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Current Oncology, Volume 31, Issue 7

July 2024 - 43 articles

Cover Story: Chimeric antigen receptor (CAR) T-cell therapy has revolutionised the treatment landscape for patients with multiple myeloma and is likely to be approved in Canada soon. Idecabtagene vicleucel (Ide-cel) (ABECMA®) and Ciltacabtagene autoleucel (Cilta-cel) (CARVYKTI®) are the two CAR T-cell therapy products for patients with relapsed or refractory multiple myeloma commercially available in the US and Europe. Although they have shown unprecedented efficacy, their clinical and logistical limitations must also be acknowledged. Therefore, it is timely that we review the latest evidence on CAR T-cell therapy in multiple myeloma, with a focus on its relevance and impact in the Canadian setting. View this paper
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Articles (43)

  • Case Report
  • Open Access
2 Citations
2,213 Views
7 Pages

14 July 2024

A 48-year-old woman without obvious environmental risk factors was diagnosed with metastatic urothelial carcinoma harboring a mutation in EGFR typical of driver mutations for non-small cell lung cancer. Within a year, her cancer progressed on four st...

  • Opinion
  • Open Access
11 Citations
4,968 Views
12 Pages

12 July 2024

Resilience is defined as the maintenance or relatively quick recovery of mental health during and after adversity. Rather than focusing on psychopathology and its causes, resilience research aims to understand what protective mechanisms shield indivi...

  • Review
  • Open Access
69 Citations
22,604 Views
9 Pages

Temozolomide (TMZ) in the Treatment of Glioblastoma Multiforme—A Literature Review and Clinical Outcomes

  • Marcin Jezierzański,
  • Natalia Nafalska,
  • Małgorzata Stopyra,
  • Tomasz Furgoł,
  • Michał Miciak,
  • Jacek Kabut and
  • Iwona Gisterek-Grocholska

12 July 2024

Glioblastoma multiforme (GBM) is one of the most aggressive primary tumors of the central nervous system. It is associated with a very poor prognosis, with up to half of patients failing to survive the first year after diagnosis. It develops from gli...

  • Communication
  • Open Access
2,428 Views
9 Pages

Is Spirometry a Sufficient Test for Assessing Respiratory Function after Lung Resection?

  • Damian Wnuk,
  • Tomasz Marjański,
  • Bartłomiej Tomasik,
  • Joanna Żuralska-Wnuk and
  • Witold Rzyman

11 July 2024

Background: The prediction of postoperative functional status in non-small cell lung cancer patients based on preoperative assessment of physical and respiratory capacity is inadequate based on recent RCTs. Material and methods: Prospectively collect...

  • Case Report
  • Open Access
1 Citations
2,195 Views
7 Pages

Total Iliocaval Reconstruction in a Complex Palliative Patient with Malignant Inferior Vena Cava Syndrome

  • Jack Lofroth,
  • Amir Pourghadiri,
  • Anastasia Hadjivassiliou,
  • Manraj Heran,
  • Gerald Legiehn,
  • Stephen Ho and
  • Ravjot Dhatt

9 July 2024

Inferior vena cava (IVC) compression secondary to mass effect is accompanied by edema, ascites, back and abdominal pain, and central nervous system symptoms. Most IVC syndrome cases described in the literature focus on the focal treatment of IVC lesi...

  • Case Report
  • Open Access
1 Citations
3,561 Views
10 Pages

Radiosurgically Treated Recurrent Cerebellar Hemangioblastoma: A Case Report and Literature Review

  • François Fabi,
  • Ève Chamberland,
  • Myreille D’Astous,
  • Karine Michaud,
  • Martin Côté and
  • Isabelle Thibault

9 July 2024

Background: Cystic, sporadic hemangioblastomas (HBLs) represent a unique, therapeutically challenging subset of central nervous system tumors, mainly due to their unpredictable growth patterns and potential for symptomatic progression. This study aim...

  • Review
  • Open Access
2 Citations
7,688 Views
19 Pages

6 July 2024

Multiple myeloma (MM) is an incurable plasma cell malignancy. In the context of the current standard of care therapies in Canada, outcomes among patients with relapsed/refractory multiple myeloma (RRMM), particularly those with triple-class (or more)...

  • Article
  • Open Access
1 Citations
3,642 Views
10 Pages

6 July 2024

(1) Purpose: The purpose of this study was to describe the outcomes of diagnostic breast imaging and the incidence of delayed breast cancer diagnosis in the study population. (2) Methods: We collected the outcome data from diagnostic mammograms and/o...

  • Review
  • Open Access
9 Citations
9,111 Views
16 Pages

Endoscopic Grading and Sampling of Gastric Precancerous Lesions: A Comprehensive Literature Review

  • Georgios Tziatzios,
  • Dimitrios Ι. Ziogas,
  • Paraskevas Gkolfakis,
  • Vasilios Papadopoulos,
  • Apostolis Papaefthymiou,
  • Nikoletta Mathou,
  • Athanasios Giannakopoulos,
  • Gerasimos Gerasimatos,
  • Konstantina D. Paraskeva and
  • Konstantinos Triantafyllou

5 July 2024

Gastric cancer remains a disease with an ominous prognosis, while early gastric cancer has a good-to-excellent prognosis, with 5-year survival rates of up to 92.6% after successful endoscopic resection. In this context, the accurate identification of...

  • Review
  • Open Access
2,106 Views
15 Pages

Cancer Prevention and Cultural Continuity for Métis Peoples in Canada: A Scoping Review

  • Maria Diaz Vega,
  • José Diego Marques Santos,
  • Stephanie Witham,
  • Marg Friesen,
  • Tegan Brock,
  • Sheila Laroque,
  • Jennifer Sedgewick,
  • Tracey Carr and
  • Gary Groot

5 July 2024

The purpose of this scoping review was to map the literature on the relationship between cultural continuity and health among Métis people as well as how this knowledge could be translated into cancer prevention initiatives. We included any M&...

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Curr. Oncol. - ISSN 1718-7729