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Pathogens, Volume 12, Issue 8

August 2023 - 97 articles

Cover Story: Tick-borne pathogens (TBPs) pose a significant problem globally, particularly in tropical and subtropical regions, impacting both livestock industries and animal health. In Cuba, key pathogens affecting cattle include Babesia bovis, Babesia bigemina, and Anaplasma marginale. These pathogens are primarily transmitted by the Rhipicephalus microplus tick. Diagnosing these infections is challenging, due to low parasitemia levels during persistent infections and cross-reactivity. Molecular techniques such as PCR variants are essential for diagnosis. A drawback of PCR-based methods is their inability to simultaneously detect pathogens. However, high-throughput microfluidic methods enable for the concurrent detection of various pathogens. This study aims to investigate TBPs in cattle and ticks at four sampling points using real-time microfluidic PCR. View this paper
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Articles (97)

  • Brief Report
  • Open Access
6 Citations
1,909 Views
7 Pages
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Prevalence of Infectious Hypodermal and Hematopoietic Necrosis Virus (IHHNV) in Farmed Procambarus clarkii of the Middle and Lower Reaches of the Yangtze River in China

  • Feng Xu,
  • Yongwei Wei,
  • Jianfei Lu and
  • Jiong Chen
Pathogens2023, 12(8), 1038;https://doi.org/10.3390/pathogens12081038

14 August 2023

Procambarus clarkii is an important economic aquaculture species worldwide. Infectious hypodermal and hematopoietic necrosis virus (IHHNV) infects numerous crustacean hosts, including P. clarkii. However, there have been few reports on the prevalence...

Full Article
  • Perspective
  • Open Access
3 Citations
7,053 Views
9 Pages
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Epilepsy Due to Solitary Calcified Cysticercus Granuloma

  • Jagarlapudi M. K. Murthy
Pathogens2023, 12(8), 1037;https://doi.org/10.3390/pathogens12081037

14 August 2023

The calcified stage of the neurocysticercosis (NCC) is the common cause of acquired epilepsy in low and middle income countries in people aged > 20 years. Approximately 30% of adult onset seizures and epilepsy are attributable to NCC. In India and...

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  • Article
  • Open Access
17 Citations
8,296 Views
23 Pages
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Brucella ceti Infection in Striped Dolphins from Italian Seas: Associated Lesions and Epidemiological Data

  • Carla Grattarola,
  • Antonio Petrella,
  • Giuseppe Lucifora,
  • Gabriella Di Francesco,
  • Fabio Di Nocera,
  • Antonio Pintore,
  • Cristiano Cocumelli,
  • Giuliana Terracciano,
  • Antonio Battisti and
  • Ludovica Di Renzo
  • + 17 authors
Pathogens2023, 12(8), 1034;https://doi.org/10.3390/pathogens12081034

13 August 2023

Brucella ceti infections have been increasingly reported in cetaceans. In this study, we analyzed all cases of B. ceti infection detected in striped dolphins stranded along the Italian coastline between 2012 and 2021 (N = 24). We focused on the patho...

Full Article
  • Review
  • Open Access
16 Citations
4,905 Views
17 Pages
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Nanotechnology-Based Strategies to Combat Multidrug-Resistant Candida auris Infections

  • Helal F. Hetta,
  • Yasmin N. Ramadan,
  • Israa M. S. Al-Kadmy,
  • Noura H. Abd Ellah,
  • Lama Shbibe and
  • Basem Battah
Pathogens2023, 12(8), 1033;https://doi.org/10.3390/pathogens12081033

13 August 2023

An emerging multidrug-resistant pathogenic yeast called Candida auris has a high potential to spread quickly among hospitalized patients and immunodeficient patients causing nosocomial outbreaks. It has the potential to cause pandemic outbreaks in ab...

Full Article
  • Systematic Review
  • Open Access
10 Citations
3,224 Views
19 Pages
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Variability of High-Risk Human Papillomavirus and Associated Factors among Women in Sub-Saharan Africa: A Systematic Review and Meta-Analysis

  • Michel Carlos Tommo Tchouaket,
  • Aude Christelle Ka’e,
  • Ezechiel Ngoufack Jagni Semengue,
  • Samuel Martin Sosso,
  • Rachel Kamgaing Simo,
  • Bouba Yagai,
  • Alex Durand Nka,
  • Collins Ambe Chenwi,
  • Aissatou Abba and
  • Nadine Fainguem
  • + 3 authors
Pathogens2023, 12(8), 1032;https://doi.org/10.3390/pathogens12081032

11 August 2023

Background: Sub-Saharan Africa (SSA) carries the highest burden of high-risk human papillomavirus (HR-HPV) in the world, driven by, and together with, HIV infection. This systematic review aimed to identify HR-HPV genotypes and their associated facto...

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  • Article
  • Open Access
5 Citations
2,321 Views
13 Pages
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Experimental Infection of Pigs with a Traditional or a Variant Porcine Respiratory Coronavirus (PRCV) Strain and Impact on Subsequent Influenza A Infection

  • Gaurav Rawal,
  • Jianqiang Zhang,
  • Patrick G. Halbur,
  • Phillip C. Gauger,
  • Chong Wang and
  • Tanja Opriessnig
Pathogens2023, 12(8), 1031;https://doi.org/10.3390/pathogens12081031

11 August 2023

Porcine respiratory coronavirus (PRCV) pathogenicity in pigs has been characterized using traditional PRCV isolates; however, information is lacking on pathogenicity of currently circulating PRCV isolates. Recently, a contemporary US PRCV variant was...

Full Article
  • Review
  • Open Access
1,805 Views
13 Pages
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Nuclear Morphofunctional Organization and Epigenetic Characteristics in Somatic Cells of T. infestans (Klug, 1834)

  • Maria Luiza S. Mello
Pathogens2023, 12(8), 1030;https://doi.org/10.3390/pathogens12081030

11 August 2023

Triatoma infestans (Klug) is an insect recognized as not only an important vector of South American trypanosomiasis (Chagas disease) but also a model of specific cellular morphofunctional organization and epigenetic characteristics. The purpose of th...

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  • Brief Report
  • Open Access
4 Citations
2,248 Views
8 Pages
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Anaplasma phagocytophilum Ecotype Analysis in Cattle from Great Britain

  • Ternenge Thaddaeus Apaa,
  • Harriet McFadzean,
  • Sara Gandy,
  • Kayleigh Hansford,
  • Jolyon Medlock and
  • Nicholas Johnson
Pathogens2023, 12(8), 1029;https://doi.org/10.3390/pathogens12081029

10 August 2023

Anaplasma phagocytophilum (A. phagocytophilum) is the aetiological agent of tick-borne fever in cattle and sheep, and granulocytic anaplasmosis in human and dogs. Livestock, companion animal and human infections with A. phagocytophilum have been repo...

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