Next Article in Journal
Ultrahigh-Throughput Improvement and Discovery of Enzymes Using Droplet-Based Microfluidic Screening
Next Article in Special Issue
Monitoring Acid–Base Titrations on Wax Printed Paper Microzones Using a Smartphone
Previous Article in Journal
The Exploration for an Appropriate Vacuum Level for Performance Enhancement of a Comb-Drive Microscanner
Previous Article in Special Issue
Paper-Based Colorimetric Biosensor for Tear Glucose Measurements
Open AccessArticle

Paper-Based Analytical Device for Zinc Ion Quantification in Water Samples with Power-Free Analyte Concentration

Department of Applied Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Kanagawa, Japan
*
Author to whom correspondence should be addressed.
Academic Editors: Frank A. Gomez and Carlos D. Garcia
Micromachines 2017, 8(4), 127; https://doi.org/10.3390/mi8040127
Received: 25 March 2017 / Revised: 11 April 2017 / Accepted: 13 April 2017 / Published: 18 April 2017
(This article belongs to the Special Issue Paper Microfluidics: Fundamental Studies and Applications)
Insufficient sensitivity is a general issue of colorimetric paper-based analytical devices (PADs) for trace analyte detection, such as metal ions, in environmental water. This paper demonstrates the colorimetric detection of zinc ions (Zn2+) on a paper-based analytical device with an integrated analyte concentration system. Concentration of Zn2+ ions from an enlarged sample volume (1 mL) has been achieved with the aid of a colorimetric Zn2+ indicator (Zincon) electrostatically immobilized onto a filter paper substrate in combination with highly water-absorbent materials. Analyte concentration as well as sample pretreatment, including pH adjustment and interferent masking, has been elaborated. The resulting device enables colorimetric quantification of Zn2+ in environmental water samples (tap water, river water) from a single sample application. The achieved detection limit of 0.53 μM is a significant improvement over that of a commercial colorimetric Zn2+ test paper (9.7 μM), demonstrating the efficiency of the developed analyte concentration system not requiring any equipment. View Full-Text
Keywords: colorimetry; analyte enrichment; PAD; inkjet printing; 3D-printing colorimetry; analyte enrichment; PAD; inkjet printing; 3D-printing
Show Figures

Figure 1

MDPI and ACS Style

Kudo, H.; Yamada, K.; Watanabe, D.; Suzuki, K.; Citterio, D. Paper-Based Analytical Device for Zinc Ion Quantification in Water Samples with Power-Free Analyte Concentration. Micromachines 2017, 8, 127. https://doi.org/10.3390/mi8040127

AMA Style

Kudo H, Yamada K, Watanabe D, Suzuki K, Citterio D. Paper-Based Analytical Device for Zinc Ion Quantification in Water Samples with Power-Free Analyte Concentration. Micromachines. 2017; 8(4):127. https://doi.org/10.3390/mi8040127

Chicago/Turabian Style

Kudo, Hiroko; Yamada, Kentaro; Watanabe, Daiki; Suzuki, Koji; Citterio, Daniel. 2017. "Paper-Based Analytical Device for Zinc Ion Quantification in Water Samples with Power-Free Analyte Concentration" Micromachines 8, no. 4: 127. https://doi.org/10.3390/mi8040127

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop