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Medicina, Volume 58, Issue 1

2022 January - 141 articles

Cover Story: The symptoms and orthostatic stress findings of patients with long-haul COVID-19 resemble those of patients with ME/CFS. We compared the symptoms of patients with COVID-19 with those of patients with ME/CFS and with those of healthy controls. The core ME/CFS symptom clusters and tilt-induced cerebral blood flow reductions were identical between patients with long-haul COVID-19 and those with ME/CFS and were significantly greater compared with healthy controls. The findings of the symptoms and cerebral blood flow abnormalities in patients with long-haul COVID-19 and those with ME/CFS being similar support the notion that an infection in patients with long-haul COVID-19 acts as a trigger for ME/CFS. View this paper
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Articles (141)

  • Case Report
  • Open Access
5,708 Views
5 Pages

17 January 2022

Cerebral venous sinus thrombosis (CVST) is a rare venous thromboembolic disease that affects young adults in their thirties, with a female predilection. Head trauma accounts for only 1–3% of cases among possible etiologies. Here, we present a p...

(This article belongs to the Section Ophthalmology)
  • Review
  • Open Access
43 Citations
26,102 Views
14 Pages

Analgesic Effects of Interferential Current Therapy: A Narrative Review

  • Érika Patrícia Rampazo and
  • Richard Eloin Liebano

17 January 2022

Background and Objectives: Transcutaneous electrical stimulation of low- and medium-frequency currents is commonly used in pain management. Interferential current (IFC) therapy, a medium frequency alternating current therapy that reportedly reduces s...

(This article belongs to the Special Issue Transcutaneous Electrical Nerve Stimulation (TENS) and Neuromodulation Techniques for Pain Management)
  • Article
  • Open Access
2 Citations
3,071 Views
8 Pages

17 January 2022

Background and Objectives: Basal cell carcinomas (BCCs) are the most frequent skin tumors; although they usually exhibit a good prognosis, it has been reported that there is a 2–8% rate of local recurrence of surgically-excised BCCs, even in th...

(This article belongs to the Section Dermatology)
  • Article
  • Open Access
2,974 Views
11 Pages

Inter-Specialty Controversies on the Treatment of Cardiovascular Diseases during Pregnancy: A Questionnaire Study

  • Dominika Dziadosz,
  • Katarzyna Dudzic,
  • Irmina Morawska,
  • Dominika Topolska,
  • Katarzyna Urban,
  • Katarzyna Mizia-Stec and
  • Łukasz J. Krzych

17 January 2022

Background and Objectives: Management of cardiovascular disease (CVD) during pregnancy is challenging and usually requires eminence-based decisions due to limited strong-evidence data in this field. The purpose of our study was to compare the attitud...

(This article belongs to the Section Cardiology)
  • Review
  • Open Access
21 Citations
9,038 Views
12 Pages

The Thyroid Gland: A Revision Study on Its Vascularization and Surgical Implications

  • Jacopo J. V. Branca,
  • Alfredo Lascialfari Bruschi,
  • Antonino Marcello Pilia,
  • Donatello Carrino,
  • Giulia Guarnieri,
  • Massimo Gulisano,
  • Alessandra Pacini and
  • Ferdinando Paternostro

17 January 2022

Background: The “classic” thyroid gland arterial vascularization takes into account two superior thyroid arteries (STA), two inferior thyroid arteries (ITA) and, occasionally, a thyroid ima artery (TIMA). The present review focuses on exp...

(This article belongs to the Section Surgery)
  • Reply
  • Open Access
2,289 Views
3 Pages

Reply to Sagliocco, O.; Betelli, M. Comment on “Fierro et al. Severe Hypotension, Bradycardia and Asystole after Sugammadex Administration in an Elderly Patient. Medicina 2021, 57, 79”

  • Carmen Fierro,
  • Alessandro Medoro,
  • Donatella Mignogna,
  • Carola Porcile,
  • Silvia Ciampi,
  • Emanuele Foderà,
  • Romeo Flocco,
  • Claudio Russo and
  • Gennaro Martucci

17 January 2022

We thank Dr. Sagliocco and Dr. Betelli for their comments [...]

