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Current Oncology
Volume 16
Issue 3
10.3747/co.v16i3.396
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Article

High-Grade Hyperinvasive Sarcomatoid Urothelial Bladder Carcinoma Demonstrating Complete Response to Bladder-Preserving Chemoradiation

by
Jonathan B. Wallach
*,
B. Wang
and
N. Sanfilippo
New York University Medical Center, New York, NY 10016, USA
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2009, 16(3), 55-57; https://doi.org/10.3747/co.v16i3.396
Submission received: 5 February 2009 / Revised: 4 March 2009 / Accepted: 2 April 2009 / Published: 1 May 2009

Abstract

The standard treatment for locally advanced urothelial bladder carcinoma is radical cystectomy or chemoradiation. Sarcomatoid urothelial carcinoma, a rare tumour, is treated with radical cystectomy because the response to radiation therapy alone is poor in other sarcomas. We report a case of high-grade hyperinvasive urothelial bladder carcinoma with sarcomatoid differentiation. The patient refused cystectomy, and so a chemoradiation regimen was devised for her treatment. She completed the regimen and has since demonstrated a complete response to chemoradiation therapy clinically and pathologically by biopsy. The patient has therefore been able to attain a complete response while preserving a functional bladder.
Keywords: bladder carcinoma; sarcomatoid carcinoma; chemotherapy; radiation oncology; cystectomy; quality of life; bladder preservation bladder carcinoma; sarcomatoid carcinoma; chemotherapy; radiation oncology; cystectomy; quality of life; bladder preservation

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MDPI and ACS Style

Wallach, J.B.; Wang, B.; Sanfilippo, N. High-Grade Hyperinvasive Sarcomatoid Urothelial Bladder Carcinoma Demonstrating Complete Response to Bladder-Preserving Chemoradiation. Curr. Oncol. 2009, 16, 55-57. https://doi.org/10.3747/co.v16i3.396

AMA Style

Wallach JB, Wang B, Sanfilippo N. High-Grade Hyperinvasive Sarcomatoid Urothelial Bladder Carcinoma Demonstrating Complete Response to Bladder-Preserving Chemoradiation. Current Oncology. 2009; 16(3):55-57. https://doi.org/10.3747/co.v16i3.396

Chicago/Turabian Style

Wallach, Jonathan B., B. Wang, and N. Sanfilippo. 2009. "High-Grade Hyperinvasive Sarcomatoid Urothelial Bladder Carcinoma Demonstrating Complete Response to Bladder-Preserving Chemoradiation" Current Oncology 16, no. 3: 55-57. https://doi.org/10.3747/co.v16i3.396

APA Style

Wallach, J. B., Wang, B., & Sanfilippo, N. (2009). High-Grade Hyperinvasive Sarcomatoid Urothelial Bladder Carcinoma Demonstrating Complete Response to Bladder-Preserving Chemoradiation. Current Oncology, 16(3), 55-57. https://doi.org/10.3747/co.v16i3.396

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