May 2009 - 11 articles
The purpose of screening is to identify preclinical and asymptomatic cases of a disease in a population at risk—as opposed to making a diagnosis based on a patient’s presentation with symptoms and disease. [...]
Background: A recent report suggested that women who had been taking hormone replacement therapy (hrt) experienced significantly decreased survival after a lung cancer diagnosis. Given the large cohort of women who have received hrt, it is important...
Objective: We proposed to document the effect of arm morbidity and disability in 40 Canadian women who were 12–24 months post breast cancer surgery. Methods: We completed 40 qualitative interviews as one component of a multidisciplinary national long...
Malignant melanoma of the skin is the most frequent cause of mortality in skin cancer. Despite various efforts toward increased early detection and prevention of melanoma, approximately 20% of patients will die because of disseminated metastases. [...]
Objective: We compared the efficacy of a story-based writing style with that of a fact-based writing style for educational material on brain metastases. Methods: Identical informational content on four topics—radiation therapy, side effects, steroid...
Many modern radiotherapy centers now have image-guided intensity-modulated radiotherapy (ig-imrt) tools available for clinical use, and the technique offers many options for patients requiring palliative radiotherapy. We describe a single-institution...
Exosomes are nanometre-size vesicles manufactured within late multi-vesicular endosomes and actively secreted into the extracellular environment [...]
A greater understanding of the factors and pathways controlling angiogenesis in tumours has allowed the development of a number of agents that selectively inhibit the pathways mediating that activity. The results to date of clinical trials with such...
The standard treatment for locally advanced urothelial bladder carcinoma is radical cystectomy or chemoradiation. Sarcomatoid urothelial carcinoma, a rare tumour, is treated with radical cystectomy because the response to radiation therapy alone is p...
We read the interesting pilot study of Dr. Nayot and colleagues on the use of preoperative 18F-fluorodeoxyglucose positron emission tomography (fdg-pet) with computed tomography (ct) scanning to detect metastatic nodes in subjects with endometrial [....
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