You are currently viewing a new version of our website. To view the old version click .
MDPIMDPI
Search all articles
Cancers
Submit to Cancers

Cancers, Volume 16, Issue 24

December-2 2024 - 164 articles

Cover Story: Exosomes, small extracellular vesicles, play a crucial role in intercellular communication. Cancer cell-derived exosomes exhibit tumorigenic properties, modulating the tumor microenvironment and promoting metastatic signaling in distant cells. This study aims to decipher the molecular profile and interactome of lung adenocarcinoma A549 cell-derived exosomes using multi-omics and bioinformatics approaches. We isolated and characterized exosomes from A549 cells, and through high-throughput proteomic and miRNA profiling, identified key molecules and their roles in recipient cell physiology. Comparative miRNA profiling with normal lung fibroblast (MRC-5) exosomes revealed tumor-associated miRNAs with potential further exploration, advancing our understanding of exosomal molecular components. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (164)

  • Systematic Review
  • Open Access
4 Citations
6,288 Views
24 Pages
Download PDF

The Effect of Resistance and/or Aerobic Training on Quality of Life, Fitness, and Body Composition in Prostate Cancer Patients—A Systematic Review and Meta-Analysis

  • Shimon Kempin,
  • Alexander Buchner,
  • Sarah Frederike Brose,
  • Nina Schmidt-Hegemann,
  • Matthias May,
  • Ingmar Wolff,
  • Anton Kravchuk,
  • Christian Stief,
  • Sabine D. Brookman-May and
  • Benazir Enzinger
Cancers2024, 16(24), 4286;https://doi.org/10.3390/cancers16244286

23 December 2024

Background: Prostate cancer (PC) and its treatment are often associated with side effects such as fatigue, muscle loss, and diminished quality of life (QoL). Physical exercise, particularly resistance training (RT) and aerobic training (AT), has been...

Full Article
  • Article
  • Open Access
3 Citations
1,618 Views
15 Pages
Download PDF

Discoidin Domain Receptor 2 Contributes to Breast Cancer Progression and Chemoresistance by Interacting with Collagen Type I

  • Ai Sato,
  • Kiyoshi Takagi,
  • Momoka Yoshida,
  • Mio Yamaguchi-Tanaka,
  • Mikoto Sagehashi,
  • Yasuhiro Miki,
  • Minoru Miyashita and
  • Takashi Suzuki
Cancers2024, 16(24), 4285;https://doi.org/10.3390/cancers16244285

23 December 2024

Background: Chemoresistance is an important issue to be solved in breast cancer. It is well known that the content and morphology of collagens in tumor tissues are drastically altered following chemotherapy, and discoidin domain receptor 2 (DDR2) is...

Full Article
  • Article
  • Open Access
3 Citations
1,548 Views
14 Pages
Download PDF

Diffusion-Weighted MRI and Human Papillomavirus (HPV) Status in Oropharyngeal Cancer

  • Heleen Bollen,
  • Rüveyda Dok,
  • Frederik De Keyzer,
  • Sarah Deschuymer,
  • Annouschka Laenen,
  • Johannes Devos,
  • Vincent Vandecaveye and
  • Sandra Nuyts
Cancers2024, 16(24), 4284;https://doi.org/10.3390/cancers16244284

23 December 2024

Background: This study aimed to explore the differences in quantitative diffusion-weighted (DW) MRI parameters in oropharyngeal squamous cell carcinoma (OPC) based on Human Papillomavirus (HPV) status before and during radiotherapy (RT). Methods: Ech...

Full Article
  • Article
  • Open Access
1,891 Views
14 Pages
Download PDF

Clinical Introduction of Stem Cell Sparing Radiotherapy to Reduce the Risk of Xerostomia in Patients with Head and Neck Cancer

  • Maria I. van Rijn-Dekker,
  • Arjen van der Schaaf,
  • Sanne W. Nienhuis,
  • Antoinette S. Arents-Huls,
  • Rachel B. Ger,
  • Olga Hamming-Vrieze,
  • Frank J. P. Hoebers,
  • Mischa de Ridder,
  • Sabrina Vigorito and
  • Ellen M. Zwijnenburg
  • + 3 authors
Cancers2024, 16(24), 4283;https://doi.org/10.3390/cancers16244283

23 December 2024

Background/Objectives: Studies have shown that dose to the parotid gland stem cell rich (SCR) regions should be reduced to lower the risk of xerostomia after radiotherapy (RT). This study aimed to assess whether stem cell sparing (SCS)-RT can be adop...

