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Journal of Xenobiotics, Volume 13, Issue 1

2023 March - 13 articles

Cover Story: Many modern epidemiological studies, especially from the USA, have shown a strong causal relationship between cannabis exposure and congenital anomalies (CAs). We found that European nations with high or rising cannabis use had a higher rate of orofacial CAs (FCAs) than elsewhere in that continent. Cannabis was shown to fulfill criteria for causality for orofacial clefts, anotia, congenital cataract, and holoprosencephaly at both bivariate and multivariate analysis after adjustment and also in space-time modelling. Thus, rising cannabis use is associated with many FCAs, fulfils epidemiological criteria for causality and confirms other human and animal research. The data indicate particular concerns relating to brain development and exponential genotoxic dose–responses and urges great caution with regard to community cannabinoid penetration. View this paper
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Articles (13)

  • Article
  • Open Access
18 Citations
8,080 Views
13 Pages

Ecosystem Protection through Myco-Remediation of Chromium and Arsenic

  • Neel Kamal,
  • Jagdish Parshad,
  • Baljeet Singh Saharan,
  • Monika Kayasth and ,
  • Vishal Mudgal,
  • Joginder Singh Duhan,
  • Balwan Singh Mandal and
  • Pardeep Kumar Sadh
  • + 3 authors+ 0 author

9 March 2023

The current study emphasizes fungi as an important tool against heavy metals and how isolated fungal species can be used to create a successful strategy for the bioremediation of chromium and arsenic-contaminated sites/soils. Globally, heavy metal po...

(This article belongs to the Section Ecotoxicology)
  • Brief Report
  • Open Access
2 Citations
3,468 Views
11 Pages

Nanoformulation of a Trypanocidal Drug Isometamidium Chloride Ameliorates the Apurinic-Apyrimidinic DNA Sites/Genotoxic Effects in Horse Blood Cells

  • Sandeep Singh,
  • Balvinder Kumar,
  • Neeraj Dilbaghi,
  • Nisha Devi and ,
  • Minakshi Prasad and
  • Anju Manuja
  • + 1 author+ 0 author

2 March 2023

Isometamidium chloride (ISM) is a trypanocide for the prophylactic and therapeutic use against vector-borne animal trypanosomosis (mainly Surra caused by Trypanosoma evansi) and African animal trypanosomosis caused by T. congolense/T. vivax/T. brucei...

(This article belongs to the Section Nanotoxicology and Nanopharmacology)
  • Article
  • Open Access
5 Citations
3,461 Views
16 Pages

1 March 2023

The effect of copper and nickel ions on the lipid composition of freshwater mussels Anodonta cygnea was investigated using an aquarium experiment. The contents of the main lipid classes were determined using thin layer chromatography and spectrophoto...

(This article belongs to the Section Ecotoxicology)
  • Review
  • Open Access
38 Citations
24,375 Views
11 Pages

1 March 2023

Fragrance compounds (synthetic fragrances or natural essential oils) comprise formulations of specific combinations of individual materials or mixtures. Natural or synthetic scents are core constituents of personal care and household products (PCHPs)...

(This article belongs to the Section Emerging Chemicals)
  • Article
  • Open Access
16 Citations
4,812 Views
19 Pages

Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase

  • Njogu M. Kimani,
  • Charles O. Ochieng,
  • Mike Don Ogutu,
  • Kevin Otieno Yamo and ,
  • Joab Otieno Onyango and
  • Cleydson B. R. Santos
  • + 1 author+ 0 author

21 February 2023

Compounds from Zanthoxylum chalybeum Engl. were previously reported for inhibitory activities of amylase and glucosidase enzymatic action on starch as a preliminary study toward the establishment of a management strategy against postprandial hypergly...

