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Micromachines, Volume 15, Issue 9
September 2024 - 117 articles
Cover Story: Inertial focusing-based Lab-on-Chip systems offer a promising solution for efficient cell sorting thus meeting the World Health Organization's ASSURED criteria (Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment-free, and Deliverable to end-users). This review explores how inertial focusing in spiral microchannels supports cell sorting, examining the effects of different cross-sectional geometries—rectangular, trapezoidal, triangular, and hybrid—on particle focusing and sorting efficiency. By balancing the primary and secondary flow forces, spiral channels enable high-throughput and efficient filtration across varying particle sizes. Additionally, this work addresses various materials and prototyping techniques, providing insights to guide the design and selection of spiral geometries and materials based on application-specific particles. View this paper
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Micromachines - ISSN 2072-666XCreative Common CC BY license