You are currently on the new version of our website. Access the old version .

Diagnostics, Volume 13, Issue 8

April-2 2023 - 145 articles

Cover Story: The biochemical confirmation of hypercortisolism is complicated by the overlap with non-autonomous conditions and the practical difficulties of cortisol measurement. This limited narrative review focuses on the laboratory confirmation of hypercortisolism in patients with Cushing syndrome. Although analytically less specific, immunoassays remain cheap, quick, and mostly reliable. Cortisol metabolism however affects patient preparation, specimen selection (e.g., consideration of free cortisol, or late-night specimens and cessation of drugs), and method selection (e.g., mass spectrometry if abnormal metabolites are present). Urine steroid profiles and salivary cortisone may have a role in future guidelines as technology and costs improve. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (145)

  • Article
  • Open Access
7 Citations
2,946 Views
10 Pages

The Stability of the Anti-Müllerian Hormone in Serum and Plasma Samples under Various Preanalytical Conditions

  • Radana Vrzáková,
  • Václav Šimánek,
  • Ondřej Topolčan,
  • Vladimír Vurm,
  • David Slouka and
  • Radek Kučera

The anti-Müllerian hormone (AMH) is a glycoprotein that plays an important role in prenatal sex differentiation. It is used as a biomarker in polycystic ovary syndrome (PCOS) diagnostics, as well as for estimating an individual’s ovarian reserve and...

  • Article
  • Open Access
5 Citations
2,368 Views
14 Pages

Approximately 32–42% of very preterm infants develop minor motor abnormalities. Earlier diagnosis soon after birth is urgently needed because the first two years of life represent a critical window of opportunity for early neuroplasticity in in...

  • Review
  • Open Access
15 Citations
3,680 Views
14 Pages

Crohn’s disease (CD) is a chronic inflammatory disorder characterized by a transmural inflammation that may involve any part of the gastrointestinal tract. An evaluation of small bowel involvement, allowing recognition of disease extent and sev...

  • Article
  • Open Access
76 Citations
9,535 Views
21 Pages

Polycystic Ovary Syndrome Detection Machine Learning Model Based on Optimized Feature Selection and Explainable Artificial Intelligence

  • Hela Elmannai,
  • Nora El-Rashidy,
  • Ibrahim Mashal,
  • Manal Abdullah Alohali,
  • Sara Farag,
  • Shaker El-Sappagh and
  • Hager Saleh

Polycystic ovary syndrome (PCOS) has been classified as a severe health problem common among women globally. Early detection and treatment of PCOS reduce the possibility of long-term complications, such as increasing the chances of developing type 2...

  • Article
  • Open Access
7 Citations
2,653 Views
11 Pages

The Prevalence of Multidrug-Resistant Enterobacteriaceae among Neonates in Kuwait

  • Rehab Zafer Alajmi,
  • Wadha Ahmed Alfouzan and
  • Abu Salim Mustafa

Increasing numbers of neonates with serious bacterial infections, due to resistant bacteria, are associated with considerable morbidity and mortality rates. The aim of this study was to evaluate the prevalence of drug-resistant Enterobacteriaceae in...

  • Review
  • Open Access
6 Citations
3,158 Views
23 Pages

Myocardial Recovery

  • Nikolaos Chrysakis,
  • Andrew Xanthopoulos,
  • Dimitrios Magouliotis,
  • Randall C. Starling,
  • Stavros G. Drakos,
  • Filippos Triposkiadis and
  • John Skoularigis

In this paper, the feasibility of myocardial recovery is analyzed through a literature review. First, the phenomena of remodeling and reverse remodeling are analyzed, approached through the physics of elastic bodies, and the terms myocardial depressi...

  • Article
  • Open Access
55 Citations
6,247 Views
16 Pages

A Transfer Learning Approach for Clinical Detection Support of Monkeypox Skin Lesions

  • Maram Fahaad Almufareh,
  • Samabia Tehsin,
  • Mamoona Humayun and
  • Sumaira Kausar

Monkeypox (MPX) is a disease caused by monkeypox virus (MPXV). It is a contagious disease and has associated symptoms of skin lesions, rashes, fever, and respiratory distress lymph swelling along with numerous neurological distresses. This can be a d...

  • Review
  • Open Access
8 Citations
4,735 Views
24 Pages

Craniovertebral Junction Instability after Oncological Resection: A Narrative Review

  • Malte Ottenhausen,
  • Elena Greco,
  • Giacomo Bertolini,
  • Andrea Gerosa,
  • Salvatore Ippolito,
  • Erik H. Middlebrooks,
  • Graziano Serrao,
  • Maria Grazia Bruzzone,
  • Francesco Costa and
  • Paolo Ferroli
  • + 1 author

The craniovertebral junction (CVJ) is a complex transition area between the skull and cervical spine. Pathologies such as chordoma, chondrosarcoma and aneurysmal bone cysts may be encountered in this anatomical area and may predispose individuals to...

  • Article
  • Open Access
2,282 Views
10 Pages

Analysis of Corneal Deformation in Paediatric Patients Affected by Maturity Onset Diabetes of the Young Type 2

  • Michele Lanza,
  • Enza Mozzillo,
  • Rosa Boccia,
  • Ludovica Fedi,
  • Francesca Di Candia,
  • Nadia Tinto,
  • Paolo Melillo,
  • Francesca Simonelli and
  • Adriana Franzese

Background: To evaluate corneal deformation in Maturity Onset Diabetes of the Young type 2 (MODY2), paediatric subjects were analysed using a Scheimpflug-based device. The purpose of this analysis was to find new biomarkers for MODY2 disease and to g...

  • Systematic Review
  • Open Access
4 Citations
3,742 Views
13 Pages

Effectiveness of Using the FreeStyle Libre® System for Monitoring Blood Glucose during the COVID-19 Pandemic in Diabetic Individuals: Systematic Review

  • Luelia Teles Jaques-Albuquerque,
  • Elzi dos Anjos-Martins,
  • Luiza Torres-Nunes,
  • Ana Gabriellie Valério-Penha,
  • Ana Carolina Coelho-Oliveira,
  • Viviani Lopes da Silva Sarandy,
  • Aline Reis-Silva,
  • Adérito Seixas,
  • Mario Bernardo-Filho and
  • Redha Taiar
  • + 1 author

Background: Artificial Intelligence (AI) is an area of computer science/engineering that is aiming to spread technological systems. The COVID-19 pandemic caused economic and public health turbulence around the world. Among the many possibilities for...

of 15

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Diagnostics - ISSN 2075-4418