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Marine Drugs, Volume 10, Issue 8

August 2012 - 15 articles

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Articles (15)

  • Article
  • Open Access
35 Citations
12,599 Views
15 Pages

10 August 2012

Fucosylated chondroitin sulfate (FuCS), a kind of complex glycosaminoglycan from sea cucumber, has potent anticoagulant activity. In order to understand the relationship between structures and activity, the depolymerized FuCS (dFuCS) was chosen to pr...

  • Article
  • Open Access
7 Citations
7,492 Views
9 Pages

Briareolate Esters from the Gorgonian Briareum asbestinum

  • Rian J. Meginley,
  • Prasoon Gupta,
  • Thomas C. Schulz,
  • Amanda B. McLean,
  • Allan J. Robins and
  • Lyndon M. West

10 August 2012

Two new briarane diterpenoids briareolate esters J (1) and K (2) were isolated from the methanolic extract of the octocoral Briareum asbestinum collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by int...

  • Review
  • Open Access
53 Citations
10,661 Views
40 Pages

Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities and Biological Roles

  • Vladimir I. Kalinin,
  • Natalia V. Ivanchina,
  • Vladimir B. Krasokhin,
  • Tatyana N. Makarieva and
  • Valentin A. Stonik

10 August 2012

Literature data about glycosides from sponges (Porifera, Demospongiae) are reviewed. Structural diversity, biological activities, taxonomic distribution and biological functions of these natural products are discussed.

  • Article
  • Open Access
51 Citations
9,424 Views
16 Pages

Trypanocidal Action of (−)-Elatol Involves an Oxidative Stress Triggered by Mitochondria Dysfunction

  • Vânia Cristina Desoti,
  • Danielle Lazarin-Bidóia,
  • Daniela Bueno Sudatti,
  • Renato Crespo Pereira,
  • Antonio Alonso,
  • Tania Ueda-Nakamura,
  • Benedito Prado Dias Filho,
  • Celso Vataru Nakamura and
  • Sueli De Oliveira Silva

3 August 2012

Natural compounds have shown good potential for the discovery of new chemotherapeutics for the treatment of Chagas’ disease. Recently, our group reported the effective trypanocidal activity of (−)-elatol, extracted from the red macroalgae Laurencia d...

  • Article
  • Open Access
25 Citations
7,457 Views
12 Pages

A Great Barrier Reef Sinularia sp. Yields Two New Cytotoxic Diterpenes

  • Anthony D. Wright,
  • Jonathan L. Nielson,
  • Dianne M. Tapiolas,
  • Catherine H. Liptrot and
  • Cherie A. Motti

31 July 2012

The methanol extract of a Sinularia sp., collected from Bowden Reef, Queensland, Australia, yielded ten natural products. These included the new nitrogenous diterpene (4R*,5R*,9S*,10R*,11Z)-4-methoxy-9-((dimethylamino)-methyl)-12,15-epoxy-11(13)-en-d...

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Mar. Drugs - ISSN 1660-3397