Role of Fibre in Nutritional Management of Pancreatic Diseases

Ribichini, Emanuela; Stigliano, Serena; Rossi, Sara; Zaccari, Piera; Sacchi, Maria Carlotta; Bruno, Giovanni; Badiali, Danilo; Severi, Carola

doi:10.3390/nu11092219

Open AccessCommunication

Role of Fibre in Nutritional Management of Pancreatic Diseases

by

Emanuela Ribichini

^1,†

,

Serena Stigliano

^2,†

,

Sara Rossi

²,

Piera Zaccari

¹

,

Maria Carlotta Sacchi

¹

,

Giovanni Bruno

²

,

Danilo Badiali

²

and

Carola Severi

^2,*

¹

Department of Translational and Precision Medicine, Sapienza University of Rome, 00161 Rome, Italy

²

Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, Sapienza University of Rome, 00161 Rome, Italy

^*

Author to whom correspondence should be addressed.

^†

These two authors contribute equally to this paper.

Nutrients 2019, 11(9), 2219; https://doi.org/10.3390/nu11092219

Submission received: 19 June 2019 / Revised: 8 September 2019 / Accepted: 10 September 2019 / Published: 14 September 2019

(This article belongs to the Special Issue Dietary Fiber and Human Health)

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Abstract

The role of fibre intake in the management of patients with pancreatic disease is still controversial. In acute pancreatitis, a prebiotic enriched diet is associated with low rates of pancreatic necrosis infection, hospital stay, systemic inflammatory response syndrome and multiorgan failure. This protective effect seems to be connected with the ability of fibre to stabilise the disturbed intestinal barrier homeostasis and to reduce the infection rate. On the other hand, in patients with exocrine pancreatic insufficiency, a high content fibre diet is associated with an increased wet fecal weight and fecal fat excretion because of the fibre inhibition of pancreatic enzymes. The mechanism by which dietary fibre reduces the pancreatic enzyme activity is still not clear. It seems likely that pancreatic enzymes are absorbed on the fibre surface or entrapped in pectin, a gel-like substance, and are likely inactivated by anti-nutrient compounds present in some foods. The aim of the present review is to highlight the current knowledge on the role of fibre in the nutritional management of patients with pancreatic disorders.

Keywords: pancreatitis; pancreatic exocrine insufficiency; nutritional management; maldigestion; diet; fibre

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MDPI and ACS Style

Ribichini, E.; Stigliano, S.; Rossi, S.; Zaccari, P.; Sacchi, M.C.; Bruno, G.; Badiali, D.; Severi, C. Role of Fibre in Nutritional Management of Pancreatic Diseases. Nutrients 2019, 11, 2219. https://doi.org/10.3390/nu11092219

AMA Style

Ribichini E, Stigliano S, Rossi S, Zaccari P, Sacchi MC, Bruno G, Badiali D, Severi C. Role of Fibre in Nutritional Management of Pancreatic Diseases. Nutrients. 2019; 11(9):2219. https://doi.org/10.3390/nu11092219

Chicago/Turabian Style

Ribichini, Emanuela, Serena Stigliano, Sara Rossi, Piera Zaccari, Maria Carlotta Sacchi, Giovanni Bruno, Danilo Badiali, and Carola Severi. 2019. "Role of Fibre in Nutritional Management of Pancreatic Diseases" Nutrients 11, no. 9: 2219. https://doi.org/10.3390/nu11092219

APA Style

Ribichini, E., Stigliano, S., Rossi, S., Zaccari, P., Sacchi, M. C., Bruno, G., Badiali, D., & Severi, C. (2019). Role of Fibre in Nutritional Management of Pancreatic Diseases. Nutrients, 11(9), 2219. https://doi.org/10.3390/nu11092219

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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Role of Fibre in Nutritional Management of Pancreatic Diseases

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