Full Article
  • Article
  • Open Access
5 Citations
2,105 Views
18 Pages
Download PDF

Cardiotoxicity in Breast Cancer: Impact of Clinical Classifications and Treatment on Heart Health

  • Sergiu Ioan Murg,
  • Loredana Matiș,
  • Andrada Florina Moldovan,
  • Andrada Florina Schwarz-Madar,
  • Daniela Florina Trifan,
  • Timea Claudia Ghitea and
  • Mircea Ioachim Popescu
Cancers2024, 16(24), 4281;https://doi.org/10.3390/cancers16244281

23 December 2024

Background/Objectives: Cardio-oncology has become essential in addressing cardiovascular complications from cancer therapies. While advancements in treatments have improved survival rates, they also increase cardiovascular risks. This study evaluates...

Full Article
  • Article
  • Open Access
1 Citations
1,734 Views
12 Pages
Download PDF

Association Between Reconstruction Technique and Clinical Outcomes in Advanced Gastric Cancer Patients Undergoing Proximal Gastrectomy

  • Katarzyna Sędłak,
  • Karol Rawicz-Pruszyński,
  • Zuzanna Pelc,
  • Radosław Mlak,
  • Katarzyna Gęca,
  • Magdalena Skórzewska,
  • Krzysztof Zinkiewicz,
  • Katarzyna Chawrylak and
  • Wojciech P. Polkowski
Cancers2024, 16(24), 4282;https://doi.org/10.3390/cancers16244282

23 December 2024

Background: There is an upward shift in the incidence and localization of gastric cancer (GC). Proximal gastrectomy (PG) has been advocated as an alternative operation for upper-third GC. An uneventful postoperative course is currently measured using...

Full Article
  • Feature Paper
  • Article
  • Open Access
4 Citations
6,075 Views
9 Pages
Download PDF

Effectiveness of the Korean National Cancer Screening Program in Reducing Colorectal Cancer Mortality

  • Hyeon Ji Lee,
  • Kyeongmin Lee,
  • Byung Chang Kim,
  • Jae Kwan Jun,
  • Kui Son Choi and
  • Mina Suh
Cancers2024, 16(24), 4278;https://doi.org/10.3390/cancers16244278

23 December 2024

Background: Whether colorectal cancer (CRC) screening with a fecal immunochemical test (FIT) reduces mortality remains unclear. In South Korea, CRC screening with a FIT for individuals aged ≥ 50 years has been part of the Korean National Cancer Sc...

Full Article
  • Systematic Review
  • Open Access
3,098 Views
21 Pages
Download PDF

Sentinel Lymph Node Biopsy: Is There a Role in Non-Melanoma Skin Cancer? A Systematic Review

  • Lorenzo Borgognoni,
  • Pietro Susini,
  • Gianni Gerlini,
  • Paola Brandani,
  • Vanni Giannotti and
  • Serena Sestini
Cancers2024, 16(24), 4279;https://doi.org/10.3390/cancers16244279

23 December 2024

Background/Objectives: Sentinel Lymph Node Biopsy (SLNB) aims at identifying clinically occult nodal metastases. It is the standard staging procedure for patients with T1b to T4 primary cutaneous melanoma. Moreover, it is recommended whenever the ris...

Full Article
  • Article
  • Open Access
1,776 Views
13 Pages
Download PDF

Efficacy of Neoadjuvant Hypofractionated Chemoradiotherapy in Elderly Patients with Locally Advanced Rectal Cancer: A Single-Center Retrospective Analysis

  • Jae Seung Kim,
  • Jaram Lee,
  • Hyeung-min Park,
  • Soo Young Lee,
  • Chang Hyun Kim and
  • Hyeong Rok Kim
Cancers2024, 16(24), 4280;https://doi.org/10.3390/cancers16244280

23 December 2024

Background/Objectives: The application of long-course chemoradiotherapy (LCRT) in elderly patients with locally advanced rectal cancer (LARC) can be challenging due to increased risks of complications associated with comorbidities and reduced functio...

Full Article

of 17

Go to next page

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Cancers - ISSN 2072-6694
Imprint
Download Flyer