You are currently viewing a new version of our website. To view the old version click .

Current Issues in Molecular Biology, Volume 47, Issue 6

June 2025 - 93 articles

Cover Story: In this review, we examine the complex mechanisms underlying neuroinflammatory responses, with a focus on the interactions between glial cells and neurons. The dualistic role of neuroinflammation is further investigated, highlighting its ability to promote neuroprotection in acute phases while also contributing to neuronal injury and degeneration during chronic activation. In this review, we also consider innovative therapeutic approaches designed to target neuroinflammatory processes. A thorough understanding of the regulatory balance within neuroinflammatory networks is essential for the development of effective treatments for several neurological pathologies. Lastly, we provide an integrative summary of current evidence and highlight emerging directions in neuroinflammation research. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (93)

  • Article
  • Open Access
959 Views
15 Pages

Millipedes (Diplopoda) are crucial decomposers in soil ecosystems, as they play a vital role in organic matter degradation while also holding potential as bioindicators of environmental health. This study deciphered the complete mitogenomes of four m...

  • Article
  • Open Access
1,273 Views
14 Pages

L-Ascorbic Acid (LAA) Supplementation as a Potential Treatment for Skin Aging: Regulation of Adipose Tissue Mesenchymal Stem Cells (AT-MSCs) Protein Secretion

  • Komang Ardi Wahyuningsih,
  • I. Gede Eka Wiratnaya,
  • I. Wayan Weta,
  • I. Gde Raka Widiana,
  • Wimpie I. Pangkahila,
  • Ida Ayu Ika Wahyuniari,
  • I. Made Muliarta,
  • Veronika Maria Sidharta and
  • Assyafiya Salwa

Skin aging is mostly caused by the accumulation of reactive oxygen species (ROS) that lead to cellular dysfunction. One promising therapy for skin aging is the secretome product of adipose tissue mesenchymal stem cells (AT-MSCs). L-ascorbic acid (LAA...

  • Review
  • Open Access
1,689 Views
47 Pages

Integrating Genomics and Molecular Biology in Understanding Peritoneal Adhesion

  • Mirela Lungu,
  • Claudiu N. Lungu,
  • Andreea Creteanu and
  • Mihaela C. Mehedinti

Peritoneal adhesions following surgical injury remain a major clinical challenge, often resulting in severe complications, such as intestinal obstruction, chronic pain, and infertility. This review systematically integrates recent genomic and molecul...

  • Article
  • Open Access
1 Citations
834 Views
12 Pages

Association of DROSHA Variants with Susceptibility and Outcomes in Childhood Acute Lymphoblastic Leukemia

  • Ioannis Kyriakidis,
  • Iordanis Pelagiadis,
  • Charalampos Pontikoglou,
  • Helen A. Papadaki and
  • Eftichia Stiakaki

MicroRNAs are key regulators of lymphoid differentiation, exhibiting a pivotal role in acute lymphoblastic leukemia (ALL) biology and prognosis. The initial steps of canonical miRNA biogenesis involve the microprocessor complex processing the primary...

  • Review
  • Open Access
3 Citations
2,095 Views
22 Pages

The final recipient of nanoparticles, including various types of copper-based nanoparticles (Cu-based NPs), is the aquatic environment. Their increased production, especially as a component of antimicrobial agents, raises concerns about uncontrolled...

  • Review
  • Open Access
1,429 Views
19 Pages

C17-polyacetylenic (PA) oxylipins are bioactive compounds in carrots (Daucus carota L.) with structurally unique features and diverse biological roles. These PA-derived compounds have garnered attention for their potential contributions to human heal...

  • Review
  • Open Access
12 Citations
4,797 Views
26 Pages

Integrating Artificial Intelligence in Next-Generation Sequencing: Advances, Challenges, and Future Directions

  • Konstantina Athanasopoulou,
  • Vasiliki-Ioanna Michalopoulou,
  • Andreas Scorilas and
  • Panagiotis G. Adamopoulos

The integration of artificial intelligence (AI) into next-generation sequencing (NGS) has revolutionized genomics, offering unprecedented advancements in data analysis, accuracy, and scalability. This review explores the synergistic relationship betw...

  • Article
  • Open Access
1,282 Views
16 Pages

Enterococcus faecalis (E. faecalis) is a major pathogen responsible for refractory apical periodontitis (RAP). It can penetrate deep into dentinal tubules, form persistent biofilms, and exhibit antibiotic resistance, thereby limiting the efficacy of...

  • Article
  • Open Access
1,573 Views
12 Pages

Restoration of Hair Luster via Novel Biomarker COL7A1 by Minoxidil, Caffeine, and Biotin

  • Ngoc Ha Nguyen,
  • Young In Lee,
  • Hyeon-Ah Do,
  • Inhee Jung,
  • Jae Hyun Park,
  • Sung Jun Lee and
  • Ju Hee Lee

Hair luster, a key component of visual hair quality, depends largely on the integrity of the cuticle. While cosmetic products offer temporarily enhanced luster, their effects are limited due to a poor understanding of the underlying molecular mechani...

  • Article
  • Open Access
1 Citations
1,245 Views
17 Pages

Design of New Primer Sets for the Development of a Loop-Mediated Isothermal Amplification for Rapid Detection of Neisseria meningitidis

  • Cuong Viet Vo,
  • Trang Thu Nguyen,
  • Huong Thu Ngo,
  • Lan Anh Thi Bui,
  • Toan Van Trinh,
  • Loan Thi Vu,
  • Hieu Dang Hoang and
  • Phong Quoc Truong

Neisseria meningitidis is a pathogenic bacterial agent that causes meningococcal meningitis in humans. Developing a rapid and low-cost N. meningitidis detection method is crucial, especially for developing countries. This study focuses on the develop...

of 10

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Curr. Issues Mol. Biol. - ISSN 1467-3045