  • Review
  • Open Access
8 Citations
4,894 Views
15 Pages

Biliary Tree Diagnostics: Advances in Endoscopic Imaging and Tissue Sampling

  • Matteo Ghisa,
  • Angelo Bellumat,
  • Manuela De Bona,
  • Flavio Valiante,
  • Marco Tollardo,
  • Gaia Riguccio,
  • Angelo Iacobellis,
  • Edoardo Savarino and
  • Andrea Buda

17 January 2022

The diagnostic approach to the biliary tree disorders can be challenging, especially for biliary strictures. Albeit the great diagnostic impact of endoscopic retrograde cholangiopancreatography (ERCP) which allows one to obtain fluoroscopic imaging a...

(This article belongs to the Special Issue Recent Advances in Biliopancreatic Endoscopy)
  • Case Report
  • Open Access
6 Citations
4,919 Views
5 Pages

Duodenal Ulcer with Massive Gastrointestinal Hemorrhage as an Initial Manifestation in Multiple Myeloma with Extramedullary Disease: A Case Report

  • Hao-Tse Chiu,
  • Po-Huang Chen,
  • Hao Yen,
  • Chao-Yang Chen,
  • Chih-Wei Yang,
  • Yu-Hong Liu,
  • Wu-Feng Hsieh,
  • Shih-Hao Chou and
  • Ta-Wei Pu

16 January 2022

Plasma cell neoplasms are characterized by dysregulated proliferation of mature B cells, which can present with either single (solitary plasmacytoma) or systemic (multiple myeloma (MM)) involvement. MM with extramedullary plasmacytoma (EMP) is a rare...

  • Article
  • Open Access
13 Citations
3,758 Views
8 Pages

Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants

  • Domenico M. Romeo,
  • Martina Ricci,
  • Federica Mirra,
  • Ilaria Venezia,
  • Maria Mallardi,
  • Elisa Pede and
  • Eugenio Mercuri

16 January 2022

Background and Objectives: Preterm infants are at higher risk of neurodevelopmental impairment both at preschool and school ages, even in the absence of major neurological deficits. The early identification of children at risk is essential for early...

(This article belongs to the Special Issue Clinical Advances in Pediatric Neurology)
  • Case Report
  • Open Access
6 Citations
3,063 Views
5 Pages

15 January 2022

Endoscopic biliary stent insertion is a well-established procedure that is indispensable in the management of various benign and malignant biliary disorders, and one that helps prevent mortality related to invasive surgical procedures. We report a ra...

(This article belongs to the Special Issue Emergency Medicine and Emergency Room Medical Issues)
  • Case Report
  • Open Access
5 Citations
7,074 Views
8 Pages

Necrotizing Fasciitis of the Thigh as Unusual Colonoscopic Polypectomy Complication: Review of the Literature with Case Presentation

  • Sara Sablone,
  • Elpiniki Lagouvardou,
  • Gerardo Cazzato,
  • Francesco Carravetta,
  • Roberto Maselli,
  • Francesco Merlanti,
  • Davide Fiore Bavaro,
  • Antonio De Donno,
  • Francesco Introna and
  • Onofrio Caputi Iambrenghi

15 January 2022

Necrotizing fasciitis (NF) is an infection characterized by necrosis of the superficial muscle fascia and surrounding soft tissues. It usually occurs following skin breaches from penetrating traumas or high-degree burns. Less frequently, it could be...

(This article belongs to the Special Issue Update in Forensic Sciences)
  • Systematic Review
  • Open Access
42 Citations
8,228 Views
11 Pages

Awareness, Knowledge, Attitude, and Practice of Teledentistry among Dental Practitioners during COVID-19: A Systematic Review and Meta-Analysis

  • Galvin Sim Siang Lin,
  • Sze Hui Koh,
  • Karyn Zuhuan Ter,
  • Chia Wei Lim,
  • Sharmin Sultana and
  • Wen Wu Tan

15 January 2022

Background and Objectives: This systemic review aims to appraise and analyse the awareness, knowledge, attitude, and practice of teledentistry among dental practitioners during COVID-19. Materials and Methods: This review was registered in the PROSPE...

