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Micromachines, Volume 8, Issue 4

2017 April - 39 articles

Cover Story: A fanciful ball design has been used to demonstrate the 4D printing abilities of entrapped enzymes in photopolymerized hydrogels to mimic biological functions. Such tools are able to generate specific catalytic signals over time in response to environmental stimuli. Two examples of 4D printed tools are presented in this paper to illustrate progressions towards biosensing and biomimetic applications. The first one is based on the printing of the enzymatic couple glucose oxidase/peroxidase for the chemiluminescent detection of glucose; the second one uses printed alkaline phosphatase to generate in situ programmed and localized calcification of the printed object. View the paper
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Articles (39)

  • Article
  • Open Access
9 Citations
6,779 Views
9 Pages

19 April 2017

Biomedical coatings are used to promote the wear resistance and the biocompatibility of a mechanical heart valve. An orbital shaking test was proposed to assess the durability of the coatings by the amount material eroded by the surrounding fluid. Ho...

  • Review
  • Open Access
49 Citations
19,593 Views
24 Pages

Stencil Lithography for Scalable Micro- and Nanomanufacturing

  • Ke Du,
  • Junjun Ding,
  • Yuyang Liu,
  • Ishan Wathuthanthri and
  • Chang-Hwan Choi

19 April 2017

In this paper, we review the current development of stencil lithography for scalable micro- and nanomanufacturing as a resistless and reusable patterning technique. We first introduce the motivation and advantages of stencil lithography for large-are...

  • Article
  • Open Access
37 Citations
10,693 Views
12 Pages

Paper-Based Analytical Device for Zinc Ion Quantification in Water Samples with Power-Free Analyte Concentration

  • Hiroko Kudo,
  • Kentaro Yamada,
  • Daiki Watanabe,
  • Koji Suzuki and
  • Daniel Citterio

18 April 2017

Insufficient sensitivity is a general issue of colorimetric paper-based analytical devices (PADs) for trace analyte detection, such as metal ions, in environmental water. This paper demonstrates the colorimetric detection of zinc ions (Zn2+) on a pap...

  • Review
  • Open Access
55 Citations
15,641 Views
21 Pages

18 April 2017

Enzymes are extremely valuable tools for industrial, environmental, and biotechnological applications and there is a constant need for improving existing biological catalysts and for discovering new ones. Screening microbe or gene libraries is an eff...

  • Editorial
  • Open Access
9 Citations
5,242 Views
6 Pages

18 April 2017

The 2016 International Symposium of Flexible and Stretchable Electronics (ISFSE2016), co-sponsored by the Flexible Electronics Research Center, Huazhong University of Science and Technology (HUST) & State Key Laboratory of Digital Manufacturing a...

  • Article
  • Open Access
14 Citations
6,064 Views
13 Pages

18 April 2017

A novel micromanipulation technique of multi-objectives based on vibrating bubbles in an open chip environment is described in this paper. Bubbles were created in an aqueous medium by the thermal energy converted from a laser. When the piezoelectric...

  • Article
  • Open Access
9 Citations
5,699 Views
13 Pages

16 April 2017

In order to identify the influence of the vacuum environment on the performance of a comb-drive microscanner, and indicate the optimum pressure for enhancing its performance, a comb-drive microscanner fabricated on silicon-on-insulator (SOI) substrat...

  • Review
  • Open Access
71 Citations
15,075 Views
38 Pages

14 April 2017

Robust and inexpensive dry adhesives would have a multitude of potential applications, but replicating the impressive adhesive organs of many small animals has proved challenging. A substantial body of work has been produced in recent years which has...

  • Article
  • Open Access
4 Citations
6,083 Views
8 Pages

13 April 2017

It is meaningful to study the surface morphology of monocrystalline material, but there are few studies on the surface roughness of quartz. So, surface roughness of Z-cut quartz etched by pure ammonium bifluoride and ammonium bifluoride mixed with is...

