Campylobacter spp. Prevalence in Santiago, Chile: A Study Based on Molecular Detection in Clinical Stool Samples from 2014 to 2019
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Gastrointestinal Multiplex Panels (GMP)
3.2. Campylobacter Culture
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Year | N | Campylobacter spp. | Salmonella spp. | Shigella spp./EIEC | Yersinia enterocolitica * | |||||
---|---|---|---|---|---|---|---|---|---|---|
Positive (%) | CI95% | Positive (%) | CI95% | Positive (%) | CI95% | n * | Positive (%) | CI95% | ||
2014 | 1440 | 168 (11.7) | 10.1–13.4 | 51 (3.5) | 2.6–4.6 | 10 (0.7) | 0.3–1.3 | 0 | ||
2015 | 2279 | 285 (12.6) | 11.2–13.9 | 103 (4.5) | 3.7–5.5 | 43 (1.8) | 1.3–2.5 | 489 | 5 (1.0) | 0.3–2.4 |
2016 | 3238 | 296 (9.1) | 8.0–10.2 | 125 (3.9) | 3.2–4.6 | 53 (1.6) | 1.2–2.1 | 2319 | 19 (0.8) | 0.5–1.3 |
2017 | 3240 | 277 (8.5) | 7.6–9.6 | 140 (4.3) | 3.6–5.1 | 77 (2.4) | 1.9–3.0 | 2768 | 26 (0.9) | 0.6–1.4 |
2018 | 3124 | 230 (7.4) | 6.5–8.3 | 117 (3.7) | 3.1–4.5 | 76 (2.4) | 1.9–3.0 | 2697 | 29 (1.1) | 0.7–1.5 |
2019 | 3261 | 156 (4.8) | 4.1–5.6 | 117 (3.6) | 3.0–4.3 | 65 (2.0) | 1.5–2.5 | 3001 | 16 (0.5) | 0.3–0.9 |
Total | 16,582 | 1412 (8.5) | 8.1–9.0 | 653 (3.9) | 3.7–4.3 | 324 (1.9) | 1.7–2.2 | 11274 | 95 (0.8) | 0.7–1.0 |
Characteristic | Campylobacter spp. n = 1412 | Salmonella spp. n = 653 | Shigella spp./EIEC n = 323 | Yersinia enterocolitica n = 95 | Total n = 2483 | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
N (%) | CI 95% | N (%) | CI 95% | N (%) | CI 95% | N (%) | CI 95% | N (%) | CI 95% | ||
Sex | Female | 604 (42.8) | 40.2–45.4 | 308 (47.2) | 43.3–51.1 | 163 (50.5) | 44.9–56.0 | 42 (44.2) | 34.0–47.0 | 1117 (45) | 43–47 |
Male | 808 (57.2) | 54.6–59.8 | 345 (52.8) | 48.9–56.7 | 160 (49.5) | 44.0–55.1 | 53 (55.8) | 45.2–66.0 | 1366 (55) | 53–57 | |
Age (years) | Median | 20 | 15 | 28 | 25 | 21 | |||||
IQR | 7–32 | 4–36 | 17–42 | 10–50 | 7–35 | ||||||
Age groups (years) | 0–5 | 312 (22.1) | 201 (30.8) | 33 (10.2) | 17 (17.9) | 563 | |||||
6–18 | 348 (24.6) | 151 (23.1) | 51 (15.8) | 23 (24.2) | 573 | ||||||
19–65 | 674 (47.7) | 267 (41.0) | 221 (68.4) | 44 (46.3) | 1208 | ||||||
>65 | 77 (5.5) | 34 (5.2) | 18 (5.6) | 11 (11.6) | 139 |
Campylobacter Culture | ||||
---|---|---|---|---|
POS | NEG | Total | ||
Filmarray GMP | POS | 313 | 307 | 620 |
NEG | 3 | 3910 | 3913 | |
Total | 316 | 4217 | 4533 |
Reference Standard A * | Reference Standard B ** | |||||
---|---|---|---|---|---|---|
Method | True (+) | False (−) | Sens | True (+) | False (−) | Sens |
Culture | 316 | 0 | 100% | 316 | 307 | 50.7% |
FilmArray GMP | 313 | 3 | 99.1% | 620 | 3 | 99.5% |
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Porte, L.; Pérez, C.; Barbé, M.; Varela, C.; Vollrath, V.; Legarraga, P.; Weitzel, T. Campylobacter spp. Prevalence in Santiago, Chile: A Study Based on Molecular Detection in Clinical Stool Samples from 2014 to 2019. Pathogens 2023, 12, 504. https://doi.org/10.3390/pathogens12030504
Porte L, Pérez C, Barbé M, Varela C, Vollrath V, Legarraga P, Weitzel T. Campylobacter spp. Prevalence in Santiago, Chile: A Study Based on Molecular Detection in Clinical Stool Samples from 2014 to 2019. Pathogens. 2023; 12(3):504. https://doi.org/10.3390/pathogens12030504
Chicago/Turabian StylePorte, Lorena, Caricia Pérez, Mario Barbé, Carmen Varela, Valeska Vollrath, Paulette Legarraga, and Thomas Weitzel. 2023. "Campylobacter spp. Prevalence in Santiago, Chile: A Study Based on Molecular Detection in Clinical Stool Samples from 2014 to 2019" Pathogens 12, no. 3: 504. https://doi.org/10.3390/pathogens12030504