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Life, Volume 13, Issue 5

May 2023 - 159 articles

Cover Story: Cinnamon aqueous extract has been tested in different studies to evaluate its possible use as an anti-cancer compound. In vitro and in vivo experiments seem to confirm that it acts on various cellular pathways, contributing to down-regulating the activity of molecules that stimulate the proliferation and survival of cells such as the transcription factors NF-KB and AP-1, COX-2, dihydrofolate reductase and pro-angiogenic substances such as VEGF, while up-regulating the function of immune cells against tumors, such as cytotoxic CD8+ T cells. In hematological malignancies, the aqueous extract of cinnamon has been studied to understand its potential use, alone or in combination with traditional drugs such as doxorubicin, to treat patients. This review collects the main studies on this topic. View this paper
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Articles (159)

  • Article
  • Open Access
4 Citations
5,248 Views
10 Pages

Nasal Patency in Sitting, Supine, and Prone Positions in Individuals with and without Allergic Rhinitis

  • Yun-Ting Wang,
  • Yao-Te Tsai,
  • Cheng-Ming Hsu,
  • Ming-Shao Tsai,
  • Hsin-Yi Tsai and
  • Geng-He Chang

22 May 2023

(1) Background: Physiological changes in nasal patency in response to posture contribute to sleep-related problems. Previously, we reported that the supine and prone positions cause a significant decrease in nasal patency in subjective and objective...

  • Article
  • Open Access
10 Citations
2,849 Views
13 Pages

HMGA1 and FOXM1 Cooperate to Promote G2/M Cell Cycle Progression in Cancer Cells

  • Qingfang Zheng,
  • Ziyang Luo,
  • Mingjun Xu,
  • Shazhou Ye,
  • Yuxin Lei and
  • Yang Xi

22 May 2023

HMGA1 is a chromatin-binding protein and performs its biological function by remodeling chromatin structure or recruiting other transcription factors. However, the role of abnormally high level of HMGA1 in cancer cells and its regulatory mechanism st...

  • Article
  • Open Access
10 Citations
5,908 Views
16 Pages

Effects of High-Intensity Functional Training (HIFT) on the Functional Capacity, Frailty, and Physical Condition of Older Adults with Mild Cognitive Impairment: A Blind Randomized Controlled Clinical Trial

  • Yulieth Rivas-Campo,
  • Agustín Aibar-Almazán,
  • Diego Fernando Afanador-Restrepo,
  • Patricia Alexandra García-Garro,
  • Gloria Cecilia Vega-Ávila,
  • Carlos Rodríguez-López,
  • Yolanda Castellote-Caballero,
  • María del Carmen Carcelén-Fraile and
  • María Leyre Lavilla-Lerma

21 May 2023

Physical exercise has been established as an intervention in the integral approach for the physical, functional, and social health of older adults. The objective of this study was to determine the effects of a high-intensity functional training (HIFT...

  • Article
  • Open Access
6 Citations
3,471 Views
22 Pages

21 May 2023

The main goal of this study was to analyze the reproductive patterns of edible dormouse (Glis glis) populations in the northeast of the Iberian Peninsula using an 18-year period of data obtained from nest boxes collected between 2004 and 2021. The av...

  • Article
  • Open Access
1 Citations
2,708 Views
15 Pages

21 May 2023

Luciferases from copepods Metridia longa and Gaussia princeps are successfully used as bioluminescent reporters for in vivo and in vitro assays. Here, we report the minimal sequence of copepod luciferases required for bioluminescence activity that wa...

  • Brief Report
  • Open Access
4 Citations
2,400 Views
8 Pages

20 May 2023

Airborne-mediated microbial diseases represent one of the major challenges to public health. Ultraviolet C radiation (UVC) is among the different sanitation techniques useful to reduce the risk of infection in healthcare facilities. Previous studies...

  • Systematic Review
  • Open Access
20 Citations
6,936 Views
31 Pages

Non-Invasive Brain Stimulation for the Modulation of Aggressive Behavior—A Systematic Review of Randomized Sham-Controlled Studies

  • Antony Casula,
  • Bianca M. Milazzo,
  • Gabriella Martino,
  • Alessandro Sergi,
  • Chiara Lucifora,
  • Francesco Tomaiuolo,
  • Angelo Quartarone,
  • Michael A. Nitsche and
  • Carmelo M. Vicario

20 May 2023

Intro: Aggressive behavior represents a significant public health issue, with relevant social, political, and security implications. Non-invasive brain stimulation (NIBS) techniques may modulate aggressive behavior through stimulation of the prefront...

  • Article
  • Open Access
16 Citations
4,896 Views
14 Pages

Biologic Therapies Decrease Disease Severity and Improve Depression and Anxiety Symptoms in Psoriasis Patients

  • Teodora-Larisa Timis,
  • Lehel Beni,
  • Teodora Mocan,
  • Ioan-Alexandru Florian and
  • Remus-Ioan Orasan

19 May 2023

Background: Psoriasis is an immune-mediated chronic skin disease that is associated with a significant psychological burden. A newer line of therapy is represented by biologic agents. Our study aimed to evaluate the effect of biologic therapies in th...

  • Article
  • Open Access
8 Citations
4,287 Views
14 Pages

Association of Low Arousal Threshold Obstructive Sleep Apnea Manifestations with Body Fat and Water Distribution

  • Wen-Hua Hsu,
  • Cheng-Chang Yang,
  • Cheng-Yu Tsai,
  • Arnab Majumdar,
  • Kang-Yun Lee,
  • Po-Hao Feng,
  • Chien-Hua Tseng,
  • Kuan-Yuan Chen,
  • Jiunn-Horng Kang and
  • Hsin-Chien Lee
  • + 3 authors

19 May 2023

Obstructive sleep apnea (OSA) with a low arousal threshold (low-ArTH) phenotype can cause minor respiratory events that exacerbate sleep fragmentation. Although anthropometric features may affect the risk of low-ArTH OSA, the associations and underly...

  • Article
  • Open Access
24 Citations
4,845 Views
18 Pages

Chemical Characterization and Evaluation of Antimicrobial Properties of the Wild Medicinal Mushroom Ganoderma lucidum Growing in Northern Moroccan Forests

  • El Hadi Erbiai,
  • Benoutman Amina,
  • Abbassi Kaoutar,
  • Rabah Saidi,
  • Zouhaire Lamrani,
  • Eugénia Pinto,
  • Joaquim C. G. Esteves da Silva,
  • Abdelfettah Maouni and
  • Luís Pinto da Silva

19 May 2023

Ganoderma lucidum is an extensively famous medicinal mushroom distributed worldwide. Despite being widely grown in Moroccan forests, there are no studies on its nutritional, nutraceutical and pharmaceutical values. Herein, the objective of this study...

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Life - ISSN 2075-1729