  • Feature Paper
  • Review
  • Open Access
25 Citations
9,230 Views
18 Pages

The Use of Microfluidics in Cytotoxicity and Nanotoxicity Experiments

  • Scott C. McCormick,
  • Frederik H. Kriel,
  • Angela Ivask,
  • Ziqiu Tong,
  • Enzo Lombi,
  • Nicolas H. Voelcker and
  • Craig Priest

12 April 2017

Many unique chemical compounds and nanomaterials are being developed, and each one requires a considerable range of in vitro and/or in vivo toxicity screening in order to evaluate their safety. The current methodology of in vitro toxicological screen...

  • Review
  • Open Access
58 Citations
12,344 Views
17 Pages

The Self-Propulsion of the Spherical Pt–SiO2 Janus Micro-Motor

  • Jing Zhang,
  • Xu Zheng,
  • Haihang Cui and
  • Zhanhua Silber-Li

12 April 2017

The double-faced Janus micro-motor, which utilizes the heterogeneity between its two hemispheres to generate self-propulsion, has shown great potential in water cleaning, drug delivery in micro/nanofluidics, and provision of power for a novel micro-r...

  • Article
  • Open Access
12 Citations
6,634 Views
13 Pages

11 April 2017

Localized single cells can be lysed precisely and selectively using microbubbles optothermally generated by microsecond laser pulses. The shear stress from the microstreaming surrounding laser-induced microbubbles and direct contact with the surface...

  • Article
  • Open Access
60 Citations
14,201 Views
14 Pages

10 April 2017

A micro scanning mirror is an optical device used to scan laser beams which can be used for Light Detection and Ranging (LiDAR) in applications like unmanned driving or Unmanned Aerial Vehicle (UAV). The MEMS scanning mirror’s light-weight and low-po...

  • Article
  • Open Access
24 Citations
8,343 Views
15 Pages

Fluid Flow and Mixing Induced by AC Continuous Electrowetting of Liquid Metal Droplet

  • Qingming Hu,
  • Yukun Ren,
  • Weiyu Liu,
  • Xiaoming Chen,
  • Ye Tao and
  • Hongyuan Jiang

9 April 2017

In this work, we proposed a novel design of a microfluidic mixer utilizing the amplified Marangoni chaotic advection induced by alternating current (AC) continuous electrowetting of a metal droplet situated in electrolyte solution, due to the linear...

  • Article
  • Open Access
1 Citations
5,688 Views
12 Pages

A Suspended Six-Port Transformer-Based Power Divider for 2.4 GHz Applications

  • Wen-Hui Huang,
  • I-Yu Huang,
  • Wun-Hong Syu,
  • Chia-Lung Sung and
  • Chia-Hsu Hsieh

8 April 2017

This paper presents a transformer-based power divider with six-port suspending structure for 2.4 GHz wireless applications. The proposed power divider, which is featured with chip size (2.9 mm × 2.8 mm × 21 μm), was constructed by an 8-μm-thick Cu bo...

  • Article
  • Open Access
24 Citations
5,563 Views
13 Pages

5 April 2017

We developed a highly sensitive humidity sensor based on the combination of ultrahigh-frequency film bulk acoustic resonator (FBAR) and nano-assembled polyelectrolyte (PET) thin films. The water molecule absorption efficiency was optimized by forming...

  • Article
  • Open Access
65 Citations
6,757 Views
11 Pages

4 April 2017

Piezoelectric actuator (PEA) is an ideal microscale and nanoscale actuator because of its ultra-precision positioning resolution. However, the inherent hysteretic nonlinearity significantly degrades the PEA’s accuracy. The measured hysteresis of PEA...

  • Article
  • Open Access
38 Citations
7,647 Views
14 Pages

4 April 2017

In this paper, we propose a helical piezoelectric energy harvester, examine its application to clothes in the form of an energy harvesting garment, and analyze its design and characteristics. The helical harvester is composed of an elastic core and a...

  • Feature Paper
  • Article
  • Open Access
133 Citations
14,767 Views
10 Pages

1 April 2017

By modification of glasses with ultrafast laser radiation and subsequent wet-chemical etching (here named SLE = selective laser-induced etching), precise 3D structures have been produced, especially in quartz glass (fused silica), for more than a dec...

  • Article
  • Open Access
8 Citations
7,629 Views
19 Pages

1 April 2017

The design of a micromirror for biomedical applications requires multiple output responses to be optimized, given a set of performance parameters and constraints. This paper presents the parametric design optimization of an electrothermally actuated...

