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Marine Drugs, Volume 19, Issue 9

September 2021 - 55 articles

Cover Story: Seaweeds contain unique bioactive metabolites that are not found in terrestrial plants because of the harsh environment in which they survive, leading to in vitro and in vivo studies of their prevention and treatment effects. This review summarizes studies that focused on the beneficial effects of seaweeds and their natural products targeting markers involved in a cascade of mechanisms related to CVD pathogenesis. The purpose of this review is to describe the potential of seaweeds and their natural products for preventing and treating CVD based on in vivo and in vitro studies. View this paper.
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Articles (55)

  • Article
  • Open Access
14 Citations
4,222 Views
17 Pages

RSK1 vs. RSK2 Inhibitory Activity of the Marine β-Carboline Alkaloid Manzamine A: A Biochemical, Cervical Cancer Protein Expression, and Computational Study

  • Alejandro M. S. Mayer,
  • Mary L. Hall,
  • Joseph Lach,
  • Jonathan Clifford,
  • Kevin Chandrasena,
  • Caitlin Canton,
  • Maria Kontoyianni,
  • Yeun-Mun Choo,
  • Dev Karan and
  • Mark T. Hamann

7 September 2021

Manzamines are complex polycyclic marine-derived β-carboline alkaloids with reported anticancer, immunostimulatory, anti-inflammatory, antibacterial, antiviral, antimalarial, neuritogenic, hyperlipidemia, and atherosclerosis suppression bioactivities...

  • Article
  • Open Access
3 Citations
3,305 Views
12 Pages

Structure of the 4-O-[1-Carboxyethyl]-d-Mannose-Containing O-Specific Polysaccharide of a Halophilic Bacterium Salinivibrio sp. EG9S8QL

  • Elena N. Sigida,
  • Ibrahim M. Ibrahim,
  • Maxim S. Kokoulin,
  • Hussein H. Abulreesh,
  • Khaled Elbanna,
  • Svetlana A. Konnova and
  • Yulia P. Fedonenko

7 September 2021

The moderately halophilic strain Salinivibrio sp. EG9S8QL was isolated among 11 halophilic strains from saline mud (Emisal Salt Company, Lake Qarun, Fayoum, Egypt). The lipopolysaccharide was extracted from dried cells of Salinivibrio sp. EG9S8QL by...

  • Article
  • Open Access
16 Citations
3,233 Views
10 Pages

6 September 2021

The fungal strain, Fusarium sp. LY019, was obtained from the Red Sea sponge Suberea mollis. Bioassay-directed partition of the antimicrobial fraction of the extract of the culture of the fungus provided two dimeric alkaloids, fusaripyridines A and B...

  • Article
  • Open Access
9 Citations
3,211 Views
20 Pages

4 September 2021

Five native Sargassaceae species from Brittany (France) living in rockpools were surveyed over time to investigate photoprotective strategies according to their tidal position. We gave evidences for the existence of a species distribution between poo...

  • Review
  • Open Access
24 Citations
5,868 Views
25 Pages

Methods in Microbial Biodiscovery

  • Angela A. Salim,
  • Zeinab G. Khalil,
  • Ahmed H. Elbanna,
  • Taizong Wu and
  • Robert J. Capon

3 September 2021

This review presents an account of the microbial biodiscovery methodology developed and applied in our laboratory at The University of Queensland, Institute for Molecular Bioscience, with examples drawn from our experiences studying natural products...

  • Article
  • Open Access
8 Citations
6,823 Views
17 Pages

Changes in the Molecular Characteristics of Bovine and Marine Collagen in the Presence of Proteolytic Enzymes as a Stage Used in Scaffold Formation

  • Marfa N. Egorikhina,
  • Ludmila L. Semenycheva,
  • Victoria O. Chasova,
  • Irina I. Bronnikova,
  • Yulia P. Rubtsova,
  • Evgeniy A. Zakharychev and
  • Diana Ya. Aleynik

2 September 2021

Biopolymers, in particular collagen and fibrinogen, are the leading materials for use in tissue engineering. When developing technology for scaffold formation, it is important to understand the properties of the source materials as well as the mechan...

  • Review
  • Open Access
31 Citations
5,404 Views
12 Pages

1 September 2021

Metabolic syndrome, a cluster of metabolic disorders including central obesity, insulin resistance, hyperglycemia, dyslipidemia, and hypertension, has become a major public health problem worldwide. It is of great significance to develop natural prod...

  • Article
  • Open Access
16 Citations
3,975 Views
10 Pages

Sargachromenol Purified from Sargassum horneri Inhibits Inflammatory Responses via Activation of Nrf2/HO-1 Signaling in LPS-Stimulated Macrophages

  • Eui-Jeong Han,
  • Thilina U. Jayawardena,
  • Jae-Hyuk Jang,
  • Ilekuttige Priyan Shanura Fernando,
  • Youngheun Jee,
  • You-Jin Jeon,
  • Dae-Sung Lee,
  • Jeong-Min Lee,
  • Mi-Jin Yim and
  • Lei Wang
  • + 2 authors

31 August 2021

In this study, we isolated sargachromenol (SC) from Sargassum horneri and evaluated its anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. SC did not show cytotoxicity at all concentrations and effectively increase...

  • Article
  • Open Access
28 Citations
5,527 Views
25 Pages

Biochemical Characterization of Cassiopea andromeda (Forsskål, 1775), Another Red Sea Jellyfish in the Western Mediterranean Sea

  • Gianluca De Rinaldis,
  • Antonella Leone,
  • Stefania De Domenico,
  • Mar Bosch-Belmar,
  • Rasa Slizyte,
  • Giacomo Milisenda,
  • Annalisa Santucci,
  • Clara Albano and
  • Stefano Piraino

31 August 2021

Increasing frequency of native jellyfish proliferations and massive appearance of non-indigenous jellyfish species recently concur to impact Mediterranean coastal ecosystems and human activities at sea. Nonetheless, jellyfish biomass may represent an...

  • Article
  • Open Access
4 Citations
3,483 Views
15 Pages

31 August 2021

Prevention of acute kidney injury caused by drugs is still a clinical problem to be solved urgently. Astaxanthin (AST) and docosahexaenoic acid (DHA) are important marine-derived active ingredients, and they are reported to exhibit renal protective a...

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Mar. Drugs - ISSN 1660-3397