(This article belongs to the Special Issue Dental Care and Oral Health during the COVID-19 Pandemic)
  • Review
  • Open Access
30 Citations
14,924 Views
15 Pages

Selective IgA Deficiency and Allergy: A Fresh Look to an Old Story

  • Bianca Laura Cinicola,
  • Federica Pulvirenti,
  • Martina Capponi,
  • Marta Bonetti,
  • Giulia Brindisi,
  • Alessandra Gori,
  • Giovanna De Castro,
  • Caterina Anania,
  • Marzia Duse and
  • Anna Maria Zicari

15 January 2022

Selective IgA deficiency (SIgAD) is the most common human primary immune deficiency (PID). It is classified as a humoral PID characterized by isolated deficiency of IgA (less than 7 mg/dL but normal serum IgG and IgM) in subjects greater than 4 years...

(This article belongs to the Special Issue Pediatric Allergy and Respiratory Diseases)
  • Article
  • Open Access
6 Citations
3,773 Views
7 Pages

Seroprevalence and Risk Factors of Trichinella spiralis Infection in Blood Donors from Western Romania

  • Radu Pavel,
  • Sorin Ursoniu,
  • Ana Alexandra Paduraru,
  • Rodica Lighezan,
  • Maria Alina Lupu and
  • Tudor Rares Olariu

15 January 2022

Background and Objectives: Trichinellosis, a serious and sometimes fatal human disease, is a foodborne zoonotic disease with worldwide distribution caused by parasitic nematodes of the genus Trichinella. Humans are infected with Trichinella larvae th...

(This article belongs to the Special Issue Infections and Infectious Diseases: Epidemiology, Mechanisms of Infection and Treatment Options)
  • Case Report
  • Open Access
4,318 Views
7 Pages

Medulloblastoma Presenting as Severe Headache during Pregnancy: A Case Report and Review of the Literature

  • Francesca Gabriela Paslaru,
  • Anca Maria Panaitescu,
  • Elena Nestian,
  • George Iancu,
  • Alina Veduta,
  • Alexandru Catalin Paslaru,
  • Lucian Gheorghe Pop and
  • Radu Mircea Gorgan

14 January 2022

Headache is a common complaint during pregnancy and the puerperium. The differentiation between a benign headache and a headache that has an underlying more endangering cause, such as an intracranial tumor, can be difficult and often requires diagnos...

(This article belongs to the Special Issue High-Risk Pregnancy)
  • Article
  • Open Access
6 Citations
4,214 Views
11 Pages

14 January 2022

Background and Objective: This study assessed comorbidities and health-related quality of life (HRQOL) in subjects with lumbar spine osteoarthritis (OA) in the Korean population. Materials and Methods: We analyzed 3256 subjects who were 50 years or o...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
3 Citations
4,607 Views
8 Pages

Information Survey on the Use of Complementary and Alternative Medicine

  • Marco Paoloni,
  • Francesco Agostini,
  • Sergio Bernasconi,
  • Gianni Bona,
  • Carlo Cisari,
  • Massimo Fioranelli,
  • Marco Invernizzi,
  • Antonello Madeo,
  • Marco Matucci-Cerinic and
  • Andrea Bernetti
  • + 4 authors

14 January 2022

Background and Objectives: Complementary and alternative medicines (CAMs) are generally considered non-scientific and poor effective therapies. Nevertheless, CAMs are extensively used in common clinical practice in Western countries. We decided to pr...

  • Article
  • Open Access
13 Citations
5,524 Views
13 Pages

Usefulness of Serial Multiorgan Point-of-Care Ultrasound in Acute Heart Failure: Results from a Prospective Observational Cohort

  • Marta Torres-Arrese,
  • Gonzalo García de Casasola-Sánchez,
  • Manuel Méndez-Bailón,
  • Esther Montero-Hernández,
  • Marta Cobo-Marcos,
  • Mercedes Rivas-Lasarte,
  • Luis Caurcel-Díaz,
  • Pablo Rodríguez-Fuertes,
  • Tomas Villén-Villegas and
  • Yale Tung-Chen

14 January 2022

Background and Objectives: Acute heart failure (AHF) is a common disease and a cause of high morbidity and mortality, constituting a major health problem. The main purpose of this study was to determine the impact of multiorgan ultrasound in identify...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
15 Citations
5,516 Views
11 Pages

