic review was to analyze the use of cements, bone substitutes, and other...

  • Article
  • Open Access
13 Citations
4,500 Views
11 Pages

We investigated the effect of helium atmospheric-pressure plasma (PL) and deep-ultraviolet (UV) light treatments on the adhesive properties of fiber-reinforced poly(ether-ether-ketone) polymer (PEEK). PEEK disks reinforced with carbon (CPEEK) or glas...

  • Article
  • Open Access
4 Citations
4,331 Views
13 Pages

Open-Cell Tizr-Based Bulk Metallic Glass Scaffolds with Excellent Biocompatibility and Suitable Mechanical Properties for Biomedical Application

  • Van Tai Nguyen,
  • Xavier Pei-Chun Wong,
  • Sin-Mao Song,
  • Pei-Hua Tsai,
  • Jason Shian-Ching Jang,
  • I-Yu Tsao,
  • Che-Hsin Lin and
  • Van Cuong Nguyen

A series of biocompatible high-porosity (up to 72.4%) TiZr-based porous bulk metallic glass (BMG) scaffolds were successfully fabricated by hot pressing a mixture of toxic element-free TiZr-based BMG powder and an Al particle space holder. The morpho...

  • Communication
  • Open Access
15 Citations
5,102 Views
11 Pages

Clinoenstatite/Tantalum Coating for Enhancement of Biocompatibility and Corrosion Protection of Mg Alloy

  • Hamid Reza Bakhsheshi-Rad,
  • Aliakbar Najafinezhad,
  • Esah Hamzah,
  • Ahmad Fauzi Ismail,
  • Filippo Berto and
  • Xiongbiao Chen

Biodegradable Mg alloys have appeared as the most appealing metals for biomedical applications, particularly as temporary bone implants. However, issues regarding high corrosion rate and biocompatibility restrict their application. Hence, in the pres...

  • Article
  • Open Access
35 Citations
6,782 Views
14 Pages

Antimicrobial Materials with Lime Oil and a Poly(3-hydroxyalkanoate) Produced via Valorisation of Sugar Cane Molasses

  • Pooja Basnett,
  • Elena Marcello,
  • Barbara Lukasiewicz,
  • Rinat Nigmatullin,
  • Alexandra Paxinou,
  • Muhammad Haseeb Ahmad,
  • Bhavana Gurumayum and
  • Ipsita Roy

A medium chain-length polyhydroxyalkanoate (PHA) was produced by Pseudomonas mendocina CH50 using a cheap carbon substrate, sugarcane molasses. A PHA yield of 14.2% dry cell weight was achieved. Chemical analysis confirmed that the polymer produced w...

  • Review
  • Open Access
28 Citations
8,380 Views
18 Pages

The Role of Poly(Methyl Methacrylate) in Management of Bone Loss and Infection in Revision Total Knee Arthroplasty: A Review

  • Leyla Hasandoost,
  • Omar Rodriguez,
  • Adel Alhalawani,
  • Paul Zalzal,
  • Emil H. Schemitsch,
  • Stephen D. Waldman,
  • Marcello Papini and
  • Mark R. Towler

Poly(methyl methacrylate) (PMMA) is widely used in joint arthroplasty to secure an implant to the host bone. Complications including fracture, bone loss and infection might cause failure of total knee arthroplasty (TKA), resulting in the need for rev...

  • Article
  • Open Access
35 Citations
7,793 Views
20 Pages

Skin-Compatible Biobased Beauty Masks Prepared by Extrusion

  • Maria-Beatrice Coltelli,
  • Luca Panariello,
  • Pierfrancesco Morganti,
  • Serena Danti,
  • Adone Baroni,
  • Andrea Lazzeri,
  • Alessandra Fusco and
  • Giovanna Donnarumma

In the cosmetic sector, natural and sustainable products with a high compatibility with skin, thus conjugating wellness with a green-oriented consumerism, are required by the market. Poly(hydroxyalkanoate) (PHA)/starch blends represent a promising al...

  • Article
  • Open Access
84 Citations
9,244 Views
17 Pages

Cytotoxic Effects of Plant Sap-Derived Extracellular Vesicles on Various Tumor Cell Types

  • Kimin Kim,
  • Hye Ju Yoo,
  • Jik-Han Jung,
  • Ruri Lee,
  • Jae-Kyung Hyun,
  • Ji-Ho Park,
  • Dokyun Na and
  • Ju Hun Yeon

Edible plants have been widely used in traditional therapeutics because of the biological activities of their natural ingredients, including anticancer, antioxidant, and anti-inflammatory properties. Plant sap contains such medicinal substances and t...

  • Article
  • Open Access
42 Citations
7,558 Views
23 Pages

Properties and Skin Compatibility of Films Based on Poly(Lactic Acid) (PLA) Bionanocomposites Incorporating Chitin Nanofibrils (CN)

  • Maria-Beatrice Coltelli,
  • Laura Aliotta,
  • Alessandro Vannozzi,
  • Pierfrancesco Morganti,
  • Luca Panariello,
  • Serena Danti,
  • Simona Neri,
  • Cristina Fernandez-Avila,
  • Alessandra Fusco and
  • Andrea Lazzeri
  • + 1 author

Nanobiocomposites suitable for preparing skin compatible films by flat die extrusion were prepared by using plasticized poly(lactic acid) (PLA), poly(butylene succinate-co-adipate) (PBSA), and Chitin nanofibrils as functional filler. Chitin nanofibri...

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J. Funct. Biomater. - ISSN 2079-4983