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Microorganisms, Volume 9, Issue 8

August 2021 - 248 articles

Cover Story: We speculated whether SARS-CoV-2 interference in the hematopoietic progenitor differentiation process could be the cause of thrombotic events in either COVID-19 patients or vaccinated individuals. The premises are: (i) the subversive activity perpetrated by the SARS-CoV-2 virus inside targeted CD34+ hemopoietic stem cells at the very beginning of the differentiation phase towards the myeloid lineage red cells and platelets. (ii) The presence of different single nucleotide polymorphisms (SNPs) in the individual’s genetic make-up that involve genes regulating immune system responses and genes controlling the coagulation mechanism. View this paper.
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Articles (248)

  • Article
  • Open Access
7 Citations
4,227 Views
18 Pages

MDR and Pre-XDR Clinical Mycobacterium tuberculosis Beijing Strains: Assessment of Virulence and Host Cytokine Response in Mice Infectious Model

  • Mikhail V. Fursov,
  • Egor A. Shitikov,
  • Denis A. Lagutkin,
  • Anastasiia D. Fursova,
  • Elena A. Ganina,
  • Tatiana I. Kombarova,
  • Natalia S. Grishenko,
  • Tatiana I. Rudnitskaya,
  • Dmitry A. Bespiatykh and
  • Nadezhda V. Kolupaeva
  • + 9 authors

Mycobacterium tuberculosis Beijing genotype associated with drug resistance is a growing public health problem worldwide. The aim of this study was the assessment of virulence for C57BL/6 mice after infection by clinical M. tuberculosis strains 267/4...

  • Article
  • Open Access
4 Citations
2,981 Views
10 Pages

Intestinal Colonization with Tropheryma whipplei—Clinical and Immunological Implications for HIV Positive Adults in Ghana

  • Kirsten Alexandra Eberhardt,
  • Fred Stephen Sarfo,
  • Eva-Maria Klupp,
  • Albert Dompreh,
  • Veronica Di Cristanziano,
  • Edmund Osei Kuffour,
  • Richard Boateng,
  • Betty Norman,
  • Richard Odame Phillips and
  • Martin Aepfelbacher
  • + 1 author

Background: Recent studies demonstrated higher prevalence rates of Tropheryma whipplei (T. whipplei) in HIV positive than in HIV negative subjects. However, associations with the immune status in HIV positive participants were conflicting. Methods: F...

  • Article
  • Open Access
17 Citations
5,649 Views
20 Pages

From Water into Sediment—Tracing Freshwater Cyanobacteria via DNA Analyses

  • Ebuka Canisius Nwosu,
  • Patricia Roeser,
  • Sizhong Yang,
  • Lars Ganzert,
  • Olaf Dellwig,
  • Sylvia Pinkerneil,
  • Achim Brauer,
  • Elke Dittmann,
  • Dirk Wagner and
  • Susanne Liebner

Sedimentary ancient DNA-based studies have been used to probe centuries of climate and environmental changes and how they affected cyanobacterial assemblages in temperate lakes. Due to cyanobacteria containing potential bloom-forming and toxin-produc...

  • Article
  • Open Access
11 Citations
3,078 Views
11 Pages

Antimicrobial Peptide L18R Displays a Modulating Action against Inter-Kingdom Biofilms in the Lubbock Chronic Wound Biofilm Model

  • Paola Di Fermo,
  • Tecla Ciociola,
  • Silvia Di Lodovico,
  • Simonetta D’Ercole,
  • Morena Petrini,
  • Laura Giovati,
  • Stefania Conti,
  • Mara Di Giulio and
  • Luigina Cellini

Chronic wound infections represent an important health problem due to the reduced response to antimicrobial treatment of the pathogens organized in structured biofilms. This study investigated the effects of the previously described antifungal peptid...

  • Article
  • Open Access
4 Citations
3,294 Views
17 Pages

Bioinformatics Investigations of Universal Stress Proteins from Mercury-Methylating Desulfovibrionaceae

  • Raphael D. Isokpehi,
  • Dominique S. McInnis,
  • Antoinette M. Destefano,
  • Gabrielle S. Johnson,
  • Akimio D. Walker,
  • Yessenia A. Hall,
  • Baraka W. Mapp,
  • Matilda O. Johnson and
  • Shaneka S. Simmons

The presence of methylmercury in aquatic environments and marine food sources is of global concern. The chemical reaction for the addition of a methyl group to inorganic mercury occurs in diverse bacterial taxonomic groups including the Gram-negative...

  • Article
  • Open Access
2 Citations
2,595 Views
11 Pages

Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System

  • Silvia Otero-Rodriguez,
  • Oscar Moreno-Pérez,
  • Jose Manuel Ramos,
  • Mar García,
  • Vicente Boix,
  • Sergio Reus,
  • Diego Torrus,
  • Pablo Chico-Sánchez,
  • José Sánchez-Payá and
  • Fernando Aldana-Macias
  • + 4 authors

Exploring differences in clinical outcomes based on race and origin among patients hospitalized for COVID-19 is a controversial issue. The ALC COVID-19 Registry includes all confirmed COVID-19 patients admitted to hospital from 3 March 2020 to 17 Dec...

  • Review
  • Open Access
48 Citations
5,359 Views
14 Pages

Introduction. It is known that bacterial infections represent a common complication during viral respiratory tract infections such as influenza, with a concomitant increase in morbidity and mortality. Nevertheless, the prevalence of bacterial co-infe...

  • Article
  • Open Access
8 Citations
3,527 Views
14 Pages

The elderly and adults with medical risk conditions remain at high risk of invasive pneumococcal disease (IPD), highlighting the importance of adequate preventive efforts. In an observational population-based study in Norway (pop ≥ 5 years, 2009–2017...

  • Article
  • Open Access
15 Citations
8,069 Views
13 Pages

Comparative Pan-Genome Analysis of Oral Veillonella Species

  • Izumi Mashima,
  • Yu-Chieh Liao,
  • Chieh-Hua Lin,
  • Futoshi Nakazawa,
  • Elaine M. Haase,
  • Yusuke Kiyoura and
  • Frank A. Scannapieco

The genus Veillonella is a common and abundant member of the oral microbiome. It includes eight species, V. atypica, V. denticariosi, V. dispar, V. infantium, V. nakazawae, V. parvula, V. rogosae and V. tobetusensis. They possess important metabolic...

  • Article
  • Open Access
19 Citations
4,486 Views
18 Pages

Hybridized Zoonotic Schistosoma Infections Result in Hybridized Morbidity Profiles: A Clinical Morbidity Study amongst Co-Infected Human Populations of Senegal

  • Cheikh B. Fall,
  • Sébastien Lambert,
  • Elsa Léger,
  • Lucy Yasenev,
  • Amadou Djirmay Garba,
  • Samba D. Diop,
  • Anna Borlase,
  • Stefano Catalano,
  • Babacar Faye and
  • Martin Walker
  • + 2 authors

Hybridization of infectious agents is a major emerging public and veterinary health concern at the interface of evolution, epidemiology, and control. Whilst evidence of the extent of hybridization amongst parasites is increasing, their impact on morb...

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Microorganisms - ISSN 2076-2607