Risk Factors for Urological Complications Associated with Caesarean Section—A Case-Control Study

  • Viorel Dragos Radu,
  • Anda Ioana Pristavu,
  • Angela Vinturache,
  • Pavel Onofrei,
  • Demetra Gabriela Socolov,
  • Alexandru Carauleanu,
  • Lucian Boiculese,
  • Sadyie Ioana Scripcariu and
  • Radu Cristian Costache

14 January 2022

Background and Objectives: Acute urologic complications, including bladder and/or ureteric injury, are rare but known events occurring at the time of caesarean section (CS). Delayed or inadequate management is associated with increased morbidity and...

(This article belongs to the Special Issue High-Risk Pregnancy)
  • Feature Paper
  • Review
  • Open Access
19 Citations
5,900 Views
16 Pages

Deciphering Respiratory-Virus-Associated Interferon Signaling in COPD Airway Epithelium

  • Hong Guo-Parke,
  • Dermot Linden,
  • Sinéad Weldon,
  • Joseph C. Kidney and
  • Clifford C. Taggart

13 January 2022

COPD is a chronic lung disorder characterized by a progressive and irreversible airflow obstruction, and persistent pulmonary inflammation. It has become a global epidemic affecting 10% of the population, and is the third leading cause of death world...

(This article belongs to the Special Issue Respiratory Immune Responses during Infection and Pollution Inhalation)
  • Review
  • Open Access
54 Citations
14,276 Views
17 Pages

Difficult Biliary Stones: A Comprehensive Review of New and Old Lithotripsy Techniques

  • Edoardo Troncone,
  • Michelangela Mossa,
  • Pasquale De Vico,
  • Giovanni Monteleone and
  • Giovanna Del Vecchio Blanco

13 January 2022

Biliary stones represent the most common indication for therapeutic endoscopic retrograde cholangiopancreatography. Many cases are successfully managed with biliary sphincterotomy and stone extraction with balloon or basket catheters. However, more c...

(This article belongs to the Special Issue Recent Advances in Biliopancreatic Endoscopy)
  • Article
  • Open Access
5 Citations
5,412 Views
10 Pages

13 January 2022

Background and Objectives: Home fertility assessment methods (FAMs) for natural family planning (NFP) have technically evolved with the objective metrics of urinary luteinizing hormone (LH), estrone-3-glucuronide (E3G) and pregnanediol-3-glucuronide...

  • Article
  • Open Access
3 Citations
3,748 Views
11 Pages

Risk Factors for Therapeutic Intervention of Remdesivir in Mild to Moderate COVID-19—A Single-Center Retrospective Study of the COVID-19 Fourth Pandemic Period in Wakayama, Japan

  • Shinobu Tamura,
  • Takahiro Kaki,
  • Mayako Niwa,
  • Yukiko Yamano,
  • Shintaro Kawai,
  • Yusuke Yamashita,
  • Harumi Tanaka,
  • Yoshinobu Saito,
  • Yoshinori Kajimoto and
  • Masaya Hironishi
  • + 4 authors

13 January 2022

Background and Objectives: The incidence of coronavirus disease 2019 (COVID-19) has increased in Wakayama, Japan, due to the spread of the highly infectious B.1.1.7 variant. Before this event, the medical systems were almost unaffected. We aimed to a...

(This article belongs to the Special Issue Hospital Epidemiology and Infection Control in the Era of the COVID-19 Pandemic)
  • Article
  • Open Access
6 Citations
3,777 Views
9 Pages

13 January 2022

Background and Objectives: Current guidelines have limited the performance of complete lymph node dissection (CLND) for patients with clinically detectable lymphatic metastases. Despite the limitations of this surgical procedure, secondary lymphedema...

(This article belongs to the Special Issue Vasorum Lymphaticorum: From the Discovery of the Lymphatic System to the New Perspectives in Microsurgical Reconstruction and Patient Rehabilitation)
  • Review
  • Open Access
2 Citations
4,472 Views
6 Pages

13 January 2022

The novel coronavirus disease 2019 (COVID-19) is an infectious disease with multi-organ involvement, including the cardiovascular system. The disease may cause several cardiovascular complications, and may increase morbidity and mortality among patie...

