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Vaccines, Volume 13, Issue 3
March 2025 - 127 articles
Cover Story: Bovine respiratory syncytial virus (BRSV) is a major pathogen in calves, responsible for severe respiratory outbreaks. Its high mutation rate leads to genetic diversity, potentially affecting vaccine efficacy. In this study, we identified strains from subgroups II and VIII circulating in Wallonia, Belgium, with subgroup VIII being documented for the first time in the country. Current vaccines are based on strains from subgroups II and III, raising questions about their effectiveness, particularly against subgroup VIII. The continuous evolution of BRSV highlights the need for sustained surveillance to guide vaccine strategies. Given its widespread distribution, monitoring viral diversity in other countries is crucial for effective disease control. View this paper
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Vaccines - ISSN 2076-393X