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Viruses, Volume 10, Issue 11

November 2018 - 84 articles

Cover Story: Potato leafroll virus (PLRV) in the Luteoviridae expresses two non-structural proteins that facilitate the cell-to-cell movement of assembled virion in plants. Using a combination of molecular virology, proteomics, and live-cell imaging, we show that these two movement proteins directly interact to traffick to the cell periphery along the outer membranes of multiple host organelles, including mitochondrial-derived vesicles and plastid stromules. Specific domains within these viral proteins direct their association with the host. View this paper.
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Articles (84)

  • Article
  • Open Access
6 Citations
4,436 Views
17 Pages

14 November 2018

The cell entry mechanism of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is not fully understood. Previous studies showed that AcMNPV entered host cells primarily through clathrin-mediated endocytosis, and could efficiently infect ce...

  • Article
  • Open Access
45 Citations
6,481 Views
17 Pages

TIM-1 Promotes Japanese Encephalitis Virus Entry and Infection

  • Jichen Niu,
  • Ya Jiang,
  • Hao Xu,
  • Changjing Zhao,
  • Guodong Zhou,
  • Puyan Chen and
  • Ruibing Cao

14 November 2018

Japanese encephalitis virus (JEV) is a mosquito-borne Flavivirus, the leading cause of viral-induced encephalitis. Several host molecules have been identified as the JEV attachment factor; however, the molecules involved in JEV entry remain poorly un...

  • Article
  • Open Access
13 Citations
5,963 Views
14 Pages

13 November 2018

We present the recently isolated virus vB_BthP-Goe4 infecting Bacillus thuringiensis HD1. Morphological investigation via transmission electron microscopy revealed key characteristics of the genus Phi29virus, but with an elongated head resulting in l...

  • Article
  • Open Access
7 Citations
3,713 Views
16 Pages

Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

  • Supachai Sakkhachornphop,
  • Sudarat Hadpech,
  • Tanchanok Wisitponchai,
  • Chansunee Panto,
  • Doungnapa Kantamala,
  • Utaiwan Utaipat,
  • Jutarat Praparattanapan,
  • Wilai Kotarathitithum,
  • Sineenart Taejaroenkul and
  • Umpa Yasamut
  • + 5 authors

13 November 2018

Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the HIV-1 capsid, AnkGAG1D4, showed a negative effect on the viral assembly of the HIV-1NL4-3 la...

  • Article
  • Open Access
40 Citations
4,598 Views
13 Pages

13 November 2018

The genus Listeria includes foodborne pathogens that cause life-threatening infections in those at risk, and sensitive and specific methods for detection of these bacteria are needed. Based on their unrivaled host specificity and ability to discrimin...

  • Review
  • Open Access
48 Citations
7,729 Views
23 Pages

Causes and Consequences of Spatial Within-Host Viral Spread

  • Molly E. Gallagher,
  • Christopher B. Brooke,
  • Ruian Ke and
  • Katia Koelle

13 November 2018

The spread of viral pathogens both between and within hosts is inherently a spatial process. While the spatial aspects of viral spread at the epidemiological level have been increasingly well characterized, the spatial aspects of viral spread within...

  • Article
  • Open Access
12 Citations
4,144 Views
13 Pages

13 November 2018

Hymenoscyphus albidus is a native fungus in Europe where it behaves as a harmless decomposer of leaves of common ash. Its close relative Hymenoscyphus fraxineus was introduced into Europe from Asia and currently threatens ash (Fraxinus sp.) stands al...

  • Review
  • Open Access
39 Citations
11,184 Views
18 Pages

ISG15, a Small Molecule with Huge Implications: Regulation of Mitochondrial Homeostasis

  • Manuel Albert,
  • Martina Bécares,
  • Michela Falqui,
  • Carlos Fernández-Lozano and
  • Susana Guerra

13 November 2018

Viruses are responsible for the majority of infectious diseases, from the common cold to HIV/AIDS or hemorrhagic fevers, the latter with devastating effects on the human population. Accordingly, the development of efficient antiviral therapies is a m...

  • Article
  • Open Access
30 Citations
5,219 Views
17 Pages

Antibiotic Therapy Using Phage Depolymerases: Robustness Across a Range of Conditions

  • Han Lin,
  • Matthew L. Paff,
  • Ian J. Molineux and
  • James J. Bull

12 November 2018

Phage-derived depolymerases directed against bacterial capsules are showing therapeutic promise in various animal models of infection. However, individual animal model studies are often constrained by use of highly specific protocols, such that resul...

  • Article
  • Open Access
23 Citations
4,840 Views
17 Pages

Following in the Footsteps of the Chikungunya Virus in Brazil: The First Autochthonous Cases in Amapá in 2014 and Its Emergence in Rio de Janeiro during 2016

  • Thiara Manuele Alves De Souza,
  • Edcelha D’Athaide Ribeiro,
  • Valmir Corrêa e Corrêa,
  • Paulo Vieira Damasco,
  • Carla Cunha Santos,
  • Fernanda De Bruycker-Nogueira,
  • Thaís Chouin-Carneiro,
  • Nieli Rodrigues da Costa Faria,
  • Priscila Conrado Guerra Nunes and
  • Manoela Heringer
  • + 6 authors

12 November 2018

Currently, Brazil lives a triple arboviruses epidemic (DENV, ZIKV and CHIKV) making the differential diagnosis difficult for health professionals. Here, we aimed to investigate chikungunya cases and the possible occurrence of co-infections during the...

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Viruses - ISSN 1999-4915