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Mar. Drugs, Volume 3, Issue 1 (March 2005) – 3 articles , Pages 1-21

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Article
Cytotoxicity and Inhibition of Lymphocyte Proliferation of Fasciculatin, a Linear Furanosesterterpene Isolated from Ircinia variabilis Collected from the Atlantic Coast of Morocco
by Saida Rifai, Aziz Fassouane, Paulo M. Pinho, Anake Kijjoa, Nair Nazareth, Maria São José Nascimento and Werner Herz
Mar. Drugs 2005, 3(1), 15-21; https://doi.org/10.3390/md301015 - 15 Mar 2005
Cited by 19 | Viewed by 10506
Abstract
Fasciculatin, a furanosesterterpene isolated from the marine sponge Ircinia variabilis from the Atlantic Coast of Morocco, has been evaluated for its influence on a mitogen-induced proliferation of human lymphocytes and growth of human tumor cell lines. Full article
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Article
Marine Sponge Dysidea herbacea revisited: Another Brominated Diphenyl Ether
by Madhavi S. Agrawal and Bruce F. Bowden
Mar. Drugs 2005, 3(1), 9-14; https://doi.org/10.3390/md301009 - 14 Mar 2005
Cited by 17 | Viewed by 9902
Abstract
A pentabrominated phenolic diphenyl ether (1) that has not previously been reported from marine sources has been isolated from Dysidea herbacea collected at Pelorus Island, Great Barrier Reef, Australia. The structure was determined by comparison of NMR data with those of known structurally-related [...] Read more.
A pentabrominated phenolic diphenyl ether (1) that has not previously been reported from marine sources has been isolated from Dysidea herbacea collected at Pelorus Island, Great Barrier Reef, Australia. The structure was determined by comparison of NMR data with those of known structurally-related metabolites. NMR spectral assignments for (1) are discussed in context with those of three previously reported isomeric pentabrominated phenolic diphenyl ethers. Full article
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Article
Amphidinolides B4 and B5, Potent Cytotoxic 26-Membered Macrolides from Dinoflagellate Amphidinium Species
by Masashi Tsuda, Yuuko Kariya, Rie Iwamoto, Eri Fukushi, Jun Kawabata and Jun’ichi Kobayashi
Mar. Drugs 2005, 3(1), 1-8; https://doi.org/10.3390/md301001 - 1 Mar 2005
Cited by 24 | Viewed by 8322
Abstract
Two new cytotoxic 26-membered macrolides, amphidinolides B4 (1) and B5 (2), have been isolated from a marine dinoflagellate Amphidinium sp. (strain Y-100), and the structures were elucidated on the basis of detailed analyses of 2D NMR data including 13C−13C correlations. Full article
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