Current Oncology, Volume 25, Issue 2

The paper “Connecting people with cancer to physical activity and exercise programs: a pathway to create accessibility and engagement” is very timely. [...]

Background: Clinical trials are vital for evidence-based cancer care. Oncologist engagement in clinical trials has an effect on patient recruitment, which in turn can affect trial success. Identifying barriers to clinical trial participation might en...

Background: Overuse of surveillance imaging in patients after curative treatment for early breast cancer (EBC) was recently identified as one of the Choosing Wisely Canada initiatives to improve the quality of cancer care. We undertook a population-l...

Purpose: The mainstay of treatment for ductal carcinoma in situ (DCIS) involves surgery in the form of mastectomy or lumpectomy. Inconsistency in the use of endocrine therapy (ET) for DCIS is evident worldwide. We sought to assess the variation in ET...

This article reviews intravenous vitamin C (IV C) in cancer care and offers a rational approach to enable medical oncologists and integrative practitioners to safely provide IV C combined with oral vitamin C to patients. The use of IV C is a safe sup...

Recent guidelines concerning exercise for people with cancer provide evidence-based direction for exercise assessment and prescription for clinicians and their patients. Although the guidelines promote exercise integration into clinical care for peop...

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIS) are recommended as first-line systemic therapy for patients with non-small-cell lung cancer (NSCLC) having mutations in the EGFR gene. Resistance to TKIS eventually occurs in a...

Three groups of men are at high risk of developing prostate cancer: men with a strong family history of prostate cancer, men of West African or Caribbean ancestry, and men with a germline pathogenic variant in a prostate cancer–associated gene. Despi...

Patient-reported outcomes measures (PROMS) are an important component of the shift from disease-centred to person-centred care. In oncology, PROMS describe the effects of cancer and its treatment from the patient perspective and ideally enable patien...

Background: The neutrophil–lymphocyte ratio (NLR) has been reported to correlate with patient outcome in several cancers, including breast cancer. We evaluated whether the NLR can be a predictive factor for pathologic complete response (PCR) after ne...

Background: The actual practices of routine follow-up after curative treatment for head-and-neck cancer are unknown, and existing guidelines are not evidence-based. Methods: This retrospective population-based study used administrative data to descri...

Background: We aimed to develop a new EGFR mutation–predictive scoring system to use in screening for EGFR-mutated lung adenocarcinomas (LACS). Methods: The study enrolled 279 patients with LAC, including 121 patients with EGFR wild-type tumours and...

Background: A twice-weekly galactomannan (GM) screening protocol was implemented in high-risk hematology inpatients. Study objectives were to determine adherence to the protocol, use of selected resources, and patient outcomes. Methods: This retrospe...

Background: Radiation therapy (RT) after mastectomy for breast cancer can improve survival outcomes, but has been associated with inferior cosmesis after breast reconstruction. In the literature, RT dose and fractionation schedules are inconsistently...

Background: Our objective was to determine whether, compared with control interventions, pharmacologic interventions reduce the severity of fatigue in patients with cancer or recipients of hematopoietic stem-cell transplantation (HSCT). Methods: For...

Approximately 11% of patients with breast cancer (BCA) are diagnosed before menopause, and because in most of those patients the tumour expresses a hormone receptor, treatment with endocrine interventions can be applied in any setting of disease (ear...

Background: Despite the fact that heterozygosity for a pathogenic ATM variant is present in 1%–2% of the adult population, clinical guidelines to inform physicians and genetic counsellors about optimal management in that population are lacking. Metho...

Time is important now. Time was, for a long time, only abstractly relevant—usually in the quiet moments following a holiday, or birthday, or funeral[...]

Ductal carcinoma in situ (dcis) is presumably not a metastatic disease [...]