2014 August - 21 articles
Early in clinical training, medical oncologists are taught that the goals of any palliative oncologic therapy include symptom control, quality-of-life improvement through disease stabilization, and prolongation of progression-free survival.[...]
In 2007, the U.S. Institute of Medicine delivered a report titled Cancer Care for the Whole Patient: Meeting Psychosocial Health Needs1, in which gaps in the provision of psychosocial care for cancer patients were identified.[...]
As elegantly reported by Drs. Shea–Budgell, Donnellan, and colleagues in the last issue of Current Oncology, venous thromboembolism (VTE) is a frequent clinical problem in cancer patients1,2.[...]
(1) Background: Now more than ever, cancer patients want health information. Little has been published to characterize the information needs and preferred sources of that information for patients who have completed cancer treatment. (2) Methods: We u...
(1) Purpose: In the present study, we aimed to investigate the effects of chemotherapy-induced peripheral neurotoxicity (cipn) on psychological distress and sleep quality in cancer patients. (2) Methods: A total of 706 cancer patients were interviewe...
(1) Background: Adjuvant chemotherapy started more than 56 days after colon cancer resection has been associated with lesser overall survival among patients with stage iii colon cancer. The objective of the present population-based study was to deter...
Background: Hospitalized patients with advanced cancer often have a poor performance status, which is considered a relative contraindication to cytotoxic chemotherapy. We investigated outcomes in hospitalized solid tumour oncology patients who receiv...
Evidence-based treatment guidelines exist to improve quality of care for patients and are based on randomized trials that show evidence of benefit.[...]
As I reflect on my almost two decades in politics, I am proud of the accomplishments of the governments I was part of....[...]
(1) Purpose: Research suggests that physicians neglect preventive care for cancer survivors. A survivor’s self-motivation with respect to preventive care is unknown. Using protective skin care as a proxy, our aims were to characterize preventive care...
Background: Combinations of chemotherapy regimens and monoclonal antibodies have been demonstrated to improve clinical outcomes in patients with metastatic colorectal cancer (MCRC). Although these combination treatment strategies are safe and effecti...
(1) Introduction: We set out to evaluate the prognostic value of 18F-fluorodeoxyglucose positron-emission tomography (pet) in patients with advanced (non-transplant-eligible) hepatocellular carcinoma (hcc) and to evaluate the correlation between stan...
(1) Background: Almost 40% of people diagnosed with colorectal cancer will die from their disease, most with metastatic spread. When feasible, hepatic resection offers the greatest probability of cure for isolated liver metastases, but there are barr...
(1) Background: Impact factor (if) is often used as a measure of journal quality. The purpose of the present study was to determine whether trials with positive outcomes are more likely to be published in journals with higher ifs. (2) Methods: We rev...
We conducted a systematic review to determine the appropriate use of bortezomib alone or in combination with other agents in patients with multiple myeloma (MM). We searched MEDLINE, EMBASE, the Cochrane Library, conference proceedings, and the refer...
Background: Chemotherapy is an effective treatment in the fight against many cancers. Medication errors in oncology can be particularly serious given the narrow therapeutic window of antineoplastic drugs and their high toxicities. Computerized prescr...
Introduction: We conducted a systematic review to determine the optimal treatment options in patients with desmoid tumours who have declined observational management. Methods: A search was conducted of the medline and embase databases (1990 to Septem...
(1) Background: Although antineoplastic agents are critical in the treatment of cancer, they can potentially cause hypersensitivity reactions that can have serious consequences. When such a reaction occurs, clinicians can either continue the treatmen...
Objectives: We set out to determine the optimal treatment options—surgery, radiation therapy (RT), systemic therapy, or any combinations thereof—for patients with desmoid tumours once the decision to undergo active treatment has been made (that is, m...
Pancreatic cancer is the 4th leading cause of cancerrelated death. Complete surgical resection (CR0) is considered the only curative treatment. Most patients present with unresectable or borderline resectable disease. Many small phase i/ii trials hav...
In an 11-year-old boy with osteosarcoma in the proximal tibia (type iii), 2 cycles of dia chemotherapy (cisplatin, ifosfamide, doxorubicin) were administered preoperatively while epiphysiolysis was performed. Clinical response was determined to be co...
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