- Article
Celecoxib, a Non-Steroidal Anti-Inflammatory Drug, Exerts a Toxic Effect on Human Melanoma Cells Grown as 2D and 3D Cell Cultures
- Alessandro Venuta,
- Rosarita Nasso,
- Armando Gisonna,
- Roberta Iuliano,
- Sara Montesarchio,
- Vittoria Acampora,
- Leandra Sepe,
- Angelica Avagliano,
- Rosaria Arcone and
- Maria Rosaria Ruocco
Cutaneous melanoma (CM) remains one of the leading causes of tumor mortality due to its high metastatic spread. CM growth is influenced by inflammation regulated by prostaglandins (PGs) whose synthesis is catalyzed by cyclooxygenases (COXs). COX inhi...

