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Clinics and Practice, Volume 12, Issue 6

December 2022 - 25 articles

Cover Story: From the uterine tumor spectrum, one of the most aggressive entities is leiomyosarcoma. It represents one of the great public health problems worldwide, especially from the perspective of oncological treatment. These characteristics are accentuated by the possibility of the appearance of this neoplasm as a recurrence of a smooth muscle tumor with uncertain malignant potential. Our work presents the clinical, pathological and evolutionary characteristics of these two tumor types diagnosed over a period of 5 years. The study of the p53 pathogenic pathway and the tumor inflammatory infiltrate led to the indication of a new therapeutic target. Future studies are needed to identify therapies that will determine the favorable evolution of patients diagnosed with this pathology. View this paper
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Articles (25)

  • Review
  • Open Access
8 Citations
3,817 Views
9 Pages

Colorectal Cancer Liver Metastases: Is an R1 Hepatic Resection Accepted?

  • Dimitrios Symeonidis,
  • Konstantinos Tepetes,
  • George Tzovaras,
  • Labrini Kissa,
  • Athina A. Samara,
  • Effrosyni Bompou and
  • Dimitrios Zacharoulis

19 December 2022

Metastatic colorectal cancer is associated with a rather dismal 5-year overall survival. The liver is the most commonly affected organ. Improved 5-year survival rates after successful hepatic resections for metastases confined to the liver have been...

  • Article
  • Open Access
19 Citations
4,306 Views
10 Pages

Real-Time Muscle Activity and Joint Range of Motion Monitor to Improve Shoulder Pain Rehabilitation in Wheelchair Basketball Players: A Non-Randomized Clinical Study

  • Giacomo Farì,
  • Marisa Megna,
  • Pietro Fiore,
  • Maurizio Ranieri,
  • Riccardo Marvulli,
  • Valerio Bonavolontà,
  • Francesco Paolo Bianchi,
  • Filomena Puntillo,
  • Giustino Varrassi and
  • Victor Machado Reis

16 December 2022

Wheelchair basketball (WB) involves sports gestures that expose the shoulder to high biomechanical stress and frequently lead to shoulder pain (SP). Due to their physical peculiarities and sporting performance, these athletes require specific rehabil...

  • Communication
  • Open Access
2 Citations
3,481 Views
14 Pages

VACS: VAccination disComfort Scale

  • Manolis Wallace,
  • Stavros Antonopoulos and
  • Vassilis Poulopoulos

15 December 2022

The vaccination of children is a crucial tool to protect both individuals and the world in general from various diseases and pathogens. Unfortunately, the vaccination procedure is not a pleasant one for all children, with many experiencing various le...

  • Case Report
  • Open Access
3,560 Views
9 Pages

Portal Vein Thrombosis after C-Section in a Patient with Polycythemia Vera (PV) Due to Pregnancy and Iron Deficiency Anemia (IDA)

  • Thomas Ntounis,
  • Konstantinos A. Zioutos,
  • Antonios Koutras,
  • Ioannis Prokopakis,
  • Zacharias Fasoulakis,
  • Ioakeim Sapantzoglou,
  • Paraskevas Perros,
  • Athina A. Samara,
  • Emmanouil Spanoudakis and
  • Asimina Valsamaki
  • + 8 authors

14 December 2022

Polycythemia vera (PV) is one of the three main classic disorders of Philadelphia-negative myeloproliferative neoplasms (MPNs), with the other two being essential thrombocythemia (ET) and primary myelofibrosis (PMF). PV may develop (15%) in women of...

  • Article
  • Open Access
8 Citations
2,490 Views
15 Pages

Implications of Cellular Immaturity in Necrosis and Microvascularization in Glioblastomas IDH-Wild-Type

  • Cristian Ionut Orasanu,
  • Mariana Aschie,
  • Mariana Deacu,
  • Madalina Bosoteanu,
  • Sorin Vamesu,
  • Manuela Enciu,
  • Gabriela Izabela Bălţătescu,
  • Georgeta Camelia Cozaru,
  • Anca Florentina Mitroi and
  • Raluca Ioana Voda

13 December 2022

Necrosis and increased microvascular density in glioblastoma IDH-wild-type are the consequence of both hypoxia and cellular immaturity. Our study aimed to identify the main clinical-imaging and morphogenetic risk factors associated with tumor necrosi...

  • Article
  • Open Access
5 Citations
7,879 Views
11 Pages

Accuracy of Three Types of Apex Locators versus Digital Periapical Radiography for Working Length Determination in Maxillary Premolars: An In Vitro Study

  • Masoumeh Ramezani,
  • Marjan Bolbolian,
  • Mohaddeseh Aliakbari,
  • Ahad Alizadeh,
  • Maryam Tofangchiha,
  • Seyed Mohammad Faegh,
  • Romeo Patini and
  • Giuseppe D’Amato

12 December 2022

This study aimed to compare the accuracy of three types of apex locators versus digital radiography for working length (WL) determination. This experimental study was conducted on 58 extracted maxillary premolars. The teeth were decoronated, the acce...

  • Article
  • Open Access
2 Citations
2,834 Views
9 Pages

12 December 2022

Tuberculosis (TB) remains a major global public-health problem. TB prevention and control measures are compromised by poor quality of care delivered to TB patients in health facilities during diagnosis, treatment, and follow-up; thus, this study was...

  • Case Report
  • Open Access
5 Citations
23,494 Views
14 Pages

9 December 2022

Peyronie’s disease (PD) is a fibrotic disorder of the penile tunica albuginea. To date, only a few cases of recovery from PD following medical treatment have been reported in the literature. In this article, we describe three new cases of PD wh...

  • Article
  • Open Access
17 Citations
3,868 Views
11 Pages

The Antimicrobial and Anti-Biofilm Effects of Hypericum perforatum Oil on Common Pathogens of Periodontitis: An In Vitro Study

  • Reza Bagheri,
  • Sepideh Bohlouli,
  • Solmaz Maleki Dizaj,
  • Shahriar Shahi,
  • Mohammad Yousef Memar and
  • Sara Salatin

6 December 2022

The antibacterial and anti-biofilm effects of Hypericum perforatum oil against the common pathogens of periodontitis (Escherichia coli, Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, Porphyromonas gingivalis) was investigated. Di...

  • Article
  • Open Access
3 Citations
3,050 Views
8 Pages

Estimation of Serum Calcium on the Severity and Mortality in COVID-19 Infections in Sulaymaniyah City, Kurdistan Region of Iraq: A Cross-Sectional Study

  • Jihad M. Hadi,
  • Shkar M. J. Hassan,
  • Mudhafar M. M. Saeed,
  • Bilal K. Hussein,
  • Banwan M. Ali,
  • Lava E. Muhamad,
  • Ardalan J. Abdullah,
  • Nzar N. Ali,
  • Hawre A. Rahman and
  • Hassan Q. Sofihussein
  • + 1 author

29 November 2022

Background: Coronaviruses (COV) are a large family of viruses that cause infections ranging from the common cold to more serious diseases. Mild to severe respiratory illnesses have been linked to coronavirus disease 2019 (COVID-19), which has been cl...

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Clin. Pract. - ISSN 2039-7283