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Journal of Clinical Medicine, Volume 13, Issue 22

November-2 2024 - 373 articles

Cover Story: Patients with neck metastasis and no obvious primary tumor (NCUP) pose a diagnostic challenge. Many of these cases are p16-positive oropharyngeal squamous cell carcinomas (OPSCCs), often originating in the tonsils or base of the tongue. Early neck metastasis is likely due to the unique anatomy of the oropharynx. Identifying the primary tumor is crucial for treatment planning. However, imaging studies may not always be definitive. HPV testing can help localize the primary tumor, particularly in the oropharynx. Careful consideration of clinical, biomolecular, and morphological factors is essential for accurate prognosis and treatment, especially in HPV-positive patients with tobacco exposure or p53 mutations. View this paper
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Articles (373)

  • Article
  • Open Access
2 Citations
2,590 Views
8 Pages

20 November 2024

Background: Extremity fractures are common injuries in polytraumatized patients. Concomitant injuries to the soft tissue, vessels and nerves in these fractures are defined as mangled extremities. The decision for or against limb salvage is dependent...

  • Article
  • Open Access
1 Citations
2,815 Views
11 Pages

Comparative Effect of Insulin Resistance Reduction and Hormonal Alterations on Type 2 Diabetes Remission After Bariatric Surgery

  • Ekaterina Shestakova,
  • Iurii Stafeev,
  • Yury Yashkov,
  • Anatoly Yurasov,
  • Alina Tomilova,
  • Yelena Parfyonova,
  • Marina Shestakova and
  • Ivan Dedov

20 November 2024

Background: Bariatric surgery is known to induce weight loss and diabetes remission in patients with type 2 diabetes (T2D), but the exact mechanism of glycemic normalization needs to be defined. Methods: The study included patients with BMI ≥ 35 k...

  • Article
  • Open Access
6 Citations
2,950 Views
15 Pages

Two-Year Outcomes Using Fast-Acting, Sub-Perception Therapy for Spinal Cord Stimulation: A European, Real-World, Multicenter Experience

  • Simon Bayerl,
  • Jose Paz-Solis,
  • Georgios Matis,
  • Philippe Rigoard,
  • Jan Willem Kallewaard,
  • M. Angeles Canos-Verdecho,
  • Jan Vesper,
  • Jose Emilio Llopis,
  • Georgios Kyriakopoulos and
  • Ashish Gulve
  • + 4 authors

20 November 2024

Background/Objectives: Over the last 20 years, spinal cord stimulation (SCS) has seen the development of various paresthesia-free paradigms. Recently, a novel modality has emerged (Fast-Acting Sub-perception Therapy, FAST) that engages the surroundin...

  • Systematic Review
  • Open Access
1 Citations
1,664 Views
11 Pages

Effect of Cochlear Implantation on Air Conduction and Bone Conduction Elicited Vestibular Evoked Myogenic Potentials—A Scoping Review

  • Muhammed Ayas,
  • Jameel Muzaffar,
  • Veronica Phillips,
  • Mathew E. Smith,
  • Daniele Borsetto and
  • Manohar L. Bance

20 November 2024

Background/Objectives: Cochlear implantation (CI) is an effective intervention for individuals with severe to profound hearing loss; however, it may impact vestibular function due to its proximity to related anatomical structures. Vestibular evoked m...

  • Review
  • Open Access
1 Citations
1,734 Views
15 Pages

20 November 2024

Physical activity (PA) provides great health benefits for people with spinal cord injury (SCI). Consequently, the design and implementation of PA interventions addressed to this population is needed. To rigorously evaluate these interventions, the us...

  • Review
  • Open Access
2,038 Views
13 Pages

20 November 2024

Significant advances in the diagnosis and treatment of congenital heart disease have transformed patient outcomes, leading to an expanding adult congenital heart disease population. Many of these adults require lifelong procedural interventions, freq...

  • Feature Paper
  • Article
  • Open Access
2 Citations
1,630 Views
20 Pages

Evaluating a New Short Self-Management Tool in Heart Failure Against the Traditional Flinders Program

  • Pupalan Iyngkaran,
  • David Smith,
  • Craig McLachlan,
  • Malcolm Battersby,
  • Maximilian de Courten and
  • Fahad Hanna

20 November 2024

Background/Objective: Heart failure (HF) is a complex syndrome, with multiple causes. Numerous pathophysiological pathways are activated. Comprehensive and guideline-derived care is complex. A multidisciplinary approach is required. The current guide...

  • Review
  • Open Access
4 Citations
7,660 Views
20 Pages

Non-Pharmacological Therapy in Heart Failure and Management of Heart Failure in Special Populations—A Review

  • Jasmine K. Dugal,
  • Arpinder S. Malhi,
  • Noyan Ramazani,
  • Brianna Yee,
  • Michael V. DiCaro and
  • KaChon Lei

20 November 2024

Non-pharmacological therapies play an essential role in the management of heart failure, complementing pharmacological treatments to mitigate disease progression and improve patient outcomes. This review provides an updated perspective on non-pharmac...

  • Article
  • Open Access
992 Views
8 Pages

Late-Onset Femoroacetabular Impingement Syndrome Following Knee Arthroscopy in a Retrospective Cohort

  • Nicole D. Rynecki,
  • Matthew T. Kingery,
  • Rachel Roller,
  • Emily Berzolla,
  • Christopher A. Colasanti and
  • Thomas Youm

20 November 2024

Background/Objectives: Hip–knee coupling is a well-documented phenomenon, and interventions to one joint can alter biomechanics at the other. The purpose of this study was to investigate if knee surgery is associated with later onset of femoroa...

  • Article
  • Open Access
2 Citations
1,628 Views
11 Pages

Echocardiographic Screening of Liver Transplant Candidates—Prevalence of Features of Portopulmonary Hypertension

  • Olga Dzikowska-Diduch,
  • Tomasz Cader,
  • Krzysztof Jankowski,
  • Aisha Ou-Pokrzewińska,
  • Monika Sznajder,
  • Jan Siwiec,
  • Szymon Pucyło,
  • Aleksandra Sikora,
  • Marek Pacholczyk and
  • Wojciech Lisik
  • + 2 authors

20 November 2024

Background: The prevalence of portopulmonary hypertension (PoPH) is relatively low; however, its presence significantly worsens patients’ prognosis. When diagnosed, PoPH can be effectively treated, and specific therapies can lead to a substanti...

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J. Clin. Med. - ISSN 2077-0383