(This article belongs to the Special Issue Heart Failure in the Era of COVID 19)
  • Article
  • Open Access
9 Citations
4,329 Views
11 Pages

Fluoroscopy-Assisted C1–C2 Posterior Fixation for Atlantoaxial Instability: A Single-Center Case Series of 78 Patients

  • Charles Tatter,
  • Alexander Fletcher-Sandersjöö,
  • Oscar Persson,
  • Gustav Burström,
  • Erik Edström and
  • Adrian Elmi-Terander

12 January 2022

Background and Objectives: Posterior C1–C2 fixation, with trans-articular screws (TAS) or screw-rod-construct (SRC), is the main surgical technique for atlantoaxial instability, and can be performed with a fluoroscopy-assisted free-handed techn...

(This article belongs to the Section Surgery)
  • Article
  • Open Access
13 Citations
7,790 Views
12 Pages

Sequential Use of CO2 Laser Prior to Nd:YAG and Dye Laser in the Management of Non-Facial Warts: A Retrospective Study

  • Luigi Bennardo,
  • Gaia Fasano,
  • Federica Tamburi,
  • Elena Zappia,
  • Francesco Rizzuto,
  • Steven Paul Nisticò and
  • Giovanni Cannarozzo

12 January 2022

Background and Objectives: Warts are benign lesions of viral etiology characterized by a hyperkeratotic appearance tending to spread across the skin surface. Various treatments have been proposed to manage this condition, such as acids, imiquimod, ph...

(This article belongs to the Special Issue Lasers, Lights and New Technologies in Medicine and Surgery)
  • Article
  • Open Access
8 Citations
5,428 Views
11 Pages

Implantoplasty Improves Clinical Parameters over a 2-Year Follow-Up: A Case Series

  • Orlando Martins,
  • Philipp Sahrmann,
  • João Ramos,
  • Francisco Caramelo,
  • Sérgio Matos and
  • Isabel Poiares Baptista

12 January 2022

Background and Objectives: Peri-implantitis treatment is still undefined. Regenerative treatment is expensive and technically demanding due to the need to handle biomaterials, membranes and different methodologies of decontamination. Resective treatm...

(This article belongs to the Special Issue Outcome of Minimally Invasive Techniques in Dentistry)
  • Article
  • Open Access
2 Citations
4,128 Views
8 Pages

Prognosis of Subcutaneous Mastectomy for Special Types of Breast Cancer

  • Tsuyoshi Nakagawa,
  • Goshi Oda,
  • Hiroki Mori,
  • Noriko Uemura,
  • Iichiro Onishi,
  • Noriko Sagawa,
  • Tomoyuki Fujioka,
  • Mio Mori,
  • Kazunori Kubota and
  • Hiroyuki Uetake
  • + 2 authors

12 January 2022

Background and objectives: In the treatment of the special type of breast cancer (STBC), the choice of chemotherapeutic agents is often based on the characteristic features of the histological type. On the other hand, the surgical strategy is usually...

(This article belongs to the Section Surgery)
  • Article
  • Open Access
11 Citations
5,359 Views
8 Pages

Incidence of Emergency Peripartum Hysterectomy in a Tertiary Obstetrics Unit in Romania

  • Nicolae Gică,
  • Carina Ragea,
  • Radu Botezatu,
  • Gheorghe Peltecu,
  • Corina Gică and
  • Anca Maria Panaitescu

12 January 2022

Background and Objectives: Emergency peripartum hysterectomy (EPH) is a life-saving surgical procedure performed when medical and surgical conservative measures fail to control postpartum hemorrhage. The objective of this study was to estimate the in...

(This article belongs to the Special Issue High-Risk Pregnancy)
  • Case Report
  • Open Access
4 Citations
3,316 Views
10 Pages

11 January 2022

Antiretroviral therapy (ART) can restore protective immune responses against opportunistic infections (OIs) and reduce mortality in patients with human immunodeficiency virus (HIV) infections. Some patients treated with ART may develop immune reconst...

