June 2012 - 21 articles
Purpose: Intermittent androgen deprivation is increasingly used as an alternative to continuous life-long androgen deprivation therapy for men with advanced or recurrent prostate cancer. Recent Findings: Two recent phase III trials have clarified the...
Since the year 2000, tremendous progress has been made in the understanding of castration-resistant prostate cancer (CRPC), a disease state now recognized to retain androgen receptor (AR)—dependency in most cases. That understanding led to the ration...
Treatment options for castration-resistant prostate cancer (CRPC) have evolved since the start of the 2000s, with most of the new effective therapies appearing since 2010. In 2004, docetaxel was the first chemotherapeutic agent to improve survival in...
The number of prostate cancer survivors is rapidly growing in the Western world. As a result of better oncologic outcomes, more patients are living longer with the adverse effects of treatment, which can be both functional and psychological. Clinicia...
It was with a great deal of pride that I accepted to be the guest editor of this Current Oncology supplement dedicated to prostate cancer. It is especially exciting to realize that the whole supplement was able to be based on data that has only recen...
Prostate cancer is a common malignancy worldwide, and in Canada, it is the most frequently diagnosed cancer in men. The stratification of prostate cancer into risk categories has allowed for improved counselling of patients and provides guidance for...
Objective: Many scientific studies have shown that Asparagus officinalis has an antitumour effect and enhances human immunity, but the active components and the antitumour mechanisms are unclear. We investigated the effects of saponins isolated from...
Background: Patients with malignant ascites (MA) usually experience poor quality of life, and treatment of this symptom remains a challenge. Oxidative stress, which can cause oxidative damage to DNA, plays a pivotal role in carcinogenesis; however, t...
Background and Objectives: The present study evaluated the potential role of lysophosphatidic acid receptors (LPARS) in processes leading to local invasiveness and metastasis in Chinese pancreatic carcinoma. Methods: Real-time reverse-transcriptase p...
PE vte Objective: We aimed to determine which combination of physical examination (PE), mammography (MAM), and ultrasonography (US) would optimize breast cancer detection in China. Methods: We conducted a trial of screening with pe, mam, and us among...
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