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Medical Sciences, Volume 13, Issue 4

December 2025 - 28 articles

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Articles (28)

  • Article
  • Open Access

Incidence and Survival of IDH-Wildtype Glioblastoma and IDH-Mutant Astrocytoma by Treatment and Sex: A Regional Study in Spain (2011–2021)

  • J. A. Encarnación,
  • C. Manso,
  • M. Royo-Villanova,
  • P. Ruiz,
  • M. I. De la Fuente,
  • E. Cárdenas,
  • S. Ros and
  • J. L. Alonso-Romero
Med. Sci.2025, 13(4), 233;https://doi.org/10.3390/medsci13040233 
(registering DOI)

14 October 2025

Background: The incidence and prognosis of high-grade gliomas differ according to histopathological and molecular features. The WHO 2021 CNS classification emphasized IDH status, but historical cohorts often lacked systematic molecular profiling. Met...

  • Article
  • Open Access

Evaluation of Platelet Indices and Reticulated Platelets Using the ADVIA 2120 Analyzer in Patients with Acute Infection or Acute Coronary Syndrome, at Onset

  • Vincenzo Brescia,
  • Antonella Mileti,
  • Roberto Lovero,
  • Lucia Varraso,
  • Francesco Pignataro,
  • Francesca Di Serio,
  • Angela Pia Cazzolla,
  • Luigi Santacroce,
  • Maria Eleonora Bizzoca and
  • Vito Crincoli
  • + 1 author

14 October 2025

Background: The aim of this study was to evaluate the changes in platelet indices (PLT) provided by the ADVIA 2120 hematology analyzer (Siemens Hematology System) in the early stages of onset of infections and acute coronary syndromes (ACSs). Methods...

  • Review
  • Open Access

Prospects of AI-Powered Bowel Sound Analytics for Diagnosis, Characterization, and Treatment Management of Inflammatory Bowel Disease

  • Divyanshi Sood,
  • Zenab Muhammad Riaz,
  • Jahnavi Mikkilineni,
  • Narendra Nath Ravi,
  • Vineeta Chidipothu,
  • Gayathri Yerrapragada,
  • Poonguzhali Elangovan,
  • Mohammed Naveed Shariff,
  • Thangeswaran Natarajan and
  • Jayarajasekaran Janarthanan
  • + 4 authors

13 October 2025

Background: This narrative review examines the role of artificial intelligence (AI) in bowel sound analysis for the diagnosis and management of inflammatory bowel disease (IBD). Inflammatory bowel disease (IBD), encompassing Crohn’s disease and...

  • Article
  • Open Access

From Gamma Rays to Green Light: Comparative Efficacy of Indocyanine Green and Technetium-99m in Sentinel Lymph Node Biopsy for Breast Cancer

  • Vlad Alexandru Gâta,
  • Radu Alexandru Ilieș,
  • Nicoleta Zenovia Antone,
  • Roxana Pintican,
  • Codruț Cosmin Nistor-Ciurba,
  • Ștefan Țîțu,
  • Alex Victor Orădan,
  • Maximilian Vlad Muntean,
  • Gheorghe Gerald Filip and
  • Alexandru Irimie
  • + 1 author

13 October 2025

Background/Objectives: Sentinel lymph node biopsy (SLNB) is currently the standard approach for axillary staging in breast cancer. Conventional techniques are radioisotope-based (Technetium-99m, Tc99m) and remain widely used, but novel tracers like I...

  • Article
  • Open Access
81 Views
12 Pages

Evaluation of Carcinoembryonic Antigen as a Prognostic Marker for Colorectal Cancer Relapse: Insights from Postoperative Surveillance

  • Stefan Titu,
  • Radu Alexandru Ilies,
  • Teodora Mocan,
  • Alexandru Irimie,
  • Vlad Alexandru Gata and
  • Cosmin Ioan Lisencu

12 October 2025

Background/Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality worldwide. This study evaluates the predictive value of Carcinoembryonic Antigen (CEA) in identifying CRC recurrence following surgical resect...

  • Communication
  • Open Access
104 Views
12 Pages

Is Night Shift Work Associated with Ovarian Cancer? A Systematic Review and Meta-Analysis

  • Ahmed Arafa,
  • Mazin Alhussein,
  • Amin Alayyan,
  • Haytham A. Sheerah,
  • Mona S. Ibrahim,
  • Abeer S. Alasmari,
  • Sarah A. Barzanji,
  • Samah A. Bukhari,
  • Alhanouf K. Althaydi and
  • Ehab Elkady
  • + 2 authors

12 October 2025

Background: Night shift work has been classified as a probable carcinogen due to its disruption of circadian rhythms. However, whether night shift work can increase the risk of ovarian cancer remains unclear. Herein, we investigated this association...

  • Article
  • Open Access
106 Views
12 Pages

Limited Prognostic Value of Psoas Muscle Indices in Patients Undergoing Revascularization for Chronic Limb-Threatening Ischemia

  • Joanna Halman,
  • Jakub Dybcio,
  • Kamil Myszczyński,
  • Nina Kimilu,
  • Agnieszka Blacha,
  • Grzegorz Owedyk,
  • Jacek Wojciechowski and
  • Mariusz Siemiński

12 October 2025

Background: Sarcopenia is linked with high rates of adverse surgical outcomes, and computed tomography angiography (CTA)-based psoas measurements are used as imaging sarcopenia surrogates. Their prognostic value in patients with chronic limb-threaten...

  • Article
  • Open Access
223 Views
24 Pages

A Compartmental Mathematical Model to Assess the Impact of Vaccination, Isolation, and Key Epidemiological Parameters on Mpox Control

  • Pedro Pesantes-Grados,
  • Nahía Escalante-Ccoyllo,
  • Olegario Marín-Machuca,
  • Abel Walter Zambrano-Cabanillas,
  • Homero Ango-Aguilar,
  • Obert Marín-Sánchez and
  • Ruy D. Chacón

10 October 2025

Background: Monkeypox (Mpox) is a re-emerging zoonotic disease caused by the monkeypox virus (MPXV). Transmission occurs primarily through direct contact with lesions or contaminated materials, with sexual transmission playing a significant role in r...

  • Article
  • Open Access
245 Views
16 Pages

Understanding Patient Decision-Making in Breast Cancer Surgery: Risk Perception, Communication, and Psychosocial Influences

  • Eman Sbaity,
  • Tasnim Diab,
  • Jana Haroun,
  • Nagham Ramadan,
  • Ghina Khalil,
  • Nathalie Chamseddine,
  • Rawan Diab,
  • Hadi Mansour,
  • Mohyeddine El Sayed and
  • Maya Charafeddine
  • + 2 authors

9 October 2025

Background: Despite evidence discouraging contralateral prophylactic mastectomy (CPM) in average-risk patients, its use is increasing globally. While well-studied in Western settings, little is known about the factors influencing CPM decisions in the...

  • Article
  • Open Access
287 Views
16 Pages

Clinical, Endoscopic and Histologic Differences in Gastric Mucosa Between Younger and Older Adults: An Observational Study on the Aging Stomach

  • Francisco Vara-Luiz,
  • Ivo Mendes,
  • Carolina Palma,
  • Paulo Mascarenhas,
  • Ana Elisa Teles,
  • Inês Costa Santos,
  • Gonçalo Nunes,
  • Marta Patita,
  • Irina Mocanu and
  • Sara Pires
  • + 5 authors

8 October 2025

Background/Objectives: Age-related changes in the gastric mucosa remain incompletely understood. We aimed to assess and compare clinical, endoscopic and histologic changes in the gastric mucosa associated with aging, and to explore whether gastric ag...

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