(This article belongs to the Special Issue Infections and Infectious Diseases: Epidemiology, Mechanisms of Infection and Treatment Options)
  • Review
  • Open Access
6 Citations
4,695 Views
9 Pages

Experimental and Emerging Free Fatty Acid Receptor Agonists for the Treatment of Type 2 Diabetes

  • Angelo Maria Patti,
  • Rosaria Vincenza Giglio,
  • Nikolaos Papanas,
  • Dragos Serban,
  • Anca Pantea Stoian,
  • Kalliopi Pafili,
  • Khalid Al Rasadi,
  • Kanya Rajagopalan,
  • Ali A. Rizvi and
  • Manfredi Rizzo
  • + 1 author

11 January 2022

The current management of Type 2 Diabetes Mellitus (T2DM) includes incretin-based treatments able to enhance insulin secretion and peripheral insulin sensitivity as well as improve body mass, inflammation, plasma lipids, blood pressure, and cardiovas...

(This article belongs to the Special Issue Endocrinology in the Time of COVID-19)
  • Article
  • Open Access
2,849 Views
9 Pages

Dimethylarginines in Children after Anti-Neoplastic Treatment

  • Michalina Jezierska,
  • Anna Owczarzak and
  • Joanna Stefanowicz

11 January 2022

Background and Objectives: According to a recent Cochrane systematic review, renal impairment can develop in 0–84% of childhood cancer survivors in the future. The renal function impairment in this patient group can be related to nephrectomy, n...

(This article belongs to the Section Oncology)
  • Review
  • Open Access
18 Citations
4,689 Views
7 Pages

Primary Non-Hodgkin Uterine Lymphoma of the Cervix: A Literature Review

  • Cristina Capsa,
  • Laura Aifer Calustian,
  • Sabina Antonela Antoniu,
  • Eugen Bratucu,
  • Laurentiu Simion and
  • Virgiliu-Mihail Prunoiu

10 January 2022

Introduction: Non-Hodgkin lymphomas (NHL) comprise 85% of the total lymphomas diagnosed, with the histological type of diffuse large B-cell lymphomas (DLBCL) being the most prevalent in adults. In about 40% of cases, the location is extranodal. Uteri...

(This article belongs to the Section Oncology)
  • Case Report
  • Open Access
7 Citations
4,232 Views
7 Pages

Genital Prolapse in Pregnant Woman as a Presentation of Aggressive Angiomyxoma: Case Report and Literature Review

  • María Pilar Espejo-Reina,
  • Miriam Prieto-Moreno,
  • Marina De-Miguel-Blanc,
  • Daniela María Pérez-Martínez,
  • Jesús Salvador Jiménez-López and
  • Susana Monís-Rodríguez

10 January 2022

Background: Aggressive angiomyxoma is a rare entity within mesenchymal cell neoplasms, especially in pregnant women. Its main characteristic is the ability to infiltrate neighboring structures and to recur. Case Presentation: We present the case of a...

(This article belongs to the Section Obstetrics and Gynecology)
  • Case Report
  • Open Access
1 Citations
2,425 Views
6 Pages

Case of Patient with AML with Complex Karyotype including Ultra-Rare t(4;8)(q32;q13), t(4;11)(q21;p15) and Familial Aggregation of Myeloid Malignancies

  • Sławomir Milczarek,
  • Ewa Studniak,
  • Bartłomiej Baumert,
  • Michał Janowski,
  • Wioleta Bonda,
  • Joanna Pietrzak,
  • Aleksandra Łanocha,
  • Edyta Paczkowska,
  • Barbara Zdziarska and
  • Bogusław Machaliński

10 January 2022

We present a unique case of a young woman with acute myeloid leukemia (AML) with complex karyotype. The presence of the t(4;11)(q23;p15) is extremely rare in myeloid leukemias, while t(4;8)(q32;q13) has not yet been described in any leukemia referenc...

(This article belongs to the Section Genetics and Molecular Medicine)
  • Review
  • Open Access
5 Citations
19,106 Views
19 Pages

Dysbarism: An Overview of an Unusual Medical Emergency

  • Gabriele Savioli,
  • Claudia Alfano,
  • Christian Zanza,
  • Gaia Bavestrello Piccini,
  • Angelica Varesi,
  • Ciro Esposito,
  • Giovanni Ricevuti and
  • Iride Francesca Ceresa

10 January 2022

Dysbarism is a general term which includes the signs and symptoms that can manifest when the body is subject to an increase or a decrease in the atmospheric pressure which occurs either at a rate or duration exceeding the capacity of the body to adap...

