Special Issue "Transfusion-Transmissible Infections and Epidemiological Surveillance"

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: 28 February 2023 | Viewed by 202

Special Issue Editors

Dr. Vincenzo De Angelis
E-Mail Website
Guest Editor
National Blood Centre, Italian National Institute of Health, 00161 Rome, Italy
Interests: immunohaematology; quality systems in laboratory and clinical transfusion; haemostaseology
Special Issues, Collections and Topics in MDPI journals
Dr. Ilaria Pati
E-Mail Website
Guest Editor
National Blood Centre, Italian National Institute of Health, 00161 Rome, Italy
Interests: viruses; transfusion transmitted infections; pathogen reduction; neuroinflammation; neurological infection diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Transfusion-transmissible infectious agents are among the greatest threats to blood safety for transfusion recipients, and are a serious public health problem.

The safety of blood and blood components has dramatically increased over the last several decades thanks to the adoption of strict criteria for blood donor selection and the screening of all blood units for known transfusion-transmissible infections (TTIs), with the combined implementation of highly sensitive antigen/antibody-based assays and nucleic acid testing (NAT), the rational use of blood to avoid unnecessary transfusions, and the introduction of pathogen-reduction technologies (PRTs).

For the pathogens for which blood donors are currently screened, the risk of collecting an infectious donation that is not detectable by the currently used tests depends on the incidence of infection in blood donors and the length of the viral infection window (i.e., the time between infection, viraemia, and detection).

However, the last several decades have been characterized by the appearance of a significant number of emerging pathogens, and by the reappearance of infectious diseases with global impact, threatening transfusion safety. Blood donor screening tests may not be available for some of these pathogens.

Therefore, surveillance programs are a fundamental tool for monitoring new outbreaks of TTIs, for risk assessment, and for the implementation of strategies to guarantee transfusion safety.

These activities vary from country to country due to the different organisation of blood network surveillance systems, the strategic focus of transfusion safety programmes, and disease epidemiology.

As Guest Editors, we are excited to start a new challenge with this Special Issue. We hope that the document collection in this Issue will provide insights into the epidemiology of blood donors in different countries, as well as the best strategies for TTI risk reduction and ensuring blood donation safety, even during outbreaks from newly introduced or re-emerging pathogens.

The information can come from clinical practice and/or experimental research, as well as from accurate evaluations of data published in the literature.

We invite our colleagues to submit original research and review articles that provide interesting insights and new developments.

Dr. Vincenzo De Angelis
Dr. Ilaria Pati
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • transfusion-transmissible infections
  • epidemiological surveillance
  • emerging and re-emerging pathogens

Published Papers

This special issue is now open for submission.
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