Next Article in Journal
Screening Mammography: The Turning of the Tide?
Previous Article in Journal
Role of Neoadjuvant Therapy in the Management of Pancreatic Cancer: Is the Era of Biomarker-Directed Therapy Here?
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Current Oncology
Volume 21
Issue 4
10.3747/co.21.1956
curroncol-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis

by
S.F. Xu
1,*,
X.C. Yu
1,
M. Xu
1 and
X. Chen
2
1
Orthopaedic Department, General Hospital of Jinan Military Region, Jinan, China
2
Department of Orthopaedic Surgery, Tangdu Hospital, Xi’an, China
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2014, 21(4), 658-662; https://doi.org/10.3747/co.21.1956
Submission received: 8 May 2014 / Revised: 9 June 2014 / Accepted: 6 July 2014 / Published: 1 August 2014

Abstract

In an 11-year-old boy with osteosarcoma in the proximal tibia (type iii), 2 cycles of dia chemotherapy (cisplatin, ifosfamide, doxorubicin) were administered preoperatively while epiphysiolysis was performed. Clinical response was determined to be complete by radiography and histopathology. Marginal excision was then performed with preservation of the proximal tibial epiphysis. Metaphyseal reconstruction was performed using distraction osteogenesis. Six cycles of dia chemotherapy were administered postoperatively. Twenty months later, the patient had developed no complications and experienced full bone healing, with no limb discrepancy. In selected adolescent patients with osteosarcoma, in whom the tumour is in full contact with the epiphysis, epiphyseal preservation by epiphysiolysis and reconstruction by distraction osteogenesis can provide an excellent outcome, resulting in a stable reconstruction that functionally restores the native limb.
Keywords: osteosarcoma; epiphysis preservation; epiphysiolysis; distraction osteogenesis; limb function; quality of life osteosarcoma; epiphysis preservation; epiphysiolysis; distraction osteogenesis; limb function; quality of life

Share and Cite

MDPI and ACS Style

Xu, S.F.; Yu, X.C.; Xu, M.; Chen, X. Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis. Curr. Oncol. 2014, 21, 658-662. https://doi.org/10.3747/co.21.1956

AMA Style

Xu SF, Yu XC, Xu M, Chen X. Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis. Current Oncology. 2014; 21(4):658-662. https://doi.org/10.3747/co.21.1956

Chicago/Turabian Style

Xu, S.F., X.C. Yu, M. Xu, and X. Chen. 2014. "Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis" Current Oncology 21, no. 4: 658-662. https://doi.org/10.3747/co.21.1956

APA Style

Xu, S. F., Yu, X. C., Xu, M., & Chen, X. (2014). Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis. Current Oncology, 21(4), 658-662. https://doi.org/10.3747/co.21.1956

Article Metrics

Back to TopTop