You are currently on the new version of our website. Access the old version .

Pathogens, Volume 14, Issue 2

2025 February - 101 articles

Cover Story: Leishmaniasis is a devastating yet neglected tropical disease which affects millions of people worldwide. Polyamine biosynthesis has emerged as a promising therapeutic target in Leishmania, yet many of the key functions of polyamines in these parasites remain unclear. In this study, we examined the essential role of putrescine in Leishmania survival. Our findings show that depriving Leishmania donovani of putrescine abruptly halts parasite growth, disrupts reductive metabolism, alters mitochondrial function, and triggers an apoptotic-like cell death, making ODC a prime target. These findings open new avenues for treating leishmaniasis by disrupting polyamine metabolism. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (101)

  • Article
  • Open Access
1,290 Views
11 Pages

First Molecular Detection of Rickettsia conorii and Rickettsia helvetica in Ticks from Dogs in Luxembourg

  • Guilherme Moreira,
  • Rafaela S. S. Moreira,
  • Floriane André das Neves,
  • Vanessa Swiontek,
  • Patrícia F. Barradas,
  • Sara Gomes-Gonçalves and
  • João R. Mesquita

19 February 2025

Vector-borne diseases, particularly those caused by Rickettsia species, pose a significant public health threat in Europe. Despite extensive research on tick-borne pathogens in various European countries, Luxembourg has yet not been studied for Ricke...

  • Article
  • Open Access
1 Citations
2,822 Views
13 Pages

Contrasting Effect of Curcumin on Hepatitis B Virus Replication According to the Hepatoma Cell Line

  • María Mercedes Elizalde,
  • Pedro Fuentes,
  • Diego Chiappetta and
  • Diego Martín Flichman

19 February 2025

In recent decades, considerable advances have been achieved in the treatment of chronic hepatitis B. However, the currently available drugs have shortcomings. In this context, several natural compounds have been proposed as potential agents to improv...

  • Article
  • Open Access
1 Citations
1,836 Views
11 Pages

Fatal Toxoplasmosis in Red Kangaroos (Macropus rufus) in East China

  • Haiyan Gong,
  • Quan Wang,
  • Yinghong Jin,
  • Suoping Qiu,
  • Zhaoguo Chen,
  • Xiangan Han,
  • Zongyan Chen and
  • Wei Jiang

19 February 2025

Background: As a ubiquitous apicomplexan parasite, Toxoplasma gondii causes huge economic losses and poses a great threat to the health of animals, including humans, worldwide. In some kangaroo species, T. gondii can be fatal. To date, little informa...

  • Article
  • Open Access
4 Citations
2,570 Views
26 Pages

Characterization of Fungal Pathogens Causing Blueberry Fruit Rot Disease in China

  • Yueyan Zhou,
  • Wei Zhang,
  • Linna Wu,
  • Pengzhao Chen,
  • Xinghong Li,
  • Guangqin Wen,
  • Khanobporn Tangtrakulwanich,
  • Kandawatte Wedaralalage Thilini Chethana,
  • Fatimah Al-Otibi and
  • Jiye Yan
  • + 1 author

18 February 2025

Blueberry has been a burgeoning fruit in China in recent years, but its perishable nature places a constant strain on industrial development. To determine the pathogens infecting blueberry fruits, diseased samples were collected from Guizhou and Fuji...

  • Review
  • Open Access
3 Citations
4,261 Views
25 Pages

18 February 2025

Canine adenovirus type 1 (CAdV-1) and type 2 (CAdV-2) are well known pathogens of domestic dogs but are little investigated in wild animals. The few available studies about CAdV-1 in wild animals show that it circulates in various species and that tr...

  • Article
  • Open Access
5 Citations
1,827 Views
12 Pages

Old Bug—New Challenges After COVID-19 Pandemic: Severe Invasive Streptococcus pyogenes Infections in Adults—A Single-Center Experience in Poland

  • Patrycja Leśnik,
  • Jarosław Janc,
  • Martyna Biała,
  • Marzenna Bartoszewicz,
  • Lidia Łysenko and
  • Natalia Słabisz

17 February 2025

Since the beginning of December 2022, an unusually high number of cases and deaths of Group A Streptococcus (GAS) infections has been reported in many European countries. GAS infection frequently causes mild diseases such as pharyngitis, tonsillitis,...

  • Article
  • Open Access
1 Citations
1,992 Views
19 Pages

16 February 2025

This study aimed to evaluate the burden of HPV-related hospitalization and mortality in Greece, with a focus on invasive cervical cancer and lip, oral cavity, and pharyngeal (LOCP) cancers. A retrospective query using data from the Greek Statistical...

  • Article
  • Open Access
3 Citations
1,522 Views
9 Pages

Evaluation of IgM, IgA, and IgG Antibody Responses Against PCV3 and PCV2 in Tissues of Aborted Fetuses from Late-Term Co-Infected Sows

  • Jesús Hernández,
  • Alexandra Henao-Díaz,
  • Mónica Reséndiz-Sandoval,
  • Joana Ramírez-Morán,
  • Angel Cota-Valdez,
  • Verónica Mata-Haro and
  • Luis G. Giménez-Lirola

16 February 2025

Porcine circovirus type 2 (PCV2) is a ubiquitous pathogen, and co-infections with the emerging PCV3 are increasingly reported. Both PCV2 and PCV3 have been implicated in reproductive failure, yet the diagnostic criteria for PCV3 remain under developm...

  • Review
  • Open Access
8 Citations
7,792 Views
23 Pages

15 February 2025

The Bacillus Calmette–Guérin (BCG) vaccine, best known for its role in preventing tuberculosis, has recently garnered attention for its broader immunomodulatory effects. By inducing trained immunity, BCG reprograms innate immune cells, e...

  • Article
  • Open Access
2 Citations
1,837 Views
15 Pages

Sex, Age, and Previous Herpes Zoster Infection Role on Adverse Events Following Immunization with Adjuvanted Recombinant Vaccine

  • Maria Costantino,
  • Valentina Giudice,
  • Giuseppina Moccia,
  • Monica Ragozzino,
  • Salvatore Calabrese,
  • Francesco Caiazzo,
  • Massimo Beatrice,
  • Walter Longanella,
  • Simona Caruccio and
  • Francesco De Caro
  • + 7 authors

15 February 2025

Adverse events following immunizations (AEFIs) with recombinant zoster vaccine (RZV) are underexplored in fragile populations. This study aims to assess incidence, duration, and characteristics of AEFIs, focusing on the impact of sex, age, and prior...

of 11

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Pathogens - ISSN 2076-0817