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Vaccines, Volume 12, Issue 9

September 2024 - 135 articles

Cover Story: The Varicella Zoster Virus (VZV) is a common pathogen, but the consequences of VZV infection are anything but negligible, particularly in subjects affected by primary or secondary immune deficiencies. Healthcare-associated transmission of VZV by susceptible healthcare workers (HCWs) represents a threat to the patients’ safety, which should be avoided by ensuring that all HCWs have evidence of immunity to VZV and delivering the VZV vaccine when needed. In this study, we gathered the available evidence on the VZV immunization status of HCWs. The pooled sample included a total of 71,720 HCWs, documenting a non-negligible seronegative status for VZV of 5.72% (95% confidence interval [95% CI] 4.59 to 7.10), with a higher risk for younger individuals compared to the older ones, stressing the importance of systematically testing newly hired workers for VZV. View this paper
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Articles (135)

  • Article
  • Open Access
3 Citations
2,980 Views
16 Pages

Varicella-Zoster Disease of the Central Nervous System in Immunocompetent Children: Case Series and a Scoping Review

  • Dawid Lewandowski,
  • Kacper Toczylowski,
  • Malgorzata Kowalska,
  • Milena Krasnodębska,
  • Iryna Krupienko,
  • Karolina Nartowicz,
  • Magdalena Sulik and
  • Artur Sulik

23 September 2024

Background: Varicella-Zoster Virus (VZV) is characterized by its ability to enter a dormant state within the body. When the wild or vaccine virus reactivates, it can lead to herpes zoster (HZ), which infrequently manifests as a neuroinfection. Object...

  • Article
  • Open Access
1,645 Views
15 Pages

Case Study: Contribution of Extended Sequencing and Phylogeographic Analysis in the Investigation of Measles Outbreaks in Tunisia in 2019

  • Anissa Chouikha,
  • Marwa Arbi,
  • Oussama Souiai,
  • Henda Touzi,
  • Zina Meddeb,
  • Essia Ben Farhat,
  • Mahrez Yahyaoui,
  • Amel Ben Said,
  • Chokri Hamouda and
  • Henda Triki

23 September 2024

Despite the availability of an effective vaccine for several decades, the measles virus continues to spread worldwide. From 2018 to 2019, several countries experienced large measles outbreaks with genotype B3, including Tunisia. We analyzed 66 sample...

  • Article
  • Open Access
3 Citations
2,031 Views
15 Pages

Exploring Important Attributes, the Potential Use Cases and Feasibility of Introduction of Measles and Rubella Microarray Patches (MR-MAPs): Insights from Nine Countries

  • Mateusz Hasso-Agopsowicz,
  • Dijana Spasenoska,
  • Maarten Paul Maria Jansen,
  • Balcha Girma Masresha,
  • Desiree Pastor,
  • Abay Hagos Gebrekidan,
  • Olivi Silalahi,
  • Janice Woolford,
  • Annet Kisakye and
  • Anna-Lea Kahn
  • + 1 author

23 September 2024

Background: Microarray patches (MAPs) are innovative, needle-free vaccine delivery systems, suitable for administration by minimally trained health care workers or trained community health workers. Their introduction may transform immunization progra...

  • Article
  • Open Access
2 Citations
2,499 Views
17 Pages

Estimates of Potential Demand for Measles and Rubella Microarray Patches

  • Lidia K. Kayembe,
  • Leah S. Fischer,
  • Bishwa B. Adhikari,
  • Jennifer K. Knapp,
  • Emily B. Khan,
  • Bradford R. Greening,
  • Mark Papania and
  • Martin I. Meltzer

23 September 2024

Global measles vaccine coverage has stagnated at approximately 85% for over a decade. By simplifying vaccine logistics and administration, the measles and rubella microarray patch (MR-MAP) may improve coverage. Clinical trials have demonstrated simil...

  • Article
  • Open Access
1 Citations
1,750 Views
13 Pages

22 September 2024

Objectives: This study examines the recommendation behaviors and influencing factors for the 13-valent Pneumococcal Conjugate Vaccine (PCV13) among 3579 Chinese healthcare workers (HCWs), including 1775 pediatric care providers (P...

  • Article
  • Open Access
2 Citations
3,455 Views
26 Pages

Comprehensive Spatial-Temporal and Risk Factor Insights for Optimizing Livestock Anthrax Vaccination Strategies in Karnataka, India

  • Jayashree Anandakumar,
  • Kuralayanapalya Puttahonnappa Suresh,
  • Archana Veeranagouda Patil,
  • Chethan A. Jagadeesh,
  • Sushma Bylaiah,
  • Sharanagouda S. Patil and
  • Divakar Hemadri

22 September 2024

Anthrax, a zoonotic disease affecting both livestock and humans globally, is caused by Bacillus anthracis. The objectives of this study were the following: (1) to identify environmental risk factors for anthrax and use this information to develop an...

  • Article
  • Open Access
1 Citations
1,807 Views
13 Pages

21 September 2024

Background: In many countries, an increase in influenza and pneumococcal vaccination rates was observed during the COVID-19 pandemic. We examined how attitude, risk perception and knowledge towards influenza and pneumococcal vaccines of at-risk patie...

  • Article
  • Open Access
1,766 Views
13 Pages

Antibody Persistence and Risk of COVID-19 Infection: Insights from Modeling

  • Laurent Coudeville,
  • Eleine Konate,
  • Tabassome Simon,
  • Xavier de Lamballerie,
  • Scott Patterson,
  • Clotilde El Guerche-Séblain and
  • Odile Launay

21 September 2024

Background: In this post hoc exploratory study of the APHP-COVIBOOST trial (NCT05124171), we used statistical modeling to describe the evolution of neutralizing antibody (nAb) titers over time, asses its impact on SARS-CoV-2 infection, and explore po...

  • Review
  • Open Access
1 Citations
3,227 Views
19 Pages

20 September 2024

Background: Pseudorabies virus (PRV) is a highly infectious pathogen that affects a wide range of mammals and imposes a significant economic burden on the global pig industry. The viral envelope of PRV contains several glycoproteins, including glycop...

  • Article
  • Open Access
2 Citations
2,766 Views
19 Pages

Vaccine Potency and Structure of Yeast-Produced Polio Type 2 Stabilized Virus-like Particles

  • Qin Hong,
  • Shuxia Wang,
  • Xiaoli Wang,
  • Wenyu Han,
  • Tian Chen,
  • Yan Liu,
  • Fei Cheng,
  • Song Qin,
  • Shengtao Zhao and
  • Qingwei Liu
  • + 2 authors

20 September 2024

Poliovirus (PV) is on the brink of eradication due to global vaccination programs utilizing live-attenuated oral and inactivated polio vaccines. Recombinant PV virus-like particles (VLPs) are emerging as a safe next-generation vaccine candidate for t...

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Vaccines - ISSN 2076-393XCreative Common CC BY license