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Vaccines, Volume 9, Issue 12

2021 December - 137 articles

Cover Story: The scarcity of alternative therapeutics against viral infections as efficient as vaccines makes them essential in such areas as animal care. Whole-pathogen inactivated vaccines present substantial biosafety and handling advantages and thus a higher market acceptance in the animal production industry, including in aquaculture. Viral nervous necrosis (VNN) caused by the nervous necrosis virus (NNV) affects a broad range of primarily marine fish species, with mass mortality rates among larvae and juveniles. Its genetic diversification may hinder the effective implementation of vaccines. The present study describes different rapid inactivation procedures for developing an inactivated vaccine against a new NNV isolate confirmed to possess deadly effects upon the European seabass (Dicentrarchus labrax), an important farmed fish species. View this paper
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Vaccines - ISSN 2076-393X
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