Life, Volume 14, Issue 11
2024 November - 177 articles
Cover Story: In this research, the author briefly reviewed the molecular pathway of hyperlipidemia in dogs, examining ApoE, LPL, and ApoA-1 in particular, through a pilot study that examined eleven client-owned dogs. The research reported that triglycerides showed a strong positive correlation with thigh circumference in both sides consistently (left, R = 0.711, p-value = 0.014, right, R = 0.749, p-value = 0.008) and total cholesterol in only one side (right, R = 0.776, p-value = 0.005), even though the thorax/thigh circumference ratio failed to be a new indicator that was comparable to the waist/hip circumference ratio in humans. A larger scale of follow up study utilizing the single-cell RNA technique would elucidate the hyperlipidemia molecular pathway of dogs by comparing human and dog ApoE mRNA concentrations at the tissue level individually. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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