  • Article
  • Open Access
12 Citations
3,342 Views
17 Pages

Evaluation of the Efficacy of Mineralized Dentin Graft in the Treatment of Intraosseous Defects: An Experimental In Vivo Study

  • Nuray Özkahraman,
  • Nilüfer Bölükbaşı Balcıoğlu,
  • Merva Soluk Tekkesin,
  • Yusuf Altundağ and
  • Serdar Yalçın

10 January 2022

Background and Objectives: Dentin grafts have osteoinductive and osteoconductive properties and are considered as an alternative to autogenous graft. This study evaluates the efficacy of autogenous mineralized dentin graft (AMDG) alone or with xenogr...

(This article belongs to the Section Dentistry and Oral Health)
  • Review
  • Open Access
11 Citations
5,180 Views
9 Pages

Human Stem Cell Transplantation for Retinal Degenerative Diseases: Where Are We Now?

  • Ignacio Alcalde,
  • Cristina Sánchez-Fernández,
  • Carla Martín,
  • Nagore De Pablo,
  • Nahla Jemni-Damer,
  • Gustavo V. Guinea,
  • Jesús Merayo-Lloves and
  • Susana Del Olmo-Aguado

10 January 2022

Background and Objectives: Irreversible visual impairment is mainly caused by retinal degenerative diseases such as age-related macular degeneration and retinitis pigmentosa. Stem cell research has experienced rapid progress in recent years, and rese...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
39 Citations
7,607 Views
8 Pages

Lower Limb Amputation Rates in Germany

  • Nike Walter,
  • Volker Alt and
  • Markus Rupp

10 January 2022

Background and Objectives: The current epidemiology of lower limb amputations is unknown. Therefore, the purpose of this study was to determine (1) lower extremity amputation rates as a function of age, gender, and amputation level between 2015 and 2...

(This article belongs to the Section Epidemiology & Public Health)
  • Review
  • Open Access
21 Citations
4,813 Views
9 Pages

Global Impact of COVID-19 on Colorectal Cancer Screening: Current Insights and Future Directions

  • Jonathan Kopel,
  • Bojana Ristic,
  • Gregory L. Brower and
  • Hemant Goyal

10 January 2022

The coronavirus disease 2019 (COVID-19) pandemic has brought significant challenges to many aspects of healthcare delivery since the first reported case in early December 2019. Once in the body, SARS-CoV-2 can spread to other digestive organs, such a...

(This article belongs to the Special Issue Therapeutic Landscapes in Colorectal Carcinoma)
  • Article
  • Open Access
2,491 Views
12 Pages

Process Evaluation of Lumbar Interbody Fusion Surgeries in Five Dutch Hospitals: A Qualitative Analysis

  • Ruud Droeghaag,
  • Inge J. M. H. Caelers,
  • Aggie T. G. Paulus,
  • Wouter L. W. van Hemert,
  • Henk van Santbrink and
  • on behalf of The LIFT-Study Group

9 January 2022

Background and Objectives: Only limited qualitative research concerning instrumented spine surgeries has been published, despite the increasing number of these surgeries and the evident importance of qualitative analysis of the processes surrounding...

(This article belongs to the Special Issue Lumbar Spinal Stenosis: Diagnosis and Treatment Options)
  • Article
  • Open Access
13 Citations
7,991 Views
11 Pages

9 January 2022

Background and objectives: Orthostatic intolerance (OI) is a clinical condition in which symptoms worsen upon assuming and maintaining upright posture and are ameliorated by recumbency. OI has a high prevalence in patients with myalgic encephalomyeli...