  • Article
  • Open Access
7 Citations
6,482 Views
11 Pages

A Feasibility Study on the Simultaneous Sensing of Turbidity and Chlorophyll a Concentration Using a Simple Optical Measurement Method

  • Ryota Isoyama,
  • Manami Taie,
  • Tomoaki Kageyama,
  • Masashi Miura,
  • Akihiro Maeda,
  • Akihiro Mori and
  • Sang-Seok Lee

1 April 2017

We have been developing a wireless sensor network system to monitor the quality of lake water in real time. It consists of a sensor module and a system module, which includes communication and power modules. We have focused on pH, turbidity and chlor...

  • Article
  • Open Access
41 Citations
9,212 Views
12 Pages

A Programmable Digital Microfluidic Assay for the Simultaneous Detection of Multiple Anti-Microbial Resistance Genes

  • Sumit Kalsi,
  • Samuel L. Sellars,
  • Carrie Turner,
  • J. Mark Sutton and
  • Hywel Morgan

1 April 2017

The rapid emergence of antimicrobial resistant bacteria requires the development of new diagnostic tests. Nucleic acid-based assays determine antimicrobial susceptibility by detecting genes that encode for the resistance. In this study, we demonstrat...

  • Article
  • Open Access
3 Citations
4,315 Views
7 Pages

1 April 2017

Herein we describe the vibration of a thin nickel film-coated microcantilever at resonance under an external magnetic field. The resonance frequency and the mechanical loss—experimentally observed while varying the magnetic field—closely follow the f...

  • Review
  • Open Access
36 Citations
9,460 Views
27 Pages

Nanomechanical Motion Transducers for Miniaturized Mechanical Systems

  • Taejoon Kouh,
  • M. Selim Hanay and
  • Kamil L. Ekinci

1 April 2017

Reliable operation of a miniaturized mechanical system requires that nanomechanical motion be transduced into electrical signals (and vice versa) with high fidelity and in a robust manner. Progress in transducer technologies is expected to impact num...

  • Article
  • Open Access
15 Citations
7,858 Views
11 Pages

1 April 2017

The surge in popularity of lab-on-chip applications has set a new challenge for the fabrication of prototyping devices, such as electrokinetic devices. In such devices, a micro-electrode is the key component. Currently, microelectromechanical systems...

  • Review
  • Open Access
191 Citations
21,693 Views
20 Pages

The Emerging Frontiers and Applications of High-Resolution 3D Printing

  • Mao Mao,
  • Jiankang He,
  • Xiao Li,
  • Bing Zhang,
  • Qi Lei,
  • Yaxiong Liu and
  • Dichen Li

1 April 2017

Over the past few decades, there has been an increasing interest in the fabrication of complex high-resolution three-dimensional (3D) architectures at micro/nanoscale. These architectures can be obtained through conventional microfabrication methods...

  • Article
  • Open Access
16 Citations
5,972 Views
12 Pages

29 March 2017

We present a novel electroosmotic micromixer that consists of arrays of direct current (DC) asymmetric electrode and asymmetric lateral structures. By embedding asymmetric electrode arrays on the top and bottom walls of a rectangular microchannel app...

  • Review
  • Open Access
19 Citations
11,378 Views
22 Pages

Aerogels for Optofluidic Waveguides

  • Yaprak Özbakır,
  • Alexandr Jonas,
  • Alper Kiraz and
  • Can Erkey

29 March 2017

Aerogels—solid materials keeping their internal structure of interconnected submicron-sized pores intact upon exchanging the pore liquid with a gas—were first synthesized in 1932 by Samuel Kistler. Overall, an aerogel is a special form of a highly po...

  • Article
  • Open Access
114 Citations
17,315 Views
9 Pages

Paper-Based Colorimetric Biosensor for Tear Glucose Measurements

  • Ellen Flávia Moreira Gabriel,
  • Paulo Tarso Garcia,
  • Flavio Marques Lopes and
  • Wendell Karlos Tomazelli Coltro

29 March 2017

This paper describes a paper-based colorimetric biosensor for measuring glucose concentration levels in human tear samples. Colorimetric biosensors were wax printed on paper platforms and modified with chitosan previously prepared in acetic acid. The...

