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Vaccines, Volume 12, Issue 3

2024 March - 124 articles

Cover Story: Nucleic acid vaccines (i.e., viral vectors, DNA vaccines and mRNA vaccines) provide multiple advantages over other vaccine platforms like subunit proteins or whole-pathogen vaccines. As demonstrated during the SARS-CoV-2 pandemics, their versatility and unique protocols allowed for fast adaptation to novel immunogens. These advantages can benefit the HIV vaccine field that is in dire need of delivery platforms that can be rapidly adapted to a highly mutating virus, while being highly immunogenic. Hence, combining the most relevant HIV immunogens as soluble proteins or those displayed on multivalent platforms with DNA and mRNA systems can pave the way towards the development of HIV vaccines. View this paper
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Vaccines - ISSN 2076-393X