(This article belongs to the Section Natural Products/Herbal Medicines)
  • Article
  • Open Access
12 Citations
5,278 Views
12 Pages

Stability Study of Graphene Oxide-Bovine Serum Albumin Dispersions

  • Javier Pérez-Piñeiro,
  • Fernando Sánchez-Cea,
  • Mariana P. Arce,
  • Isabel Lado-Touriño and ,
  • María Luisa Rojas-Cervantes,
  • María Fuencisla Gilsanz,
  • Darío Gallach-Pérez,
  • Rodrigo Blasco,
  • Niurka Barrios-Bermúdez and
  • Arisbel Cerpa-Naranjo
  • + 5 authors+ 0 author

16 February 2023

In this work, a stability study of dispersions of graphene oxide and graphene oxide functionalized with polyethylene glycol (PEG) in the presence of bovine serum albumin is carried out. First, a structural characterization of these nanomaterials is p...

(This article belongs to the Section Nanotoxicology and Nanopharmacology)
  • Article
  • Open Access
25 Citations
11,351 Views
15 Pages

Phytotherapy and Drugs: Can Their Interactions Increase Side Effects in Cancer Patients?

  • Sarah Allegra,
  • Silvia De Francia,
  • Francesca Turco,
  • Ilenia Bertaggia and ,
  • Francesco Chiara,
  • Tiziana Armando,
  • Silvana Storto and
  • Maria Valentina Mussa
  • + 3 authors+ 0 author

1 February 2023

Background: The use of herbs to treat illnesses was common in all historical eras. Our aim was to describe the phytotherapeutic substances that cancer patients use most commonly, and to determine whether their use can increase side effects. Methods:...

(This article belongs to the Section Natural Products/Herbal Medicines)
  • Article
  • Open Access
7 Citations
5,514 Views
33 Pages

1 February 2023

Introduction. Since high rates of congenital anomalies (CAs), including facial CAs (FCAs), causally attributed to antenatal and community cannabis use have been reported in several recent series, it was of interest to examine this subject in detail i...

(This article belongs to the Section Natural Products/Herbal Medicines)
  • Review
  • Open Access
17 Citations
8,742 Views
13 Pages

Safety and Efficacy of Tyrosine Kinase Inhibitors in Immune Thrombocytopenic Purpura: A Systematic Review of Clinical Trials

  • Muhammad Ashar Ali,
  • Muhammad Yasir Anwar,
  • Wajeeha Aiman,
  • Gurneel Dhanesar and ,
  • Zainab Omar,
  • Mohammad Hamza,
  • Maha Zafar,
  • Harish Kumar Rengarajan and
  • Michael Maroules
  • + 4 authors+ 0 author

28 January 2023

Immune thrombocytopenic purpura (ITP) is an acquired antibody or cell-mediated platelet damage or decreased platelet production. Steroids, IV immunoglobulins (IVIG), and Rho-anti-D antibodies are the commonly used initial treatments for ITP. However,...

(This article belongs to the Section Drug Therapeutics)
  • Article
  • Open Access
9 Citations
6,279 Views
11 Pages

Assessment of the Antimalarial Treatment Failure in Ebonyi State, Southeast Nigeria

  • Chinedu Ogbonnia Egwu,
  • Chinyere Aloke,
  • Jennifer Chukwu,
  • Joshua Chidiebere Nwankwo and ,
  • Chinemerem Irem,
  • Kingsley E. Nwagu,
  • Felix Nwite,
  • Anthony Ogbonnaya Agwu,
  • Esther Alum and
  • Nwogo Ajuka Obasi
  • + 6 authors+ 1 author

3 January 2023

The fight against malaria is a continuum as the epidemic is not abating. For proper deployment of tools in the fight against malaria, an assessment of the situation is necessary. This work assessed the level of antimalarial drug treatment failure in...

(This article belongs to the Section Drug Therapeutics)
  • Article
  • Open Access
6 Citations
4,516 Views
14 Pages

21 December 2022

An analytical method for the quantitative determination of the insecticide spinetoram in cotton and soybean was established and validated using liquid chromatography tandem mass spectrometry (LC-MS/MS). Spinetoram is the mixture of two spinosyns, 3&p...

(This article belongs to the Section Ecotoxicology)
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J. Xenobiotics - ISSN 2039-4713