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Toxins, Volume 7, Issue 4

April 2015 - 22 articles

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Articles (22)

  • Review
  • Open Access
143 Citations
14,242 Views
22 Pages

20 April 2015

Harmful cyanobacterial blooms have adversely impacted human and animal health for thousands of years. Recently, the health impacts of harmful cyanobacteria blooms are becoming more frequently detected and reported. However, reports of human and anima...

  • Article
  • Open Access
13 Citations
9,062 Views
19 Pages

The Key Role of Peltate Glandular Trichomes in Symbiota Comprising Clavicipitaceous Fungi of the Genus Periglandula and Their Host Plants

  • Ulrike Steiner,
  • Sabine Hellwig,
  • Mahalia A. Ahimsa-Müller,
  • Nicola Grundmann,
  • Shu-Ming Li,
  • Christel Drewke and
  • Eckhard Leistner

16 April 2015

Clavicipitaceous fungi producing ergot alkaloids were recently discovered to be epibiotically associated with peltate glandular trichomes of Ipomoea asarifolia and Turbina corymbosa, dicotyledonous plants of the family Convolvulaceae. Mediators of t...

  • Article
  • Open Access
11 Citations
6,322 Views
17 Pages

15 April 2015

The separation of PSP toxins using liquid chromatography with a post-column oxidation fluorescence detection method was performed with different matrices. The separation of PSP toxins depends on several factors, and it is crucial to take into account...

  • Article
  • Open Access
55 Citations
7,200 Views
14 Pages

Dietary l-Arginine Supplementation Protects Weanling Pigs from Deoxynivalenol-Induced Toxicity

  • Li Wu,
  • Peng Liao,
  • Liuqin He,
  • Zemeng Feng,
  • Wenkai Ren,
  • Jie Yin,
  • Jielin Duan,
  • Tiejun Li and
  • Yulong Yin

15 April 2015

This study was conducted to determine the positive effects of dietary supplementation with l-arginine (Arg) on piglets fed a deoxynivalenol (DON)-contaminated diet. A total of eighteen, 28-day-old healthy weanling pigs were randomly assigned into one...

  • Review
  • Open Access
89 Citations
11,485 Views
30 Pages

Genetics, Genomics and Evolution of Ergot Alkaloid Diversity

  • Carolyn A. Young,
  • Christopher L. Schardl,
  • Daniel G. Panaccione,
  • Simona Florea,
  • Johanna E. Takach,
  • Nikki D. Charlton,
  • Neil Moore,
  • Jennifer S. Webb and
  • Jolanta Jaromczyk

14 April 2015

The ergot alkaloid biosynthesis system has become an excellent model to study evolutionary diversification of specialized (secondary) metabolites. This is a very diverse class of alkaloids with various neurotropic activities, produced by fungi in sev...

  • Article
  • Open Access
23 Citations
7,271 Views
21 Pages

Role of Acidic Residues in Helices TH8–TH9 in Membrane Interactions of the Diphtheria Toxin T Domain

  • Chiranjib Ghatak,
  • Mykola V. Rodnin,
  • Mauricio Vargas-Uribe,
  • Andrew J. McCluskey,
  • Jose C. Flores-Canales,
  • Maria Kurnikova and
  • Alexey S. Ladokhin

14 April 2015

The pH-triggered membrane insertion of the diphtheria toxin translocation domain (T domain) results in transferring the catalytic domain into the cytosol, which is relevant to potential biomedical applications as a cargo-delivery system. Protonation...

  • Article
  • Open Access
31 Citations
7,155 Views
20 Pages

Dose-Dependent Effects on Sphingoid Bases and Cytokines in Chickens Fed Diets Prepared with Fusarium Verticillioides Culture Material Containing Fumonisins

  • Bertrand Grenier,
  • Heidi E. Schwartz-Zimmermann,
  • Sylvia Caha,
  • Wulf Dieter Moll,
  • Gerd Schatzmayr and
  • Todd J. Applegate

13 April 2015

In chickens, the effect of mycotoxins, especially fumonisins (FB), in the gastrointestinal tract (GIT) is not well documented. Thus, this study in broiler chicks determined the effects of consuming diets prepared with Fusarium verticillioides culture...

  • Article
  • Open Access
85 Citations
12,178 Views
29 Pages

9 April 2015

The more frequent occurrence of both marine and freshwater toxic algal blooms and recent problems with new toxic events have increased the risk for illness and negatively impacted sustainable public access to safe shellfish and recreational waters in...

  • Article
  • Open Access
16 Citations
9,383 Views
18 Pages

Binding Studies on Isolated Porcine Small Intestinal Mucosa and in vitro Toxicity Studies Reveal Lack of Effect of C. perfringens Beta-Toxin on the Porcine Intestinal Epithelium

  • Simone Roos,
  • Marianne Wyder,
  • Ahmet Candi,
  • Nadine Regenscheit,
  • Christina Nathues,
  • Filip Van Immerseel and
  • Horst Posthaus

9 April 2015

Beta-toxin (CPB) is the essential virulence factor of C. perfringens type C causing necrotizing enteritis (NE) in different hosts. Using a pig infection model, we showed that CPB targets small intestinal endothelial cells. Its effect on the porcine...

  • Article
  • Open Access
23 Citations
8,012 Views
14 Pages

8 April 2015

In this post-hoc analysis of the ULIS-II study, we investigated factors influencing person-centred goal setting and achievement following botulinum toxin-A (BoNT-A) treatment in 456 adults with post-stroke upper limb spasticity (ULS). Patients with p...

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Toxins - ISSN 2072-6651