(This article belongs to the Special Issue Chronic Fatigue Syndrome: From Clinical Observations to Unifying Hypotheses of Disease Mechanisms)
  • Article
  • Open Access
5 Citations
3,309 Views
8 Pages

Proposal of an Algorithm to Early Detect Attenuated Type I Mucopolysaccharidosis (MPS Ia) among Children with Growth Abnormalities

  • Federico Baronio,
  • Stefano Zucchini,
  • Francesco Zulian,
  • Mariacarolina Salerno,
  • Rossella Parini,
  • Alessandro Cattoni,
  • Federica Deodato,
  • Alberto Gaeta,
  • Carla Bizzarri and
  • Andrea Pession
  • + 1 author

8 January 2022

Background and Objectives: Diagnostic delay is common in attenuated Mucopolysaccharidosis Type I (MPS Ia) due to the rarity of the disease and the variability of clinical presentation. Short stature and impaired growth velocity are frequent findings...

(This article belongs to the Section Pediatrics)
  • Article
  • Open Access
8 Citations
3,299 Views
15 Pages

Periostin in Angiogenesis and Inflammation in CRC—A Preliminary Observational Study

  • Agnieszka Kula,
  • Miriam Dawidowicz,
  • Sylwia Mielcarska,
  • Paweł Kiczmer,
  • Magdalena Chrabańska,
  • Magdalena Rynkiewicz,
  • Elżbieta Świętochowska and
  • Dariusz Waniczek

8 January 2022

Background and Objectives: To assess the periostin level and the concentrations of pro-inflammatory cytokines: TNFα, IFN-γ, IL-1β and IL-17 in tumor and marginal tissues of CRC and to investigate the influence of periostin on angioge...

  • Article
  • Open Access
7 Citations
4,606 Views
14 Pages

Analysis of the Increase of Vascular Cell Adhesion Molecule-1 (VCAM-1) Expression and the Effect of Exposure in a Hyperbaric Chamber on VCAM-1 in Human Blood Serum: A Cross-Sectional Study

  • Katarzyna Van Damme-Ostapowicz,
  • Mateusz Cybulski,
  • Mariusz Kozakiewicz,
  • Elżbieta Krajewska-Kułak,
  • Piotr Siermontowski,
  • Marek Sobolewski and
  • Dorota Kaczerska

8 January 2022

Background and Objectives: Vascular cell adhesion molecule-1 (VCAM-1) was identified as a cell adhesion molecule that helps to regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages an...

(This article belongs to the Special Issue Hyperbaric Medicine)
  • Article
  • Open Access
2 Citations
5,248 Views
9 Pages

Rheumatological Adverse Events Following Immunotherapy for Cancer

  • Ioana Cretu,
  • Bogdan Cretu,
  • Catalin Cirstoiu,
  • Adrian Cursaru,
  • Mihaela Milicescu,
  • Mihai Bojinca and
  • Ruxandra Ionescu

8 January 2022

Background and Objectives: The occurrence of rheumatological side effects in a patient after receiving immunotherapy for cancer is becoming increasingly common. Oncologists often fail to diagnose and refer affected patients to rheumatologists. This p...

  • Article
  • Open Access
7 Citations
3,757 Views
14 Pages

Hybrid Surgery for Severe Mitral Valve Calcification: Limitations and Caveats for an Open Transcatheter Approach

  • Erik Bagaev,
  • Ahmad Ali,
  • Shekhar Saha,
  • Sebastian Sadoni,
  • Martin Orban,
  • Michael Naebauer,
  • Julinda Mehilli,
  • Steffen Massberg,
  • Andreas Oberbach and
  • Christian Hagl

7 January 2022

Background and Objectives: Mitral stenosis with extensive mitral annular calcification (MAC) remains surgically challenging in respect to clinical outcome. Prolonged surgery time with imminent ventricular rupture and systolic anterior motion can be c...

(This article belongs to the Special Issue Innovations in Minimally Invasive Cardiac Surgery)
  • Systematic Review
  • Open Access
15 Citations
5,115 Views
11 Pages

Importance of Osseoperception and Tactile Sensibility during Masticatory Function in Different Prosthetic Rehabilitations: A Review

  • Diego González-Gil,
  • Ibrahim Dib-Zaitum,
  • Javier Flores-Fraile and
  • Joaquín López-Marcos

7 January 2022

Background and Objectives: Tactile sensibility is an important characteristic for evaluating the masticatory efficiency in different occlusal situations. When a tooth is extracted, relevant proprioceptors from the periodontal ligament get lost; and a...

(This article belongs to the Section Dentistry and Oral Health)

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Medicina - ISSN 1648-9144