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Toxins, Volume 6, Issue 4

April 2014 - 21 articles

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Articles (21)

  • Article
  • Open Access
14 Citations
7,181 Views
13 Pages

10 April 2014

Ochratoxin A (OTA) is a mycotoxin produced by different Aspergillus and Penicillium species. Since its mechanism of action is not fully understood yet, it is important to gain further insight into different interactions of OTA at the molecular level....

  • Article
  • Open Access
36 Citations
7,509 Views
17 Pages

Systemic Growth of F. graminearum in Wheat Plants and Related Accumulation of Deoxynivalenol

  • Antonio Moretti,
  • Giuseppe Panzarini,
  • Stefania Somma,
  • Claudio Campagna,
  • Stefano Ravaglia,
  • Antonio F. Logrieco and
  • Michele Solfrizzo

10 April 2014

Fusarium head blight (FHB) is an important disease of wheat worldwide caused mainly by Fusarium graminearum (syn. Gibberella zeae). This fungus can be highly aggressive and can produce several mycotoxins such as deoxynivalenol (DON), a well known har...

  • Article
  • Open Access
17 Citations
9,516 Views
21 Pages

3 April 2014

We developed a microarray based on 2895 unique transcripts assembled from 15,000 cDNA sequences from the European corn borer (Ostrinia nubilalis) larval gut. This microarray was used to monitor gene expression in early third-instar larvae of Bacillu...

  • Review
  • Open Access
18 Citations
22,599 Views
14 Pages

Tracing Monotreme Venom Evolution in the Genomics Era

  • Camilla M. Whittington and
  • Katherine Belov

2 April 2014

The monotremes (platypuses and echidnas) represent one of only four extant venomous mammalian lineages. Until recently, monotreme venom was poorly understood. However, the availability of the platypus genome and increasingly sophisticated genomic too...

  • Article
  • Open Access
18 Citations
8,060 Views
16 Pages

Extracellular Hb Enhances Cardiac Toxicity in Endotoxemic Guinea Pigs: Protective Role of Haptoglobin

  • Jin Hyen Baek,
  • Xiaoyuan Zhang,
  • Matthew C. Williams,
  • Dominik J. Schaer,
  • Paul W. Buehler and
  • Felice D'Agnillo

31 March 2014

Endotoxemia plays a major causative role in the myocardial injury and dysfunction associated with sepsis. Extracellular hemoglobin (Hb) has been shown to enhance the pathophysiology of endotoxemia. In the present study, we examined the myocardial pat...

  • Review
  • Open Access
199 Citations
17,313 Views
22 Pages

28 March 2014

Bacillus thuringiensis subsp. israelensis (Bti) is the first Bacillus thuringiensis to be found and used as an effective biological control agent against larvae of many mosquito and black fly species around the world. Its larvicidal activity resides...

  • Article
  • Open Access
22 Citations
8,441 Views
21 Pages

A qPCR Assay to Detect and Quantify Shiga Toxin-Producing E. coli (STEC) in Cattle and on Farms: A Potential Predictive Tool for STEC Culture-Positive Farms

  • Karen Verstraete,
  • Els Van Coillie,
  • Hadewig Werbrouck,
  • Stephanie Van Weyenberg,
  • Lieve Herman,
  • Jurgen Del-Favero,
  • Peter De Rijk,
  • Lieven De Zutter,
  • Maria-Adelheid Joris and
  • Marc Heyndrickx
  • + 1 author

27 March 2014

Shiga toxin-producing E. coli (STEC), of various serogroups harboring the intimin gene, form a serious threat to human health. They are asymptomatically carried by cattle. In this study, a quantitative real-time PCR (qPCR) method was developed as a m...

  • Article
  • Open Access
28 Citations
8,260 Views
14 Pages

26 March 2014

Fuel ethanol co-products known as distillers’ dried grains with solubles (DDGS) are a significant source of energy, protein, and phosphorous in animal feed. Fuel ethanol production may concentrate mycotoxins present in corn into DDGS. One hundred and...

  • Article
  • Open Access
26 Citations
7,242 Views
8 Pages

Larvicidal and Cytotoxic Potential of Squamocin on the Midgut of Aedes aegypti (Diptera: Culicidae)

  • Marilza S. Costa,
  • Jamile F. S. Cossolin,
  • Mônica J. B. Pereira,
  • Antônio E. G. Sant'Ana,
  • Milena D. Lima,
  • José C. Zanuncio and
  • José Eduardo Serrão

26 March 2014

Acetogenins are secondary metabolites exclusively produced by Annonaceae, which have antitumor, cytotoxic, and pesticide activities. In this study, we evaluated the larvicidal and cytotoxic effect of squamocin from Annona squamosa on Aedes aegypti (D...

  • Article
  • Open Access
44 Citations
8,243 Views
16 Pages

Analysis of Individual and Combined Effects of Ochratoxin A and Zearalenone on HepG2 and KK-1 Cells with Mathematical Models

  • Yuzhe Li,
  • Boyang Zhang,
  • Xiaoyun He,
  • Wen-Hsing Cheng,
  • Wentao Xu,
  • Yunbo Luo,
  • Rui Liang,
  • Haoshu Luo and
  • Kunlun Huang

26 March 2014

Ochratoxin A (OTA) and Zearalenone (ZEA) are widespread mycotoxins that contaminate foodstuffs simultaneously, but sufficient data regarding their mixed toxicities are lacking. This study aims to analyze the style of combined effects of OTA and ZEA o...

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Toxins - ISSN 2072-6651