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Pathogens, Volume 12, Issue 1

January 2023 - 149 articles

Cover Story: Chronic infection with the hepatitis B virus (HBV) affects an estimated 257 million people world-wide and can lead to serious diseases such as liver cirrhosis and hepatocellular carcinoma. HBV replication is not cytopathic, but some HBV proteins have direct carcinogenic effects. HBV-infected cells communicate with other cells, such as other hepatocytes, liver stromal cells, and innate and adaptive immune cells. They do so via both direct interaction and by secreting factors into their environment. Such factors may be small molecules, such as metabolites and viral and cellular proteins, but can also be more complex, such as virions, protein complexes, and extracellular vesicles. We review how the communication between the HBV-infected cells and cells in their environment forms a basis for viral persistence and HBV infection-related pathology. View this paper
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Articles (149)

  • Article
  • Open Access
12 Citations
3,296 Views
10 Pages

Patterns of ASFV Transmission in Domestic Pigs in Serbia

  • Dimitrije Glišić,
  • Vesna Milićević,
  • Ljubiša Veljović,
  • Bojan Milovanović,
  • Branislav Kureljušić,
  • Igor Đorđević,
  • Katarina Anđelković,
  • Jelena Petković and
  • Miroljub Dačić

16 January 2023

The first case of African swine fever in domestic pigs in Serbia was in 2019. The following year, the disease was confirmed in wild boar. Thenceforth, ASF has been continuously reported in both wild and domestic pigs. The outbreaks in domestic pigs c...

  • Article
  • Open Access
6 Citations
2,899 Views
11 Pages

Cross-Sectional Analysis of Human Papillomavirus Infection and Cytological Abnormalities in Brazilian Women

  • Luis Fernando Lasaro Mangieri,
  • Fernando Cezar-dos-Santos,
  • Kleber Paiva Trugilo,
  • Maria Angelica Ehara Watanabe,
  • Rafaela Roberta de Jaime Curti,
  • Eliza Pizarro Castilha,
  • Sarah Lott Moretto,
  • Caroline Yukari Motoori Fernandes,
  • Janaina Nicolau de Oliveira and
  • Karen Brajão de Oliveira

16 January 2023

The aim of this study was to determine the incidence of infections and cytological abnormalities and to investigate possible predisposing factors such as sociodemographic characteristics, sexual behavioral habits, and gynecological and obstetric back...

  • Article
  • Open Access
7 Citations
3,135 Views
17 Pages

15 January 2023

In this study, Listeria isolates (214) were characterized as follows: L. innocua (77.10%), L. monocytogenes (11.21%), L. welshimeri (5.61%), L. grayi (1.40%), L. seeligeri (0.93%), and L. species (3.73%) that were not identified at the species level,...

  • Systematic Review
  • Open Access
57 Citations
7,684 Views
14 Pages

Clinical Characteristics of Human Mpox (Monkeypox) in 2022: A Systematic Review and Meta-Analysis

  • Qi Liu,
  • Leiwen Fu,
  • Bingyi Wang,
  • Yinghui Sun,
  • Xinsheng Wu,
  • Xin Peng,
  • Yuwei Li,
  • Yi-Fan Lin,
  • Thomas Fitzpatrick and
  • Sten H. Vermund
  • + 1 author

15 January 2023

Since May 2022, large numbers of human mpox (previously known as monkeypox) cases have been reported in non-endemic regions. We conducted a systematic review and meta-analysis to elucidate clinical characteristics of the current mpox outbreak. Our sy...

  • Review
  • Open Access
3 Citations
4,792 Views
10 Pages

Is Vitamin D3 a Worthy Supplement Protecting against Secondary Infections in Dogs with Atopic Dermatitis?

  • Dorota Chrobak-Chmiel,
  • Anna Golke,
  • Ewelina Kwiecień,
  • Małgorzata J. Biegańska,
  • Kourou Dembele,
  • Małgorzata Dziekiewicz-Mrugasiewicz,
  • Michał Czopowicz,
  • Magdalena Kizerwetter-Świda and
  • Magdalena Rzewuska

15 January 2023

Canine atopic dermatitis (CAD) is a common, chronic, inflammatory skin disease in dogs worldwide. This disease often predisposes for secondary organisms overgrowth and skin infections with pathogens, such as Staphylococcus pseudintermedius and Malass...

  • Review
  • Open Access
22 Citations
6,189 Views
19 Pages

Limiting the Spread of Multidrug-Resistant Bacteria in Low-to-Middle-Income Countries: One Size Does Not Fit All

  • Rindala Saliba,
  • Jean-Ralph Zahar,
  • Georges Dabar,
  • Moussa Riachy,
  • Dolla Karam-Sarkis and
  • Rola Husni

14 January 2023

The spread of multidrug-resistant organisms (MDRO) is associated with additional costs as well as higher morbidity and mortality rates. Risk factors related to the spread of MDRO can be classified into four categories: bacterial, host-related, organi...

  • Article
  • Open Access
4 Citations
3,501 Views
18 Pages

14 January 2023

As generalist parasitoid wasps, Leptopilina heterotoma are highly successful on many species of fruit flies of the genus Drosophila. The parasitoids produce specialized multi-strategy extracellular vesicle (EV)-like structures in their venom. Proteom...

  • Article
  • Open Access
14 Citations
5,570 Views
20 Pages

14 January 2023

Ginger (Zingiber officinale Roscoe) is an important horticultural crop, valued for its culinary and medicinal properties. Fusarium yellows of ginger, caused by Fusarium oxysporum f. sp. zingiberi (Foz), is a devastating disease that has significantly...

  • Article
  • Open Access
2 Citations
2,741 Views
14 Pages

A More Comprehensive Clinical and Laboratory Characterization of 61 Acute HIV Infection Patients in Southwest China

  • Wu Shi,
  • Mei Yang,
  • Yinhao Wei,
  • Zhuoyun Tang,
  • Lan Luo,
  • Jielun Deng and
  • Chuanmin Tao

14 January 2023

Acute HIV infection (AHI), i.e., the early stage of HIV infection, plays an important role in immune system failure and HIV transmission, but most AHI patients are missed due to their non-specific symptoms. To facilitate the identification of patient...

  • Article
  • Open Access
5 Citations
2,981 Views
10 Pages

Using Zoos as Sentinels for Re-Emerging Arboviruses: Vector Surveillance during an Outbreak of Epizootic Hemorrhagic Disease at the Minnesota Zoo

  • Bethany L. McGregor,
  • Lindsey M. Reister-Hendricks,
  • Cale Nordmeyer,
  • Seth Stapleton,
  • Travis M. Davis and
  • Barbara S. Drolet

14 January 2023

Vector-borne disease prevalence is increasing at a time when surveillance capacity in the United States is decreasing. One way to address this surveillance deficiency is to utilize established infrastructure, such as zoological parks, to investigate...

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Pathogens - ISSN 2076-0817Creative Common CC BY license