  • Article
  • Open Access
25 Citations
5,794 Views
11 Pages

Design and Construction of a Micro-Tribotester for Precise In-Situ Wear Measurements

  • Oleksiy V. Penkov,
  • Mahdi Khadem,
  • Andy Nieto,
  • Tae-Hyeong Kim and
  • Dae-Eun Kim

28 March 2017

Extensive research efforts have been devoted to understand the complex mechanisms of wear with the aim to minimize wear in sliding systems. Improvements in the instruments used for the characterization of the wear phenomenon are required to enhance t...

  • Article
  • Open Access
38 Citations
9,264 Views
8 Pages

3D–4D Printed Objects: New Bioactive Material Opportunities

  • Céline A. Mandon,
  • Loïc J. Blum and
  • Christophe A. Marquette

27 March 2017

One of the main objectives of 3D printing in health science is to mimic biological functions. To reach this goal, a 4D printing might be added to 3D-printed objects which will be characterized by their abilities to evolve over time and under external...

  • Review
  • Open Access
91 Citations
14,437 Views
25 Pages

27 March 2017

The ability to create complex three-dimensional microstructures has reached an unprecedented level of sophistication in the last 15 years. For the most part, this is the result of a steady development of the additive manufacturing technique named two...

  • Article
  • Open Access
13 Citations
6,646 Views
10 Pages

Red Blood Cell Responses during a Long-Standing Load in a Microfluidic Constriction

  • Mitsuhiro Horade,
  • Chia-Hung Dylan Tsai,
  • Hiroaki Ito and
  • Makoto Kaneko

26 March 2017

Red blood cell responses during a long-standing load were experimentally investigated. With a high-speed camera and a high-speed actuator, we were able to manipulate cells staying inside a microfluidic constriction, and each cell was compressed due t...

  • Feature Paper
  • Article
  • Open Access
10 Citations
5,703 Views
11 Pages

25 March 2017

Microfluidic paper-based analytical devices (µPADs) have emerged as viable multiplexable platforms with the potential to transcend existing analytical techniques in resource-limited settings. µPADs are fabricated by patterning hydrophobic materials o...

  • Article
  • Open Access
16 Citations
7,123 Views
16 Pages

Large-Area Piezoelectric PVDF Fibers Fabricated by Near-Field Electrospinning with Multi-Spinneret Structures

  • Cheng-Tang Pan,
  • Kuo-Chang Tsai,
  • Shao-Yu Wang,
  • Chung-Kun Yen and
  • Yan-Liang Lin

24 March 2017

In the study, we improved the near-field electrospinning (NFES) by multi-spinnerets with a cylindrical collector to fabricate a large area permanent piezoelectric of polyvinylidene fluoride (PVDF) fibers array. We designed multi-spinnerets by using p...

  • Review
  • Open Access
117 Citations
16,911 Views
23 Pages

Microfluidic Technology for the Generation of Cell Spheroids and Their Applications

  • Raja K. Vadivelu,
  • Harshad Kamble,
  • Muhammad J. A. Shiddiky and
  • Nam-Trung Nguyen

23 March 2017

A three-dimensional (3D) tissue model has significant advantages over the conventional two-dimensional (2D) model. A 3D model mimics the relevant in-vivo physiological conditions, allowing a cell culture to serve as an effective tool for drug discove...

  • Article
  • Open Access
14 Citations
4,613 Views
9 Pages

23 March 2017

A two-dimensional (2D) magnetic field sensor consisting of four silicon magnetic sensitive transistors (SMSTs) with similar characteristics is presented in this paper. By use of micro-electromechanical systems (MEMS) and integrated packaging technolo...

  • Article
  • Open Access
10 Citations
4,304 Views
11 Pages

23 March 2017

Damage to mechanical components caused by wear is considered to be an important issue for mechanical engineers. For the purpose of wear resistance, it is necessary to improve the material properties of the mechanical elements. Furthermore, low fricti...

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Micromachines - ISSN 2072-666X