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Pathogens, Volume 12, Issue 3

March 2023 - 150 articles

Cover Story: Protein synthesis is a central process in all cells, and its regulation plays a key role in bacteria–host interactions. One of the important aspects of protein synthesis is limiting errors and maintaining translational fidelity. In this review, we summarize recent findings on how translational fidelity in bacteria is altered by genetic and environmental cues and, in turn, affects stress adaptations and host interactions. We also point out some future directions to understand the role of translational fidelity in the pathogenesis of various bacterial species, an emerging area in studying bacteria–pathogen interactions. View this paper
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Articles (150)

  • Article
  • Open Access
2 Citations
3,666 Views
9 Pages

Household Surveillance for Norovirus Gastroenteritis in a Nicaraguan Birth Cohort: A Nested Case—Control Analysis of Norovirus Risk Factors

  • Nadja Alexandra Vielot,
  • Omar Zepeda,
  • Yaoska Reyes,
  • Fredman González,
  • Jan Vinjé,
  • Sylvia Becker-Dreps and
  • Filemón Bucardo

Norovirus causes a large proportion of pediatric acute gastroenteritis (AGE) worldwide, and no vaccines are currently available. To inform public health measures against norovirus gastroenteritis, we assessed risk factors in a case–control stud...

  • Article
  • Open Access
5 Citations
4,534 Views
7 Pages

Cases of rocky mountain spotted fever (RMSF) are increasingly reported every year in Long Island, New York. In clinical practice, an uncommonly high number of referrals with a positive RMSF IgG test result have been seen in our tick-borne disease cli...

  • Article
  • Open Access
6 Citations
2,425 Views
8 Pages

Campylobacter spp. Prevalence in Santiago, Chile: A Study Based on Molecular Detection in Clinical Stool Samples from 2014 to 2019

  • Lorena Porte,
  • Caricia Pérez,
  • Mario Barbé,
  • Carmen Varela,
  • Valeska Vollrath,
  • Paulette Legarraga and
  • Thomas Weitzel

Campylobacter spp. is an emerging cause of infectious diarrhea worldwide. In South American countries such as Chile, its prevalence is underestimated due to inadequate detection methods. Gastrointestinal multiplex PCR panels (GMP) permit rapid and se...

  • Article
  • Open Access
5 Citations
3,753 Views
21 Pages

Complete Genome Sequence and Analysis of a ST573 Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus SauR3 Clinical Isolate from Terengganu, Malaysia

  • Esra’a I. Al-Trad,
  • Ainal Mardziah Che Hamzah,
  • Suat Moi Puah,
  • Kek Heng Chua,
  • Muhamad Zarul Hanifah,
  • Qasim Ayub,
  • Prasit Palittapongarnpim,
  • Stephen M. Kwong,
  • Ching Hoong Chew and
  • Chew Chieng Yeo

Methicillin-resistant Staphylococcus aureus (MRSA) is a World Health Organization-listed priority pathogen. Scarce genomic data are available for MRSA isolates from Malaysia. Here, we present the complete genome sequence of a multidrug-resistant MRSA...

  • Article
  • Open Access
17 Citations
4,870 Views
19 Pages

Synergistic Inhibitory Effect of Honey and Lactobacillus plantarum on Pathogenic Bacteria and Their Promotion of Healing in Infected Wounds

  • Mei Li,
  • Hong Xiao,
  • Yongmei Su,
  • Danlin Cheng,
  • Yan Jia,
  • Yingli Li,
  • Qi Yin,
  • Jieying Gao,
  • Yong Tang and
  • Qunhua Bai

Prevention and control of infections have become a formidable challenge due to the increasing resistance of pathogens to antibiotics. Probiotics have been discovered to have positive effects on the host, and it is well-known that some Lactobacilli ar...

  • Review
  • Open Access
7 Citations
3,388 Views
12 Pages

The Global Expansion of LTBI Screening and Treatment Programs: Exploring Gaps in the Supporting Economic Evidence

  • Nokwanda Thandeka Kota,
  • Suvesh Shrestha,
  • Abdulhameed Kashkary,
  • Pushpita Samina and
  • Alice Zwerling

The global burden of latent TB infection (LTBI) and the progression of LTBI to active TB disease are important drivers of ongoing TB incidence. Addressing LTBI through screening and TB preventive treatment (TPT) is critical in order to end the TB epi...

  • Article
  • Open Access
22 Citations
3,979 Views
19 Pages

Assembly and Analysis of Haemonchus contortus Transcriptome as a Tool for the Knowledge of Ivermectin Resistance Mechanisms

  • David Emanuel Reyes-Guerrero,
  • Verónica Jiménez-Jacinto,
  • Rogelio Alejandro Alonso-Morales,
  • Miguel Ángel Alonso-Díaz,
  • Jocelyn Maza-Lopez,
  • René Camas-Pereyra,
  • Agustín Olmedo-Juárez,
  • Rosa Isabel Higuera-Piedrahita and
  • María Eugenia López-Arellano

Haemonchus contortus (Hc) is an important parasitic nematode of small ruminants. In this study we assembled the transcriptome of Hc as a model to contribute to the knowledge about the profile of the differential gene expression between two Mexican Hc...

  • Article
  • Open Access
4 Citations
3,145 Views
11 Pages

Synergistic Detrimental Effects of Cigarette Smoke, Alcohol, and SARS-CoV-2 in COPD Bronchial Epithelial Cells

  • Abenaya Muralidharan,
  • Christopher D. Bauer,
  • Dawn M. Katafiasz,
  • Heather M. Strah,
  • Aleem Siddique,
  • St Patrick Reid,
  • Kristina L. Bailey and
  • Todd A. Wyatt

Lung conditions such as COPD, as well as risk factors such as alcohol misuse and cigarette smoking, can exacerbate COVID-19 disease severity. Synergistically, these risk factors can have a significant impact on immunity against pathogens. Here, we st...

  • Article
  • Open Access
1 Citations
2,126 Views
14 Pages

Neutralization Sensitivity and Evolution of Virus in a Chronic HIV-1 Clade B Infected Patient with Neutralizing Activity against Membrane-Proximal External Region

  • Wenqi Tang,
  • Zhenzhen Yuan,
  • Zheng Wang,
  • Li Ren,
  • Dan Li,
  • Shuhui Wang,
  • Yanling Hao,
  • Jing Li,
  • Xiuli Shen and
  • Yuhua Ruan
  • + 2 authors

The membrane-proximal external region (MPER) is a promising HIV-1 vaccine target owing to its linear neutralizing epitopes and highly conserved amino acids. Here, we explored the neutralization sensitivity and investigated the MPER sequences in a chr...

  • Article
  • Open Access
5 Citations
2,738 Views
10 Pages

Genetic Determinants of Macrolide and Fluoroquinolone Resistance in Mycoplasma genitalium and Their Prevalence in Moscow, Russia

  • Inna Alexandrovna Edelstein,
  • Alexandr Evgenjevich Guschin,
  • Andrew Vyacheslavovich Romanov,
  • Ekaterina Sergeevna Negasheva and
  • Roman Sergeevich Kozlov

Macrolide (MLR) and fluoroquinolone (FQR) resistance in Mycoplasma genitalium (MG) has recently become a major problem worldwide. The available data on the prevalence of MLR and FQR in MG in Russia are limited. In this study, we aimed to evaluate the...

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Pathogens - ISSN 2076-0817